期刊
CANCER CELL INTERNATIONAL
卷 22, 期 1, 页码 -出版社
BMC
DOI: 10.1186/s12935-022-02529-7
关键词
SNHG17; lncRNA; Cancer; Gene regulation; Diagnosis; Prognosis
类别
资金
- National Natural Science Foundation of China [82072591, 81871871, 81703056]
- Key Research and Development plan (Social Development) of the Science and Technology Department of Jiangsu Province [BE2019760]
- Medical Innovation Team Foundation of the Jiangsu Provincial Enhancement Health Project [CXTDA2017021]
- 123 advantageous disciplines, core technologies and 789 excellent talent training plan of the Second Affiliated Hospital of Nanjing Medical University [789ZYRC202090148]
This review summarizes the studies on SNHG17 in recent years, highlighting its high expression in various tumors and its potential impact on the biological function and clinical applications of tumor cells.
Many studies in recent years have found that dysregulation of long non-coding RNAs (lncRNAs) can contribute to disease. Small nucleolar RNA host gene 17 (SNHG17) is a novel cancer-related lncRNA of the SNHG family which is highly expressed in various tumors and may exert oncogenic functions. Several studies have demonstrated that SNHG17 is closely related to the proliferation, migration, invasion, apoptosis, and chemical drug resistance of tumor cells, and clinical studies have found an association between high SNHG17 expression and poor prognosis. In this review, we summarize relevant studies investigating SNHG17, focusing on its biological function as well as its potential value for clinical applications.
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