期刊
BUILDING AND ENVIRONMENT
卷 216, 期 -, 页码 -出版社
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.buildenv.2022.108983
关键词
Thermal sensation; Thermal comfort; S-IgE concentration; Respiratory mucosal immunity; Health
资金
- National Natural Science Foundation of China [52108080]
This study investigates the link between temperature-induced comfort and salivary secretory immunoglobulin E (S-IgE), a biomarker used to assess respiratory mucosal immunity. The findings suggest that the highest S-IgE concentration occurs at a temperature close to the thermal neutral temperature and that prolonged exposure to cold and heat can increase S-IgE concentration, potentially enhancing respiratory mucosal immunity.
The purpose of this study is to investigate the link between temperature-induced comfort and salivary secretory immunoglobulin E (S-IgE), a biomarker used to assess respiratory mucosal immunity. Our findings revealed that the highest S-IgE concentration occurred at 24 degrees C, close to the thermal neutral temperature of 22.7 degrees C in the thermal neutral temperature range of 21.4-26.9 degrees C, regardless of exposure time (5 or 30 min); However, after 60 min of exposure, when the ambient temperature increased from 21 to 33 degrees C, the subjects' average thermal sensation vote (TSV) and S-IgE concentration gradually increased by 3.2 units and 62.8%, respectively, compared to 21 degrees C; Moreover, as the TSV increased from slightly cool to warm, the S-IgE concentration corresponding to the TSV (+1.5, +3] and [-3, -1.5) increased by 60.6% and 11.4%, respectively, compared to [-1.5, -0.5) and (+0.5, +1.5], respectively. We propose that comfortable ambient temperature can only increase the concentration of S-IgE for a short time (30 min), while prolonged cold and heat exposure (60 min) is more conducive to increasing the S-IgE concentration, which may improve respiratory mucosa immunity to some extent.
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