4.7 Review

Carbon-sulfur bond formation via photochemical strategies: An efficient method for the synthesis of sulfur-containing compounds

期刊

CHINESE CHEMICAL LETTERS
卷 33, 期 4, 页码 1798-1816

出版社

ELSEVIER SCIENCE INC
DOI: 10.1016/j.cclet.2021.09.068

关键词

Visible light; C-S bond formation; Radical; Cyclization; Sulfur-containing compouds

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This review focuses on recent advances in C-S bond formation via visible-light photoredox catalysis, highlighting its potential in pharmaceutical synthesis, synthetic methodology development, and the application of sulfur-containing drugs.
The development of green and convenient methods for C-S bond formation has received significant attention because C-S bond widely occurs in many important pharmaceutical and biological compounds. Recently, visible-light photoredox catalysis has been established as an efficient and general tool for the construction of C-C and C-heteroatom bonds. In this review, we have focused on the research on recent advances in C-S bond formation via visible-light photoredox catalysis, and the growing opportunities they present to the construction of complex chemical scaffolds for applications encompassing bioactive molecules synthesis, synthetic methodology development, and sulfur-containing drugs. We hope that this review will provide chemists with a synthetic tool that will open the door to further development of organsulfur chemistry (C) 2021 Published by Elsevier B.V. on behalf of Chinese Chemical Society and Institute of Materia Medica, Chinese Academy of Medical Sciences.

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