Tracking down tumor-specific T cells

Two papers published in this edition of Cancer Cell (Zheng et al., 2022 and Veatch et al., 2022) provide an elegant illustration of how single-cell sequencing can be used to define a molecular phenotype which identifies tumor-specific T cells.

Automated summary

This article discusses two papers published in Cancer Cell (Zheng et al., 2022 and Veatch et al., 2022) that demonstrate the application of single-cell sequencing in defining a molecular phenotype to identify tumor-specific T cells.