Visible light induced oxidative coupling of purines with arenes

The photocatalyzed synthesis of 9-arylpurines has been developed using 9H-purines and non-activated arenes. This method is highly atom economical using an acridinium photocatalyst induced by visible light under air atmosphere at room temperature. It employs no metal or external oxidant for the synthesis of 9-arylpurine derivatives.(c) 2022 Published by Elsevier B.V. on behalf of Chinese Chemical Society and Institute of Materia Medica, Chinese Academy of Medical Sciences.

Automated summary

This study developed a method for the photocatalyzed synthesis of 9-arylpurines using non-activated arenes and 9H-purines. The process is highly atom economical and does not require the use of metal or external oxidant.