The RTS,S vaccine-a chance to regain the upper hand malaria?

Malaria is estimated by the World Health Organization (WHO) to have killed 627,000 individuals worldwide in 2020, with nearly 80% of deaths in African children younger than five. The recent WHO approval of the RTS,S/AS01 vaccine, which targets Plasmodium falciparum pre-erythrocytic stages, provides hope that its use combined with other interventions can help reverse the current malaria resurgence.

Automated summary

In 2020, malaria caused the death of an estimated 627,000 individuals worldwide, with a majority of deaths occurring in children under the age of five in Africa. The recent approval of the RTS,S/AS01 vaccine by the World Health Organization (WHO) offers hope in combating the current resurgence of malaria through combined interventions.