4.7 Article

Transcriptomic characterization of the molecular mechanisms induced by RGMa during skeletal muscle nuclei accretion and hypertrophy

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Summary: The study demonstrates the important role of repulsive guidance molecule a (RGMa) in muscle cell growth and differentiation, particularly in promoting cell fusion; RGMa induces cell fusion in skeletal muscle cells via the neogenin receptor, while not inhibiting BMP signaling.

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