4.7 Article

An antiplatelet response gene expression signature is associated with bleeding

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Article Pharmacology & Pharmacy

Aspirin effects on platelet gene expression are associated with a paradoxical, increase in platelet function

Rachel A. Myers et al.

Summary: The study demonstrates a dose-independent effect of aspirin on the platelet transcriptome, potentially acting as an inhibitor of protein synthesis, and correlated with platelet function levels.

BRITISH JOURNAL OF CLINICAL PHARMACOLOGY (2022)

Review Medicine, General & Internal

Management of Antithrombotic Therapy after Acute Coronary Syndromes

Fatima Rodriguez et al.

Summary: Antithrombotic therapy is a crucial element in the treatment of acute coronary syndromes, with a focus on antiplatelet therapy. However, balancing the benefits and bleeding risks remains controversial. This review examines clinical research and recommended approaches to management in this area.

NEW ENGLAND JOURNAL OF MEDICINE (2021)

Article Cardiac & Cardiovascular Systems

Platelet reactivity in response to aspirin and ticagrelor in African-Americans and European-Americans

Margaret Infeld et al.

Summary: Platelet gene polymorphisms are associated with variable on-treatment platelet reactivity and differ by race. African-Americans demonstrated lower platelet reactivity at baseline and on treatment compared to European-Americans. European-Americans experienced greater platelet suppression on aspirin and ticagrelor than African-Americans.

JOURNAL OF THROMBOSIS AND THROMBOLYSIS (2021)

Article Medicine, General & Internal

Antithrombotic Therapy after Acute Coronary Syndrome or PCI in Atrial Fibrillation

Renato D. Lopes et al.

NEW ENGLAND JOURNAL OF MEDICINE (2019)

Article Medicine, General & Internal

Ticagrelor with or without Aspirin in High-Risk Patients after PCI

R. Mehran et al.

NEW ENGLAND JOURNAL OF MEDICINE (2019)

Article Medicine, General & Internal

A Genotype-Guided Strategy for Oral P2Y12 Inhibitors in Primary PCI

Daniel M. F. Claassens et al.

NEW ENGLAND JOURNAL OF MEDICINE (2019)

Article Medicine, General & Internal

Effect of Aspirin on Cardiovascular Events and Bleeding in the Healthy Elderly

J. J. McNeil et al.

NEW ENGLAND JOURNAL OF MEDICINE (2018)

Article Medicine, General & Internal

Effects of Aspirin for Primary Prevention in Persons with Diabetes Mellitus

Louise Bowman et al.

NEW ENGLAND JOURNAL OF MEDICINE (2018)

Article Cardiac & Cardiovascular Systems

Platelet-related biomarkers and their response to inhibition with aspirin and p2y12-receptor antagonists in patients with acute coronary syndrome

Angela Lowenstern et al.

JOURNAL OF THROMBOSIS AND THROMBOLYSIS (2017)

Article Medicine, General & Internal

Development and Validation of a Prediction Rule for Benefit and Harm of Dual Antiplatelet Therapy Beyond 1 Year After Percutaneous Coronary Intervention

Robert W. Yeh et al.

JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION (2016)

Article Biotechnology & Applied Microbiology

Integrin-based therapeutics: biological basis, clinical use and new drugs

Klaus Ley et al.

NATURE REVIEWS DRUG DISCOVERY (2016)

Article Cardiac & Cardiovascular Systems

A Guide for a Cardiovascular Genomics Biorepository: the CATHGEN Experience

William E. Kraus et al.

JOURNAL OF CARDIOVASCULAR TRANSLATIONAL RESEARCH (2015)

Article Cardiac & Cardiovascular Systems

Aspirin Exposure Reveals Novel Genes Associated With Platelet Function and Cardiovascular Events

Deepak Voora et al.

JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY (2013)

Article Cardiac & Cardiovascular Systems

Association Between Periprocedural Bleeding and Long-Term Outcomes Following Percutaneous Coronary Intervention in Older Patients

Sunil V. Rao et al.

JACC-CARDIOVASCULAR INTERVENTIONS (2012)

Article Cardiac & Cardiovascular Systems

Time-dependent changes in non-COX-1-dependent platelet function with daily aspirin therapy

Deepak Voora et al.

JOURNAL OF THROMBOSIS AND THROMBOLYSIS (2012)

Article Public, Environmental & Occupational Health

An automated database case definition for serious bleeding related to oral anticoagulant use

Andrew Cunningham et al.

PHARMACOEPIDEMIOLOGY AND DRUG SAFETY (2011)

Article Hematology

Impact of race and gender on antithrombotic therapy

Davide Capodanno et al.

THROMBOSIS AND HAEMOSTASIS (2010)