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Stem cell-derived β cells go in monkeys

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CELL STEM CELL
卷 29, 期 4, 页码 500-502

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CELL PRESS
DOI: 10.1016/j.stem.2022.03.010

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Du et al. conducted the first transplantation of 0 cells derived from pluripotent stem cells in diabetic monkeys, as a step towards clinical translation. They observed gradual benefits over months, but also noted immune rejection of the grafts at 5-6 months.
Du et al. transplanted 0 cells derived from pluripotent stem cells in diabetic monkeys for the first time, as an intermediate stage toward clinical translation. They observed benefits unfolding over months but also observed immune rejection of the grafts by 5-6 months.

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