期刊
CHIRALITY
卷 34, 期 8, 页码 1065-1077出版社
WILEY
DOI: 10.1002/chir.23471
关键词
chiral separation; chiral zwitterion ion exchanger; dipeptide; liquid chromatography; reversed-phase mode; separation model
资金
- Russian Foundation for Basic Research [20-53-26007]
- Czech Science Foundation [21-31139J]
In this study, the enantioselectivity of chiral zwitterionic columns (ZWIX (+A) and ZWIX (-A)) on dipeptides under buffer-free reversed-phase conditions was investigated. An electrostatically driven adsorption model was used to analyze the retention characteristics of zwitterionic dipeptides, which showed good fits with both monotonous and U-shaped curves.
Chiral zwitterion ion exchangers represent efficient chiral stationary phases for stereoselective resolution of various analytes including chiral acids, bases, and zwitterions. In this contribution, we have focused on utilization of chiral zwitterionic sorbents, denoted as ZWIX (+A) and ZWIX (-A). These are analogical chiral systems to commercially available columns, Chiralpak ZWIX (+) and Chiralpak ZWIX (-), which are usually operated with buffered mobile phases. In this contribution, we have studied the enantiorecognition power of the ZWIX (+A) and ZWIX (-A) columns on a series of dipeptides operated under buffer-free reversed-phase conditions. Retention characteristics of zwitterionic dipeptides are discussed using an electrostatically driven adsorption model, which provides a good fit with both monotonous and U-shaped curves.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据