相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。Antigen-independent activation enhances the efficacy of 4-1BB-costimulated CD22 CAR T cells
Nathan Singh et al.
NATURE MEDICINE (2021)
Optimization of T Cell Redirecting Strategies: Obtaining Inspirations From Natural Process of T Cell Activation
Yiyuan Gao et al.
FRONTIERS IN IMMUNOLOGY (2021)
Tumor organoid-T-cell coculture systems
Chiara M. Cattaneo et al.
NATURE PROTOCOLS (2020)
Signaling from T cell receptors (TCRs) and chimeric antigen receptors (CARs) on T cells
Ling Wu et al.
CELLULAR & MOLECULAR IMMUNOLOGY (2020)
Clustering of the ζ-Chain Can Initiate T Cell Receptor Signaling
Yuanqing Ma et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2020)
Tuning the Antigen Density Requirement for CAR T-cell Activity
Robbie G. Majzner et al.
CANCER DISCOVERY (2020)
Engineering CAR-T Cells for Next-Generation Cancer Therapy
Mihe Hong et al.
CANCER CELL (2020)
Inefficient CAR-proximal signaling blunts antigen sensitivity
Venugopal Gudipati et al.
NATURE IMMUNOLOGY (2020)
Multiple Disulfide-Bonded States of Native Proteins: Estimate of Number Using Probabilities of Disulfide Bond Formation
Philip J. Hogg
MOLECULES (2020)
The CAR T-Cell Mechanoimmunology at a Glance
Rui Li et al.
ADVANCED SCIENCE (2020)
How does T cell receptor clustering impact on signal transduction?
Jesse Goyette et al.
JOURNAL OF CELL SCIENCE (2019)
Clinical lessons learned from the first leg of the CAR T cell journey
Robbie G. Majzner et al.
NATURE MEDICINE (2019)
Crystal structure of murine 4-1BB and its interaction with 4-1BBL support a role for galectin-9 in 4-1BB signaling
Aruna Bitra et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2018)
Chimeric antigen receptor T-cell therapies for lymphoma
Jennifer N. Brudno et al.
NATURE REVIEWS CLINICAL ONCOLOGY (2018)
Chimeric Antigen Receptor Therapy
Carl H. June et al.
NEW ENGLAND JOURNAL OF MEDICINE (2018)
Chimeric antigen receptor T cells form nonclassical and potent immune synapses driving rapid cytotoxicity
A. J. Davenport et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2018)
Chemistry and Enzymology of Disulfide Cross-Linking in Proteins
Deborah Fass et al.
CHEMICAL REVIEWS (2018)
Incorporation of a hinge domain improves the expansion of chimeric antigen receptor T cells
Le Qin et al.
JOURNAL OF HEMATOLOGY & ONCOLOGY (2017)
Function of Novel Anti-CD19 Chimeric Antigen Receptors with Human Variable Regions Is Affected by Hinge and Transmembrane Domains
Leah Alabanza et al.
MOLECULAR THERAPY (2017)
Human primary liver cancer-derived organoid cultures for disease modeling and drug screening
Laura Broutier et al.
NATURE MEDICINE (2017)
An intermolecular FRET sensor detects the dynamics of T cell receptor clustering
Yuanqing Ma et al.
NATURE COMMUNICATIONS (2017)
IgY: a key isotype in antibody evolution
Xiaoying Zhang et al.
BIOLOGICAL REVIEWS (2017)
A DNA-Based T Cell Receptor Reveals a Role for Receptor Clustering in Ligand Discrimination
Marcus J. Taylor et al.
CELL (2017)
CAR-T Cell Therapy for Lymphoma
Carlos A. Ramos et al.
ANNUAL REVIEW OF MEDICINE, VOL 67 (2016)
Bifunctional αHER2/CD3 RNA-engineered CART-like human T cells specifically eliminate HER2+ gastric cancer
Feifei Luo et al.
CELL RESEARCH (2016)
Targeting of Tumor-Associated Glycoforms of MUC1 with CAR T Cells
John Maher et al.
IMMUNITY (2016)
Driving CAR T-cells forward
Hollie J. Jackson et al.
NATURE REVIEWS CLINICAL ONCOLOGY (2016)
Functional role of T-cell receptor nanoclusters in signal initiation and antigen discrimination
Sophie V. Pageon et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2016)
Fine-tuning the CAR spacer improves T-cell potency
Norihiro Watanabe et al.
ONCOIMMUNOLOGY (2016)
Chimeric Antigen Receptors With Mutated IgG4 Fc Spacer Avoid Fc Receptor Binding and Improve T Cell Persistence and Antitumor Efficacy
Mahesh Jonnalagadda et al.
MOLECULAR THERAPY (2015)
4-1BB costimulation ameliorates T cell exhaustion induced by tonic signaling of chimeric antigen receptors
Adrienne H. Long et al.
NATURE MEDICINE (2015)
Rational development and characterization of humanized anti-EGFR variant III chimeric antigen receptor T cells for glioblastoma
Laura A. Johnson et al.
SCIENCE TRANSLATIONAL MEDICINE (2015)
Engineering CAR-T cells: Design concepts
Shivani Srivastava et al.
TRENDS IN IMMUNOLOGY (2015)
The Nonsignaling Extracellular Spacer Domain of Chimeric Antigen Receptors Is Decisive for In Vivo Antitumor Activity
Michael Hudecek et al.
CANCER IMMUNOLOGY RESEARCH (2015)
ICOS-based chimeric antigen receptors program bipolar TH17/TH1 cells
Sonia Guedan et al.
BLOOD (2014)
Targeting Fibroblast Activation Protein in Tumor Stroma with Chimeric Antigen Receptor T Cells Can Inhibit Tumor Growth and Augment Host Immunity without Severe Toxicity
Liang-Chuan S. Wang et al.
CANCER IMMUNOLOGY RESEARCH (2014)
The Basic Principles of Chimeric Antigen Receptor Design
Michel Sadelain et al.
CANCER DISCOVERY (2013)
Immunological synapse and microclusters: the site for recognition and activation of T cells
Takashi Saito et al.
CURRENT OPINION IN IMMUNOLOGY (2006)
The role of extracellular spacer regions in the optimal design of chimeric immune receptors - Evaluation of four different scFvs and antigens
RD Guest et al.
JOURNAL OF IMMUNOTHERAPY (2005)