Chemical Measurement and Analysis: from Phenomenon to Essence

Comprehensive Summary The review summaries our achievements in optical, electrochemical, as well as mass spectrometry analysis and imaging with high sensitivity, specificity, and spatiotemporal resolution. We promoted the plasmonic imaging system, and developed ultra-sensitive plasmonic nanoprobes for the tracking of single molecules in single living cells, as well as plasmonic nanocatalysts for highly efficient energy conversion. In addition, we contributed a lot in electrogenerated chemiluminescence (ECL) analysis and imaging. Pioneering works including localized surface plasmon resonance (LSPR) enhanced ECL, ECL ratiometric detection, BPE based ECL system, multi-color ECL sensing as well as super-resolved ECL imaging have been initiated by our group. Furthermore, we also dedicated in nanopipette based electrochemical analysis in single living cells, as well as ESI-MS analysis on short time scale. The research works of our group promoted the development of chemical measurement and analysis. What is the most favorite and original chemistry developed in your research group? LSPR enhanced ECL and Bipolar electrochemistry analysis, single particle based single cell analysis and super-resolved imaging. What is the most important personality for scientific research? Strong curiosity, perseverance, strong hands-on ability. How do you supervise your students? Encourage students to read more, think more, discuss more, and try more. How do you keep balance between research and family? Allocating time reasonably. Who influences you mostly in your life? My PhD director, Prof. Hong-Yuan Chen. What are your hobbies? I used to like to play badminton, now I'm learning to play table tennis.

Automated summary

This article summarizes the achievements of the research group in optical, electrochemical, and mass spectrometry analysis and imaging. They have made significant contributions in plasmonic imaging, electrogenerated chemiluminescence analysis, and nanopipette-based electrochemical analysis. Their research works have advanced the development of chemical measurement and analysis.