相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。New aspects of amino acid metabolism in cancer
Lisa Vettore et al.
BRITISH JOURNAL OF CANCER (2020)
Serine Catabolism Feeds NADH when Respiration Is Impaired
Lifeng Yang et al.
CELL METABOLISM (2020)
Scoulerine promotes cell viability reduction and apoptosis by activating ROS-dependent endoplasmic reticulum stress in colorectal cancer cells
Jiaxun Tian et al.
CHEMICO-BIOLOGICAL INTERACTIONS (2020)
Cancer proteome and metabolite changes linked to SHMT2
Jiefei Tong et al.
PLOS ONE (2020)
AICAr suppresses cell proliferation by inducing NTP and dNTP pool imbalances in acute lymphoblastic leukemia cells
Lijuan Du et al.
FASEB JOURNAL (2019)
AICAR Induces Apoptosis and Inhibits Migration and Invasion in Prostate Cancer Cells Through an AMPK/mTOR-Dependent Pathway
Chia-Cheng Su et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2019)
Metabolic reprogramming for cancer cells and their microenvironment: Beyond the Warburg Effect
Linchong Sun et al.
BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER (2018)
Serine Catabolism by SHMT2 Is Required for Proper Mitochondrial Translation Initiation and Maintenance of Formylmethionyl-tRNAs
Denise R. Minton et al.
MOLECULAR CELL (2018)
Aspartate is a limiting metabolite for cancer cell proliferation under hypoxia and in tumours
Javier Garcia-Bermudez et al.
NATURE CELL BIOLOGY (2018)
Mitochondrial translation requires folate-dependent tRNA methylation
Raphael J. Morscher et al.
NATURE (2018)
Deacetylation of serine hydroxymethyl-transferase 2 by SIRT3 promotes colorectal carcinogenesis
Zhen Wei et al.
NATURE COMMUNICATIONS (2018)
SHMT2 Desuccinylation by SIRT5 Drives Cancer Cell Proliferation
Xin Yang et al.
CANCER RESEARCH (2018)
Human SHMT inhibitors reveal defective glycine import as a targetable metabolic vulnerability of diffuse large B-cell lymphoma
Gregory S. Ducker et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2017)
Serine and Functional Metabolites in Cancer
Alice C. Newman et al.
TRENDS IN CELL BIOLOGY (2017)
Proline metabolism supports metastasis formation and could be inhibited to selectively target metastasizing cancer cells
Ilaria Elia et al.
NATURE COMMUNICATIONS (2017)
Oxidative stress-induced apoptosis in granulosa cells involves JNK, p53 and Puma
Hongyan Yang et al.
ONCOTARGET (2017)
The KMT1A-GATA3-STAT3 Circuit Is a Novel Self-Renewal Signaling of Human Bladder Cancer Stem Cells
Zhao Yang et al.
CLINICAL CANCER RESEARCH (2017)
One-carbon metabolism in cancer
Alice C. Newman et al.
BRITISH JOURNAL OF CANCER (2017)
Rational Design of Selective Allosteric Inhibitors of PHGDH and Serine Synthesis with Anti-tumor Activity
Qian Wang et al.
CELL CHEMICAL BIOLOGY (2017)
Reprogramming of glucose, fatty acid and amino acid metabolism for cancer progression
Zhaoyong Li et al.
CELLULAR AND MOLECULAR LIFE SCIENCES (2016)
A pyrazolopyran derivative preferentially inhibits the activity of human cytosolic serine hydroxymethyltransferase and induces cell death in lung cancer cells
Marina Marani et al.
ONCOTARGET (2016)
Differential 3-bromopyruvate inhibition of cytosolic and mitochondrial human serine hydroxymethyltransferase isoforms, key enzymes in cancer metabolic reprogramming
Alessandro Paiardini et al.
BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS (2016)
Metabolic phenotype of bladder cancer
Francesco Massari et al.
CANCER TREATMENT REVIEWS (2016)
Reversal of Cytosolic One-Carbon Flux Compensates for Loss of the Mitochondrial Folate Pathway (vol 23, pg 1140, 2016)
Gregory S. Ducker et al.
CELL METABOLISM (2016)
Serine Metabolism Supports the Methionine Cycle and DNA/RNA Methylation through De Novo ATP Synthesis in Cancer Cells
Oliver D. K. Maddocks et al.
MOLECULAR CELL (2016)
A PHGDH inhibitor reveals coordination of serine synthesis and one-carbon unit fate
Michael E. Pacold et al.
NATURE CHEMICAL BIOLOGY (2016)
Prognostic and therapeutic value of mitochondrial serine hydroxyl-methyltransferase 2 as a breast cancer biomarker
Lahong Zhang et al.
ONCOLOGY REPORTS (2016)
Identification of a small molecule inhibitor of 3-phosphoglycerate dehydrogenase to target serine biosynthesis in cancers
Edouard Mullarky et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2016)
Major apoptotic mechanisms and genes involved in apoptosis
Yagmur Kiraz et al.
TUMOR BIOLOGY (2016)
Downregulating serine hydroxymethyltransferase 2 (SHMT2) suppresses tumorigenesis in human hepatocellular carcinoma
Chern Chiuh Woo et al.
ONCOTARGET (2016)
Downregulation of phosphoglycerate dehydrogenase inhibits proliferation and enhances cisplatin sensitivity in cervical adenocarcinoma cells by regulating Bcl-2 and caspase-3
Zhang Jing et al.
CANCER BIOLOGY & THERAPY (2015)
cMyc-mediated activation of serine biosynthesis pathway is critical for cancer progression under nutrient deprivation conditions
Linchong Sun et al.
CELL RESEARCH (2015)
SHMT2 drives glioma cell survival in ischaemia but imposes a dependence on glycine clearance
Dohoon Kim et al.
NATURE (2015)
Amino acid management in cancer
Zhi-Yang Tsun et al.
SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY (2015)
PSAT1 regulates cyclin D1 degradation and sustains proliferation of non-small cell lung cancer cells
Yi Yang et al.
INTERNATIONAL JOURNAL OF CANCER (2015)
Comparative Oncogenomics Identifies PSMB4 and SHMT2 as Potential Cancer Driver Genes
Genee Y. Lee et al.
CANCER RESEARCH (2014)
SHMT1 knockdown induces apoptosis in lung cancer cells by causing uracil misincorporation
A. Paone et al.
CELL DEATH & DISEASE (2014)
Integrated Omic analysis of lung cancer reveals metabolism proteome signatures with prognostic impact
Lei Li et al.
NATURE COMMUNICATIONS (2014)
Serine Catabolism Regulates Mitochondrial Redox Control during Hypoxia
Jiangbin Ye et al.
CANCER DISCOVERY (2014)
Serine, but Not Glycine, Supports One-Carbon Metabolism and Proliferation of Cancer Cells
Christiaan F. Labuschagne et al.
CELL REPORTS (2014)
Oxidative stress: the mitochondria-dependent and mitochondria-independent pathways of apoptosis
Krishnendu Sinha et al.
ARCHIVES OF TOXICOLOGY (2013)
Regulation of apoptosis by Bcl-2 cysteine oxidation in human lung epithelial cells
Sudjit Luanpitpong et al.
MOLECULAR BIOLOGY OF THE CELL (2013)
Genome engineering using the CRISPR-Cas9 system
F. Ann Ran et al.
NATURE PROTOCOLS (2013)
Metabolite Profiling Identifies a Key Role for Glycine in Rapid Cancer Cell Proliferation
Mohit Jain et al.
SCIENCE (2012)
Mouse Genetics Suggests Cell-Context Dependency for Myc-Regulated Metabolic Enzymes during Tumorigenesis
Lisa M. Nilsson et al.
PLOS GENETICS (2012)
Enhanced serine production by bone metastatic breast cancer cells stimulates osteoclastogenesis
Sirkku Pollari et al.
BREAST CANCER RESEARCH AND TREATMENT (2011)
Phosphoglycerate dehydrogenase diverts glycolytic flux and contributes to oncogenesis
Jason W. Locasale et al.
NATURE GENETICS (2011)
Reactive oxygen species (ROS) control the expression of Bcl-2 family proteins by regulating their phosphorylation and ubiquitination
DC Li et al.
CANCER SCIENCE (2004)
Analysis of the composition, assembly kinetics and activity of native Apaf-1 apoptosomes
MM Hill et al.
EMBO JOURNAL (2004)
A functional screen for Myc-responsive genes reveals serine hydroxymethyltransferase, a major source of the one-carbon unit for cell metabolism
MA Nikiforov et al.
MOLECULAR AND CELLULAR BIOLOGY (2002)