4.8 Editorial Material

Evaluating human genetic support for hypothesized metabolic disease genes

期刊

CELL METABOLISM
卷 34, 期 5, 页码 661-666

出版社

CELL PRESS
DOI: 10.1016/j.cmet.2022.03.011

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资金

  1. NIDDK [5UM1DK105554, 1R01DK125490]
  2. NIH NHLBI [R01HL151855]
  3. NIH NIDDK [UM1DK07861]
  4. National Center for Advancing Translational Sciences, CTSI [UL1TR001881]
  5. National Institute of Diabetes and Digestive and Kidney Disease Diabetes Research Center (DRC) [DK063491]
  6. NIH [HL109650, DK125898, R01DK125898]
  7. American Heart Association

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This study investigates the incorporation of human genetic data in exploring new links between genes and metabolic disease. To facilitate the utilization of genetic data, the authors present an approach that enables researchers to evaluate the human genetic support for experimentally determined hypotheses.
We investigate the extent to which human genetic data are incorporated into studies that hypothesize novel links between genes and metabolic disease. To lower the barriers to using genetic data, we present an approach to enable researchers to evaluate human genetic support for experimentally determined hy-potheses.

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