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Juan Xiong et al.
JOURNAL OF NATURAL PRODUCTS (2018)
Total Synthesis, Biological Evaluation, and Target Identification of Rare Abies Sesquiterpenoids
Dexter C. Davis et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2018)
(-)- and (+)-Securidanes A and B, Natural Triarylmethane Enantiomers: Structure and Bioinspired Total Synthesis
B. Zhou et al.
RESEARCH (2018)
Selectivity, cell permeability and oral availability studies of novel bromophenol derivative HPN as protein tyrosine phosphatase 1B inhibitor
Jiao Luo et al.
BRITISH JOURNAL OF PHARMACOLOGY (2018)
New neo-lignan from Acanthopanax senticosus with protein tyrosine phosphatase 1B inhibitory activity
Jia-Lin Li et al.
ARCHIVES OF PHARMACAL RESEARCH (2017)
Discovery of Bisindole as a Novel Scaffold for Protein Tyrosine Phosphatase 1B Inhibitors
Changcheng Jing et al.
ARCHIV DER PHARMAZIE (2017)
Prunin is a highly potent flavonoid from Prunus davidiana stems that inhibits protein tyrosine phosphatase 1B and stimulates glucose uptake in insulin-resistant HepG2 cells
Hyun Ah Jung et al.
ARCHIVES OF PHARMACAL RESEARCH (2017)
Promising Inhibitory Effects of Anthraquinones, Naphthopyrone, and Naphthalene Glycosides, from Cassia obtusifolia on α-Glucosidase and Human Protein Tyrosine Phosphatases 1B
Hyun Ah Jung et al.
MOLECULES (2017)
Design, synthesis and biological evaluation of uncharged catechol derivatives as selective inhibitors of PTP1B
Xiang-Qian Li et al.
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (2017)
A dioxidovanadium (V) complex of NNO-donor Schiff base as a selective inhibitor of protein tyrosine phosphatase 1B: Synthesis, characterization, and biological activities
Yuqi Jia et al.
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (2017)
Discovery and evaluation of the hybrid of bromophenol and saccharide as potent and selective protein tyrosine phosphatase 1B inhibitors
Renshuai Zhang et al.
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (2017)
Discovery of 4-[(5-arylidene-4-oxothiazolidin-3-yl)methyl]benzoic acid derivatives active as novel potent allosteric inhibitors of protein tyrosine phosphatase 1B: In silico studies and in vitro evaluation as insulinomimetic and anti-inflammatory agents
Rosaria Ottana et al.
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (2017)
New amides from seeds of Silybum marianum with potential antioxidant and antidiabetic activities
Ning-bo Qin et al.
FITOTERAPIA (2017)
Four new neolignans isolated from Eleutherococcus senticosus and their protein tyrosine phosphatase 1B inhibitory activity (PTP1B)
Le Zhang et al.
FITOTERAPIA (2017)
Chrodrimanins O-S from the fungus Penicillium. sp SCS-KFD09 isolated from a marine worm, Sipunculusnudus
Fan-Dong Kong et al.
FITOTERAPIA (2017)
Xanthones from the twigs of Garcinia oblongifolia and their antidiabetic activity
Binh T. D. Trinh et al.
FITOTERAPIA (2017)
Isoprenylated phenolic compounds with PTP1B inhibition from Morus alba
Qing-Hua Huang et al.
FITOTERAPIA (2017)
Punicalagin, a PTP1B inhibitor, induces M2c phenotype polarization via up-regulation of HO-1 in murine macrophages
Xiaolong Xu et al.
FREE RADICAL BIOLOGY AND MEDICINE (2017)
Identification of Anthocyanins from Four Kinds of Berries and Their Inhibition Activity to α-Glycosidase and Protein Tyrosine Phosphatase 1B by HPLC FT-ICR MS/MS
Ting Xiao et al.
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY (2017)
Structural and Stereochemical Studies of Laurokamurols A-C, Uncommon Bis-sesquiterpenoids from the Chinese Red Alga Laurencia okamurai Yamada
Xiao-Lu Li et al.
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY (2017)
Further New Gypenosides from Jiaogulan (Gynostemma pentaphyllum)
Jun Wang et al.
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY (2017)
Potential of Polygonum cuspidatum Root as an Antidiabetic Food: Dual High-Resolution α-Glucosidase and PTP1B Inhibition Profiling Combined with HPLC-HRMS and NMR for Identification of Antidiabetic Constituents
Yong Zhao et al.
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY (2017)
A 2,4′-linked tetrahydroxanthone dimer with protein tyrosine phosphatase 1B inhibitory activity from the Okinawan freshwater Aspergillus sp.
Henki Rotinsulu et al.
JOURNAL OF ANTIBIOTICS (2017)
Biphenyl ether derivatives with protein tyrosine phosphatase 1B inhibitory activity from the freshwater fungus Phoma sp.
Deiske A. Sumilat et al.
JOURNAL OF ANTIBIOTICS (2017)
Concise synthesis and PTP1B inhibitory activity of (R)- and (S)-dihydroresorcylide
Cheng-Shi Jiang et al.
JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH (2017)
A strategy based on gas chromatography-mass spectrometry and virtual molecular docking for analysis and prediction of bioactive composition in natural product essential oil
Haiyang Wang et al.
JOURNAL OF CHROMATOGRAPHY A (2017)
Inhibition of protein tyrosine phosphatase (PTP1B) and α-glucosidase by geranylated flavonoids from Paulownia tomentosa
Yeong Hun Song et al.
JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY (2017)
Bioactive alkaloids from the aerial parts of Houttuynia cordata
Qinge Ma et al.
JOURNAL OF ETHNOPHARMACOLOGY (2017)
In vitro anti-diabetic activity of flavonoids and pheophytins from Allophylus cominia Sw. on PTP1B, DPPIV, alpha-glucosidase and alpha-amylase enzymes
D. G. Semaan et al.
JOURNAL OF ETHNOPHARMACOLOGY (2017)
An anti-mycobacterial bisfunctionalized sphingolipid and new bromopyrrole alkaloid from the Indonesian marine sponge Agelas sp.
Delfly B. Abdjul et al.
JOURNAL OF NATURAL MEDICINES (2017)
Meroterpenoids with Protein Tyrosine Phosphatase 1B Inhibitory Activity from a Hyrtios sp Marine Sponge
Jie Wang et al.
JOURNAL OF NATURAL PRODUCTS (2017)
Glycybridins A-K, Bioactive Phenolic Compounds from Glycyrrhiza glabra
Kai Li et al.
JOURNAL OF NATURAL PRODUCTS (2017)
Camellianols A-G, Barrigenol-like Triterpenoids with PTP1B Inhibitory Effects from the Endangered Ornamental Plant Camellia crapnelliana
Juan Xiong et al.
JOURNAL OF NATURAL PRODUCTS (2017)
Phloroglucinol Derivatives with Protein Tyrosine Phosphatase 1B Inhibitory Activities from Eugenia jambolana Seeds
Feifei Liu et al.
JOURNAL OF NATURAL PRODUCTS (2017)
Trivaric acid, a new inhibitor of PTP1b with potent beneficial effect on diabetes
Wenlong Sun et al.
LIFE SCIENCES (2017)
Asperentin B, a New Inhibitor of the Protein Tyrosine Phosphatase 1B
Jutta Wiese et al.
MARINE DRUGS (2017)
α-Glucosidase and Protein Tyrosine Phosphatase 1B Inhibitory Activity of Plastoquinones from Marine Brown Alga Sargassum serratifolium
Md. Yousof Ali et al.
MARINE DRUGS (2017)
PTP1B Inhibitors from the Entomogenous Fungi Isaria fumosorosea
Jun Zhang et al.
MOLECULES (2017)
Potential of Icariin Metabolites from Epimedium koreanum Nakai as Antidiabetic Therapeutic Agents
Da Hye Kim et al.
MOLECULES (2017)
Rhodomollacetals A-C, PTP1B Inhibitory Diterpenoids with a 2,3:5,6-Di-seco-grayanane Skeleton from the Leaves of Rhododendron molle
Junfei Zhou et al.
ORGANIC LETTERS (2017)
Oleanane triterpenes with protein tyrosine phosphatase 1B inhibitory activity from aerial parts of Lantana camara collected in Indonesia and Japan
Delfly B. Abdjul et al.
PHYTOCHEMISTRY (2017)
Characterization of the inhibitory activity of natural tanshinones from Salvia miltiorrhiza roots on protein tyrosine phosphatase 1B
Da Hye Kim et al.
CHEMICO-BIOLOGICAL INTERACTIONS (2017)
α-Methyl artoflavanocoumarin from Juniperus chinensis exerts anti-diabetic effects by inhibiting PTP1B and activating the PI3K/Akt signaling pathway in insulin-resistant HepG2 cells
Hee Jin Jung et al.
ARCHIVES OF PHARMACAL RESEARCH (2017)
Novel Non-carboxylate Benzoylsulfonamide-Based Protein Tyrosine Phosphatase 1B Inhibitors with Non-competitive Actions
Ko Morishita et al.
CHEMICAL & PHARMACEUTICAL BULLETIN (2017)
Benzyl Mono-P-Fluorophosphonate and Benzyl Penta-P-Fluorophosphate Anions Are Physiologically Stable Phosphotyrosine Mimetics and Inhibitors of Protein Tyrosine Phosphatases
Stefan Wagner et al.
CHEMISTRY-A EUROPEAN JOURNAL (2017)
PTP1B inhibitors from the seeds of Iris sanguinea and their insulin mimetic activities via AMPK and ACC phosphorylation
Jun Li Yang et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2017)
Polycyclic phloroglucinols as PTP1B inhibitors from Hypericum longistylum: Structures, PTP1B inhibitory activities, and interactions with PTP1B
Xiangrong Cao et al.
BIOORGANIC CHEMISTRY (2017)
Ellagitannin and flavonoid constituents from Agrimonia pilosa Ledeb. with their protein tyrosine phosphatase and acetylcholinesterase inhibitory activities
Duc Hung Nguyen et al.
BIOORGANIC CHEMISTRY (2017)
PTP1B inhibitors from Selaginella tamariscina (Beauv.) Spring and their kinetic properties and molecular docking simulation
Duc Dat Le et al.
BIOORGANIC CHEMISTRY (2017)
Anti-diabetic xanthones from the bark of Garcinia xanthochymus
Chi N. Nguyen et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2017)
Design, synthesis, in silico and in vitro evaluation of thiophene derivatives: A potent tyrosine phosphatase 1B inhibitor and anticancer activity
Kali Charan Gulipalli et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2017)
Screening for bioactive natural products from a 67-compound library of Glycyrrhiza inflata
Yan Lin et al.
BIOORGANIC & MEDICINAL CHEMISTRY (2017)
Synthesis, biological evaluation and in silico studies of 5-(3-methoxybenzylidene)thiazolidine-2,4-dione analogues as PTP1B inhibitors
Manoj Kumar Mahapatra et al.
BIOORGANIC CHEMISTRY (2017)
Serendipitous discovery of light-induced (In Situ) formation of an Azo-bridged dimeric sulfonated naphthol as a potent PTP1B inhibitor
Robert D. Bongard et al.
BMC BIOCHEMISTRY (2017)
Y-shaped bis-arylethenesulfonic acid esters: Potential potent and membrane permeable protein tyrosine phosphatase 1B inhibitors
Fengzhi Yang et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2017)
Competitive protein tyrosine phosphatase 1B (PTP1B) inhibitors, prenylated caged xanthones from Garcinia hanburyi and their inhibitory mechanism
Xue Fei Tan et al.
BIOORGANIC & MEDICINAL CHEMISTRY (2017)
Protein tyrosine phosphatase 1B inhibitors as antidiabetic agents - A brief review
Mansi Verma et al.
BIOORGANIC CHEMISTRY (2017)
Furanoterpenes, new types of protein tyrosine phosphatase 1B inhibitors, from two Indonesian marine sponges, Ircinia and Spongia spp.
Delfly B. Abdjul et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2017)
A tetramic acid derivative with protein tyrosine phosphatase 1B inhibitory activity and a new nortriterpene glycoside from the Indonesian marine sponge Petrosia sp.
Wilmar Maarisit et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2017)
Rational design, synthesis, and structure-activity relationships of 5-amino-1H-pyrazole-4-carboxylic acid derivatives as protein tyrosine phosphatase 1B inhibitors
Sujay Basu et al.
BIOORGANIC & MEDICINAL CHEMISTRY (2017)
Discovery of core-structurally novel PTP1B inhibitors with specific selectivity containing oxindole-fused spirotetrahydrofurochroman by one-pot reaction
Suzhen Dong et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2017)
A new bioactive steroidal ketone from the South China Sea sponge Xestospongia testudinaria
Wen-Fei He et al.
JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH (2016)
Protein tyrosine phosphatase 1B inhibitors isolated from Artemisia roxburghiana
Muhammad Raza Shah et al.
JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY (2016)
Protein tyrosine phosphatase 1B (PTP1B) inhibitory activity and glucosidase inhibitory activity of compounds isolated from Agrimonia pilosa
Braham Na et al.
PHARMACEUTICAL BIOLOGY (2016)
Quantitation of phenylpropanoids and iridoids in insulin-sensitising extracts of Leonurus sibiricus L. (Lamiaceae)
Anna Pitschmann et al.
PHYTOCHEMICAL ANALYSIS (2016)
Inhibitory evaluation of oligonol on α-glucosidase, protein tyrosine phosphatase 1B, cholinesterase, and β-secretase 1 related to diabetes and Alzheimer's disease
Jae Sue Choi et al.
ARCHIVES OF PHARMACAL RESEARCH (2016)
Promising anti-diabetic potential of capillin and capillinol isolated from Artemisia capillaris
Md. Nurul Islam et al.
ARCHIVES OF PHARMACAL RESEARCH (2016)
A dimeric urea of the bisabolene sesquiterpene from the Okinawan marine sponge Axinyssa sp inhibits protein tyrosine phosphatase 1B activity in Huh-7 human hepatoma cells
Delfly B. Abdjul et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2016)
Novel chromenedione derivatives displaying inhibition of protein tyrosine phosphatase 1B (PTP1B) from Flemingia philippinensis
Yan Wang et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2016)
Design, synthesis and in vitro activity of phidianidine B derivatives as novel PTP1B inhibitors with specific selectivity
Li Zhang et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2016)
In vitro and in silico PTP-1B inhibition and in vivo antidiabetic activity of semisynthetic moronic acid derivatives
Litzia Ceron-Romero et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2016)
Novel Imbricatolic acid derivatives as protein tyrosine phosphatase-1B inhibitors: Design, synthesis, biological evaluation and molecular docking
Mohammad Faheem Khan et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2016)
A novel protein tyrosine phosphatase 1B inhibitor with therapeutic potential for insulin resistance
Xiaolin Zhang et al.
BRITISH JOURNAL OF PHARMACOLOGY (2016)
Selective Inhibition of PTP1B by Vitalboside A from Syzygium cumini Enhances Insulin Sensitivity and Attenuates Lipid Accumulation Via Partial Agonism to PPARγ: In Vitro and In Silico Investigation
Gopal Thiyagarajan et al.
CHEMICAL BIOLOGY & DRUG DESIGN (2016)
PTP1B, α-glucosidase, and DPP-IV inhibitory effects for chromene derivatives from the leaves of Smilax china L.
Bing Tian Zhao et al.
CHEMICO-BIOLOGICAL INTERACTIONS (2016)
Coumarins from Angelica decursiva inhibit α-glucosidase activity and protein tyrosine phosphatase 1B
Md Yousof Ali et al.
CHEMICO-BIOLOGICAL INTERACTIONS (2016)
Discovery of novel, high potent, ABC type PTP1B inhibitors with TCPTP selectivity and cellular activity
Peihong Liu et al.
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (2016)
Design and synthesis of new potent PTP1B inhibitors with the skeleton of 2-substituted imino-3-substituted-5-heteroarylidene-1,3-thiazolidine-4-one: Part I
Ge Meng et al.
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (2016)
High-resolution PTP1S inhibition profiling combined with high-performance liquid chromatography-high-resolution mass spectrometry-solid-phase extraction-nuclear magnetic resonance spectroscopy: Proof-of-concept and antidiabetic constituents in crude extract of Eremophila lucida
Yousof Tahtah et al.
FITOTERAPIA (2016)
New sesquiterpenoids from the edible mushroom Pleurotus cystidiosus and their inhibitory activity against α-glucosidase and PTP1B
Qiao-Qiao Tao et al.
FITOTERAPIA (2016)
Secondary metabolites from the flower buds of Lonicera japonica and their in vitro anti-diabetic activities
Zhixiang Liu et al.
FITOTERAPIA (2016)
Rapid Identification of Flavonoid Constituents Directly from PTP1B Inhibitive Extract of Raspberry (Rubus idaeus L.) Leaves by HPLC-ESI-QTOF-MS-MS
Zhuan-Hong Li et al.
JOURNAL OF CHROMATOGRAPHIC SCIENCE (2016)
Identification and evaluation of magnolol and chrysophanol as the principle protein tyrosine phosphatase-1B inhibitory compounds in a Kampo medicine, Masiningan
Toshihisa Onoda et al.
JOURNAL OF ETHNOPHARMACOLOGY (2016)
Protein tyrosine phosphatase 1B and α-glucosidase inhibitory activities of Pueraria lobata root and its constituents
Su Hui Seong et al.
JOURNAL OF ETHNOPHARMACOLOGY (2016)
Structure and Configuration of Phosphoeleganin, a Protein Tyrosine Phosphatase 1B Inhibitor from the Mediterranean Ascidian Sidnyum elegans
Concetta Imperatore et al.
JOURNAL OF NATURAL PRODUCTS (2016)
Sesquiterpene Hydroquinones with Protein Tyrosine Phosphatase 1B Inhibitory Activities from a Dysidea sp Marine Sponge Collected in Okinawa
Delfly B. Abdjul et al.
JOURNAL OF NATURAL PRODUCTS (2016)
Eucarobustols A-I, Conjugates of Sesquiterpenoids and Acylphloroglucinols from Eucalyptus robusta
Yang Yu et al.
JOURNAL OF NATURAL PRODUCTS (2016)
Bioactive Constituents of Glycyrrhiza uralensis (Licorice): Discovery of the Effective Components of a Traditional Herbal Medicine
Shuai Ji et al.
JOURNAL OF NATURAL PRODUCTS (2016)
Identification of PTP1B and α-Glucosidase Inhibitory Serrulatanes from Eremophila spp. by Combined use of Dual High-Resolution PTP1B and α-Glucosidase Inhibition Profiling and HPLC-HRMS-SPE-NMR
Sileshi G. Wubshet et al.
JOURNAL OF NATURAL PRODUCTS (2016)
Bioassay-guided isolation of an active compound with protein tyrosine phosphatase 1B inhibitory activity from Sargassum fusiforme by high-speed counter-current chromatography
Miao Wang et al.
JOURNAL OF SEPARATION SCIENCE (2016)
Design, Synthesis and Biological Evaluation of Stilbene Derivatives as Novel Inhibitors of Protein Tyrosine Phosphatase 1B
Haibing He et al.
MOLECULES (2016)
Xanthium strumarium as an Inhibitor of -Glucosidase, Protein Tyrosine Phosphatase 1, Protein Glycation and ABTS+ for Diabetic and Its Complication
Seung Hwan Hwang et al.
MOLECULES (2016)
DNA TAGS HELP THE HUNT FOR DRUGS
Asher Mullard
NATURE (2016)
An efficient strategy to enhance binding affinity and specificity of a known isozyme inhibitor
Joo-Eun Jee et al.
ORGANIC & BIOMOLECULAR CHEMISTRY (2016)
Cipacinoids A-D, Four Limonoids with Spirocyclic Skeletons from Cipadessa cinerascens
Jin-Hai Yu et al.
ORGANIC LETTERS (2016)
Structures and biological activities of triterpenes and sesquiterpenes obtained from Russula lepida
Jong-Soo Lee et al.
PHYTOCHEMISTRY (2016)
Sesquiterpenoids with PTP1B Inhibitory Activity and Cytotoxicity from the Edible Mushroom Pleurotus citrinopileatus
Qiao-Qiao Tao et al.
PLANTA MEDICA (2016)
Glucose Uptake Activities of Bis (2, 3-Dibromo-4, 5-Dihydroxybenzyl) Ether, a Novel Marine Natural Product from Red Alga Odonthaliacorymbifera with Protein Tyrosine Phosphatase 1B Inhibition, In Vitro and In Vivo
Feng Xu et al.
PLOS ONE (2016)
The potent inhibitors of protein tyrosine phosphatase 1B from the fruits of Melaleuca leucadendron
Azis Saifudin et al.
PHARMACOGNOSY RESEARCH (2016)
Anti-diabetic and anti-Alzheimer's disease activities of Angelica decursiva
Md. Yousof Ali et al.
ARCHIVES OF PHARMACAL RESEARCH (2015)
Functional properties of Claramine: A novel PTP1B inhibitor and insulin-mimetic compound
Zhaohong Qin et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2015)
Light-switched inhibitors of protein tyrosine phosphatase PTP1B based on phosphonocarbonyl phenylalanine as photoactive phosphotyrosine mimetic
Stefan Wagner et al.
BIOORGANIC & MEDICINAL CHEMISTRY (2015)
Novel, potent, selective and cellular active ABC type PTP1B inhibitors containing (methanesulfonyl-phenyl-amino)-acetic acid methyl ester phosphotyrosine mimetic
Peihong Liu et al.
BIOORGANIC & MEDICINAL CHEMISTRY (2015)
Discovery of novel, potent, selective and cellular active ADC type PTP1B inhibitors via fragment-docking-oriented de novel design
Yongli Du et al.
BIOORGANIC & MEDICINAL CHEMISTRY (2015)
Selaginellin and biflavonoids as protein tyrosine phosphatase 1B inhibitors from Selaginella tamariscina and their glucose uptake stimulatory effects
Phi-Hung Nguyen et al.
BIOORGANIC & MEDICINAL CHEMISTRY (2015)
PTP1B inhibitors from stems of Angelica keiskei (Ashitaba)
Jin-long Li et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2015)
Verruculides A and B, two new protein tyrosine phosphatase 1B inhibitors from an Indonesian ascidian-derived Penicillium verruculosume
Hiroyuki Yamazaki et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2015)
Inactivation of protein tyrosine phosphatases by dietary isothiocyanates
Sarah M. Lewis et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2015)
Strongylophorines, new protein tyrosine phosphatase 1B inhibitors, from the marine sponge Strongylophora strongilata collected at Iriomote Island
Jong-Soo Lee et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2015)
Two new protein tyrosine phosphatase 1B inhibitors, hyattellactones A and B, from the Indonesian marine sponge Hyattella sp.
Delfly B. Abdjul et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2015)
Canthinone alkaloids are novel protein tyrosine phosphatase 1B inhibitors
Tatsunori Sasaki et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2015)
Design and synthesis of novel 1,2-dithiolan-4-yl benzoate derivatives as PTP1B inhibitors
Jing Chen et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2015)
Novel 2,7-Substituted (S)-1,2,3,4-Tetrahydroisoquinoline-3-carboxylic Acids: Peroxisome Proliferator-Activated Receptor γ Partial Agonists with Protein-Tyrosine Phosphatase 1B Inhibition
Kazuya Otake et al.
CHEMICAL & PHARMACEUTICAL BULLETIN (2015)
Synthesis of Novel 3-aryl-1-oxa-2,8-diazaspiro[4.5]dec-2-ene Derivatives and Their Biological Evaluation Against Protein Tyrosine Phosphatase 1B
Wen-Long Wang et al.
CHEMICAL BIOLOGY & DRUG DESIGN (2015)
Synthesis, biological evaluation and 3D-QSAR studies of imidazolidine-2,4-dione derivatives as novel protein tyrosine phosphatase 1B inhibitors
Mei-Yan Wang et al.
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (2015)
Protein tyrosine phosphatase 1B (PTP1B) inhibitory constituents from the aerial parts of Tradescantia spathacea Sw.
Quoc Hung Vo et al.
FITOTERAPIA (2015)
Structure and biosynthesis of fumosorinone, a new protein tyrosine phosphatase 1B inhibitor firstly isolated from the entomogenous fungus Isaria fumosorosea
Linxia Liu et al.
FUNGAL GENETICS AND BIOLOGY (2015)
Trichoketides A and B, two new protein tyrosine phosphatase 1B inhibitors from the marine-derived fungus Trichoderma sp.
Hiroyuki Yamazaki et al.
JOURNAL OF ANTIBIOTICS (2015)
New laurane-type sesquiterpenoids from the Chinese red alga Laurencia okamurai Yamada
Xiao-Lu Li et al.
JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH (2015)
Brominated polyunsaturated lipids with protein tyrosine phosphatase-1B inhibitory activity from Chinese marine sponge Xestospongia testudinaria
Wen-Fei He et al.
JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH (2015)
Novel stilbenes from Artocarpus nanchuanensis
Pu-Zhao Zhang et al.
JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH (2015)
pH-metric chemical speciation modeling and studies of in vitro antidiabetic effects of bis[(imidazolyl)carboxylato] oxidovanadium(IV) complexes
Isaac Z. Gundhla et al.
JOURNAL OF INORGANIC BIOCHEMISTRY (2015)
Complexes of N-hydroxyethyl-N-benzimidazolylmethylethylenediaminediacetic acid with group 12 metals and vanadium-Synthesis, structure and bioactivity of the vanadium complex
Ladislav Habala et al.
JOURNAL OF INORGANIC BIOCHEMISTRY (2015)
Structures and Biological Evaluations of Agelasines Isolated from the Okinawan Marine Sponge Agelas nakamurai
Delfly B. Abdjul et al.
JOURNAL OF NATURAL PRODUCTS (2015)
Steroidal Alkaloids from Veratrum nigrum Enhance Glucose Uptake in Skeletal Muscle Cells
ChuHyun Kang et al.
JOURNAL OF NATURAL PRODUCTS (2015)
Hydroxylated Daphniphyllum Alkaloids from Daphniphyllum himalense
Hua Zhang et al.
JOURNAL OF NATURAL PRODUCTS (2015)
Chlorabietols A-C, Phloroglucinol-Diterpene Adducts from the Chloranthaceae Plant Chloranthus oldhamii
Juan Xiong et al.
JOURNAL OF ORGANIC CHEMISTRY (2015)
Protein Tyrosine Phosphatase 1B Inhibitors from the Roots of Cudrania tricuspidata
Tran Hong Quang et al.
MOLECULES (2015)
Phytochemical Profiling and Evaluation of Pharmacological Activities of Hypericum scabrum L.
Lan Jiang et al.
MOLECULES (2015)
Two new compounds from cultures of the basidiomycete Antrodiella albocinnamomea
Zi-Ming Chen et al.
NATURAL PRODUCT RESEARCH (2015)
Phosphonate monoesters on a thiacalix[4]arene framework as potential inhibitors of protein tyrosine phosphatase 1B
Viacheslav V. Trush et al.
ORGANIC & BIOMOLECULAR CHEMISTRY (2015)
Two Enantiomeric Pairs of Meroterpenoids from Rhododendron capitatum
Hai-Bing Liao et al.
ORGANIC LETTERS (2015)
Potent protein tyrosine phosphatase 1B (PTP1B) inhibiting constituents from Anoectochilus chapaensis and molecular docking studies
Jinyan Cai et al.
PHARMACEUTICAL BIOLOGY (2015)
Aldose reductase and protein tyrosine phosphatase 1B inhibitory active compounds from Syzygium cumini seeds
Laxman Sawant et al.
PHARMACEUTICAL BIOLOGY (2015)
Diels-Alder adducts with PTP1B inhibition from Morus notabilis
Meng Wang et al.
PHYTOCHEMISTRY (2015)
Chemical Constituents of Euonymus alatus (Thunb.) Sieb. and Their PTP1B and α-Glucosidase Inhibitory Activities
Su-Yang Jeong et al.
PHYTOTHERAPY RESEARCH (2015)
BIOCHEMISTRY DNA helps build molecular libraries for drug testing
Trisha Gura
SCIENCE (2015)
Development of Novel Triazolo-Thiadiazoles from Heterogeneous Green Catalysis as Protein Tyrosine Phosphatase 1B Inhibitors
C. P. Baburajeev et al.
SCIENTIFIC REPORTS (2015)
Magnolia officinalis Extract Contains Potent Inhibitors against PTP1B and Attenuates Hyperglycemia in db/db Mice
Jing Sun et al.
BIOMED RESEARCH INTERNATIONAL (2015)
Effect of Hypericum perforatum L. Extract on Insulin Resistance and Lipid Metabolic Disorder in High-Fat-Diet Induced Obese Mice
Jin-ying Tian et al.
PHYTOTHERAPY RESEARCH (2015)
The effects of C-glycosylation of luteolin on its antioxidant, anti-Alzheimer's disease, anti-diabetic, and anti-inflammatory activities
Jae Sue Choi et al.
ARCHIVES OF PHARMACAL RESEARCH (2014)
4-Quinolone-3-carboxylic acids as cell-permeable inhibitors of protein tyrosine phosphatase 1B
Ying Zhi et al.
BIOORGANIC & MEDICINAL CHEMISTRY (2014)
Synthesis and biological evaluation of novel bis-aromatic amides as novel PTP1B inhibitors
Wen-Long Wang et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2014)
Design, synthesis and docking study of 5-(substituted benzylidene)thiazolidine-2,4-dione derivatives as inhibitors of protein tyrosine phosphatase 1B
Zengtao Wang et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2014)
Tanzawaic acid derivatives from a marine isolate of Penicillium sp (SF-6013) with anti-inflammatory and PTP1B inhibitory activities
Tran Hong Quang et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2014)
Evaluation of 147 Kampo prescriptions as novel protein tyrosine phosphatase 1B (PTP1B) inhibitory agents
Toshihisa Onoda et al.
BMC COMPLEMENTARY AND ALTERNATIVE MEDICINE (2014)
The Discovery of a Novel and Selective Inhibitor of PTP1B Over TCPTP: 3D QSAR Pharmacophore Modeling, Virtual Screening, Synthesis, and Biological Evaluation
Ying Ma et al.
CHEMICAL BIOLOGY & DRUG DESIGN (2014)
3-Phenylpropanoic Acid- Based Phosphotyrosine ( pTyr) Mimetics: Hit Evolution to a Novel Orally Active Protein Tyrosine Phosphatase 1B ( PTP1B) Inhibitor
Yan-Bo Tang et al.
CHEMMEDCHEM (2014)
Grape Seed Extracts Inhibit Platelet Aggregation by Inhibiting Protein Tyrosine Phosphatase
Joseph Wuxun Jin et al.
CLINICAL AND APPLIED THROMBOSIS-HEMOSTASIS (2014)
Norathyriol reverses obesity- and high-fat-diet-induced insulin resistance in mice through inhibition of PTP1B
Hanying Ding et al.
DIABETOLOGIA (2014)
Synthesis of oleanolic acid derivatives: In vitro, in vivo and in silico studies for PTP-1B inhibition
Juan Jose Ramirez-Espinosa et al.
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (2014)
New compounds from acid hydrolyzed products of the fruits of Momordica charantia L. and their inhibitory activity against protein tyrosine phosphatas 1B
Ke Zeng et al.
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (2014)
Synthesis, biological activity and structure-activity relationships of new benzoic acid-based protein tyrosine phosphatase inhibitors endowed with insulinomimetic effects in mouse C2C12 skeletal muscle cells
Rosaria Ottana et al.
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (2014)
Identification of novel PTP1B inhibitors by pharmacophore based virtual screening, scaffold hopping and docking
Vishal M. Balaramnavar et al.
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (2014)
PTP1B inhibitors for type 2 diabetes treatment: a patent review (2011-2014)
Akhilesh Kumar Tamrakar et al.
EXPERT OPINION ON THERAPEUTIC PATENTS (2014)
Furostanol saponins from the seeds of Allium cepa L.
Chuang-Jun Li et al.
FITOTERAPIA (2014)
Caffeoylquinic acid derivatives isolated from the aerial parts of Gynura divaricata and their yeast α-glucosidase and PTP1B inhibitory activity
Jian Chen et al.
FITOTERAPIA (2014)
Geranylated 2-arylbenzofurans from Morus alba var. tatarica and their alpha-glucosidase and protein tyrosine phosphatase 1B inhibitory activities
Ya-Long Zhang et al.
FITOTERAPIA (2014)
Bioactivity-guided chemical analysis of Melia azedarach L. (Meliaceae), displaying antidiabetic activity
Mohammad Faheem Khan et al.
FITOTERAPIA (2014)
Effects of C-glycosylation on anti-diabetic, anti-Alzheimer's disease and anti-inflammatory potential of apigenin
Jae Sue Choi et al.
FOOD AND CHEMICAL TOXICOLOGY (2014)
Vicenin 2 isolated from Artemisia capillaris exhibited potent anti-glycation properties
Md Nurul Islam et al.
FOOD AND CHEMICAL TOXICOLOGY (2014)
Bioactive Compounds from Culinary Herbs Inhibit a Molecular Target for Type 2 Diabetes Management, Dipeptidyl Peptidase IV
Allyson M. Bower et al.
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY (2014)
Two new ylangene-type sesquiterpenoids from cultures of the fungus Postia sp.
Qiong-Ying Fan et al.
JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH (2014)
New triterpenoids with protein tyrosine phosphatase 1B inhibition from Cedrela odorata
Wen-Bin Wu et al.
JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH (2014)
Thunberol, a new sterol from the Chinese brown alga Sargassum thunbergii
Wen-Fei He et al.
JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH (2014)
Racemosin C, a novel minor bisindole alkaloid with protein tyrosine phosphatase-1B inhibitory activity from the green alga Caulerpa racemosa
Hui Yang et al.
JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH (2014)
Walnut leaf extract inhibits PTP1B and enhances glucose-uptake in vitro
Anna Pitschmann et al.
JOURNAL OF ETHNOPHARMACOLOGY (2014)
Regio- and Diastereoselective Construction of α-Hydroxy-δ-amino Ester Derivatives via 1,4-Conjugate Addition of β,γ-Unsaturated N-Sulfonylimines
Lin Qiu et al.
JOURNAL OF ORGANIC CHEMISTRY (2014)
Insulin Sensitization by a Novel Partial Peroxisome Proliferator-Activated Receptor γ Agonist With Protein Tyrosine Phosphatase 1B Inhibitory Activity in Experimental Osteoporotic Rats
Masahiro Kubo et al.
JOURNAL OF PHARMACOLOGICAL SCIENCES (2014)
Recent Updates on Glucokinase Activators for the Treatment of Type 2 Diabetes Mellitus
Ajmer Singh Grewala et al.
MINI-REVIEWS IN MEDICINAL CHEMISTRY (2014)
Safranal, a novel protein tyrosine phosphatase 1B inhibitor, activates insulin signaling in C2C12 myotubes and improves glucose tolerance in diabetic KK-Ay mice
Ayumi Maeda et al.
MOLECULAR NUTRITION & FOOD RESEARCH (2014)
Design and Synthesis of Novel 2-Substituted Benzothiazole Compounds as PTP1B Inhibitors
Arun P. Chandrasekharappa et al.
LETTERS IN DRUG DESIGN & DISCOVERY (2014)
1H-2,3-Dihydroperimidine Derivatives: A New Class of Potent Protein Tyrosine Phosphatase 1B Inhibitors
Wen-Long Wang et al.
MOLECULES (2014)
Penostatin Derivatives, a Novel Kind of Protein Phosphatase 1B Inhibitors Isolated from Solid Cultures of the Entomogenous Fungus Isaria tenuipes
Yu-Peng Chen et al.
MOLECULES (2014)
New Hippolide Derivatives with Protein Tyrosine Phosphatase 1B Inhibitory Activity from the Marine Sponge Hippospongia lachne
Shu-Juan Piao et al.
MARINE DRUGS (2014)
Oleanane triterpenes as protein tyrosine phosphatase 1B (PTP1B) inhibitors from Camellia japonica
Mohammad Nasir Uddin et al.
PHYTOCHEMISTRY (2014)
Design and synthesis of paracaseolide A analogues as selective protein tyrosine phosphatase 1B inhibitors
Jian-Peng Yin et al.
ORGANIC & BIOMOLECULAR CHEMISTRY (2014)
Four Phragmalin Orthoesters from the Chinese Mangrove Xylocarpus granatum
Zhen-Fang Zhou et al.
PLANTA MEDICA (2014)
Protein Tyrosine Phosphatase 1B Inhibitory Activity of Lavandulyl Flavonoids from Roots of Sophora flavescens
Tatsunori Sasaki et al.
PLANTA MEDICA (2014)
Antidiabetic Property of Symplocos cochinchinensis Is Mediated by Inhibition of Alpha Glucosidase and Enhanced Insulin Sensitivity
Kalathookunnel Antony Antu et al.
PLOS ONE (2014)
Three novel degraded steroids from cultures of the Basidiomycete Antrodiella albocinnamomea
Zi-Ming Chen et al.
STEROIDS (2014)
Pharmacological Effects of JTT-551, a Novel Protein Tyrosine Phosphatase 1B Inhibitor, in Diet-Induced Obesity Mice
Makoto Ito et al.
JOURNAL OF DIABETES RESEARCH (2014)
Improved metabolic phenotype of hypothalamic PTP1B-deficiency is dependent upon the leptin receptor
Ryan C. Tsou et al.
MOLECULAR METABOLISM (2014)
Chromium-containing traditional Chinese medicine, Tianmai Xiaoke Tablet improves blood glucose through activating insulin-signaling pathway and inhibiting PTP1B and PCK2 in diabetic rats
Qian Zhang et al.
JOURNAL OF INTEGRATIVE MEDICINE-JIM (2014)
Kinetics and molecular docking studies of pimarane-type diterpenes as protein tyrosine phosphatase (PTP1B) inhibitors from Aralia continentalis roots
Hyun Ah Jung et al.
ARCHIVES OF PHARMACAL RESEARCH (2013)
Potent α-glucosidase and protein tyrosine phosphatase 1B inhibitors from Artemisia capillaris
Md Nurul Islam et al.
ARCHIVES OF PHARMACAL RESEARCH (2013)
Cembrane diterpenoids from the soft coral Sarcophyton trocheliophorum Marenzeller as a new class of PTP1B inhibitors
Lin-Fu Liang et al.
BIOORGANIC & MEDICINAL CHEMISTRY (2013)
Protein tyrosine phosphatase 1B inhibitory effect by dammarane-type triterpenes from hydrolyzate of total Gynostemma pentaphyllum saponins
Xiao-Shu Zhang et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2013)
Euryspongins A-C, three new unique sesquiterpenes from a marine sponge Euryspongia sp.
Hiroyuki Yamazaki et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2013)
Discovery of novel PTP1B inhibitors via pharmacophore-oriented scaffold hopping from Ertiprotafib
Jun-Zheng Liu et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2013)
The first synthesis of natural disulfide bruguiesulfurol and biological evaluation of its derivatives as a novel scaffold for PTP1B inhibitors
Jing Chen et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2013)
Design, synthesis and insulin-sensitising effects of novel PTP1B inhibitors
Yan-Bo Tang et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2013)
Evaluation of licorice flavonoids as protein tyrosine phosphatase 1B inhibitors
Wei Li et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2013)
Design and synthesis of 2-substituted benzoxazoles as novel PTP1B inhibitors
Arun P. Chandrasekharappa et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2013)
Calix[4]arene methylenebisphosphonic acids as inhibitors of protein tyrosine phosphatase 1B
Viacheslav V. Trush et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2013)
Stearic Acid Serves as a Potent Inhibitor of Protein Tyrosine Phosphatase 1B
Ayako Tsuchiya et al.
CELLULAR PHYSIOLOGY AND BIOCHEMISTRY (2013)
Effects of Newly Synthesized DCP-LA-Phospholipids on Protein Kinase C and Protein Phosphatases
Takeshi Kanno et al.
CELLULAR PHYSIOLOGY AND BIOCHEMISTRY (2013)
Free Fatty Acids Inhibit Protein Tyrosine Phosphatase 1B and Activate Akt
Eisuke Shibata et al.
CELLULAR PHYSIOLOGY AND BIOCHEMISTRY (2013)
Design and Synthesis of Imidazolidine-2,4-Dione Derivatives as Selective Inhibitors by Targeting Protein Tyrosine Phosphatase-1B Over T-Cell Protein Tyrosine Phosphatase
Ying Ma et al.
CHEMICAL BIOLOGY & DRUG DESIGN (2013)
Kinetics and molecular docking studies of an anti-diabetic complication inhibitor fucosterol from edible brown algae Eisenia bicyclis and Ecklonia stolonifera
Hyun Ah Jung et al.
CHEMICO-BIOLOGICAL INTERACTIONS (2013)
Pharmacological Inhibition of Protein Tyrosine Phosphatase 1B: A Promising Strategy for the Treatment of Obesity and Type 2 Diabetes Mellitus
E. Panzhinskiy et al.
CURRENT MEDICINAL CHEMISTRY (2013)
Discovery of novel bromophenol 3,4-dibromo-5-(2-bromo-3,4-dihydroxy-6-(isobutoxymethyl)benzyl)benzene-1,2-diol as protein tyrosine phosphatase 1B inhibitor and its anti-diabetic properties in C57BL/KsJ-db/db mice
Bo Jiang et al.
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (2013)
Design, synthesis, and biological evaluation of novel 2-ethyl-5-phenylthiazole-4-carboxamide derivatives as protein tyrosine phosphatase 1B inhibitors with improved cellular efficacy
Yue-Ting Chen et al.
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (2013)
Synthesis and biological evaluation of oleanolic acid derivatives as PTP1B inhibitors
Qing-Chao Liu et al.
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (2013)
Design, synthesis and molecular modelling studies of novel 3-acetamido-4-methyl benzoic acid derivatives as inhibitors of protein tyrosine phosphatase 1B
Monika Rakse et al.
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (2013)
Bioactive carbazole alkaloids from Murraya koenigii (L.) Spreng
Qinge Ma et al.
FITOTERAPIA (2013)
Design, Synthesis, Biological Activity and Molecular Dynamics Studies of Specific Protein Tyrosine Phosphatase 1B Inhibitors over SHP-2
Su-Xia Sun et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2013)
Synthesis and characterization of 5,7-dihydroxyflavanone derivatives as novel protein tyrosine phosphatase 1B inhibitors
Liang-Peng Sun et al.
JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY (2013)
In vitro effects of cinnamic acid derivatives on protein tyrosine phosphatase 1B
Sirichai Adisakwattana et al.
JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY (2013)
PTP1B Inhibitory Secondary Metabolites from Marine-Derived Fungal Strains Penicillium spp. and Eurotium sp.
Jae Hak Sohn et al.
JOURNAL OF MICROBIOLOGY AND BIOTECHNOLOGY (2013)
A polybromodiphenyl ether from an Indonesian marine sponge Lamellodysidea herbacea and its chemical derivatives inhibit protein tyrosine phosphatase 1B, an important target for diabetes treatment
Hiroyuki Yamazaki et al.
JOURNAL OF NATURAL MEDICINES (2013)
Protein tyrosine phosphatase 1B inhibitory activity of Indonesian herbal medicines and constituents of Cinnamomum burmannii and Zingiber aromaticum
Azis Saifudin et al.
JOURNAL OF NATURAL MEDICINES (2013)
Protein Tyrosine Phosphatase 1B (PTP1B) Inhibitors from Morinda citrifolia (Noni) and Their Insulin Mimetic Activity
Phi-Hung Nguyen et al.
JOURNAL OF NATURAL PRODUCTS (2013)
Sesquiterpenes from the Rhizomes of Curcuma heyneana
Azis Saifudin et al.
JOURNAL OF NATURAL PRODUCTS (2013)
Diphenylether Derivative as Selective Inhibitor of Protein Tyrosine Phosphatase 1B (PTP1B) Over T-cell Protein Tyrosine Phosphatase (TCPTP) Identified through Virtual Screening
M. V. V. V. Sekhar Reddy et al.
MINI-REVIEWS IN MEDICINAL CHEMISTRY (2013)
PTP1B Inhibitory and Anti-Inflammatory Effects of Secondary Metabolites Isolated from the Marine-Derived Fungus Penicillium sp JF-55
Dong-Sung Lee et al.
MARINE DRUGS (2013)
Unprecedented Diterpenoids as a PTP1B Inhibitor from the Hainan Soft Coral Sarcophyton trocheliophorum Marenzeller
Lin-Fu Liang et al.
ORGANIC LETTERS (2013)
Asperterpenoid A, a New Sesterterpenoid as an Inhibitor of Mycobacterium tuberculosis Protein Tyrosine Phosphatase B from the Culture of Aspergillus sp 16-5c
Xishan Huang et al.
ORGANIC LETTERS (2013)
X-Ray Structure of PTP1B in Complex with a New PTP1B Inhibitor
M.V.V.V. reddy et al.
PROTEIN AND PEPTIDE LETTERS (2013)
Design, Synthesis, and Biological Evaluation of Bromophenol Derivatives as Protein Tyrosine Phosphatase 1B Inhibitors
Bo Jiang et al.
ARCHIV DER PHARMAZIE (2012)
Inhibitory activity of Aralia continentalis roots on protein tyrosine phosphatase 1B and rat lens aldose reductase
Hee Jin Jung et al.
ARCHIVES OF PHARMACAL RESEARCH (2012)
Specific Inhibition of Sensitized Protein Tyrosine Phosphatase 1B (PTP1B) with a Biarsenical Probe
Oliver B. Davis et al.
BIOCONJUGATE CHEMISTRY (2012)
Novel (S)-1,2,3,4-tetrahydroisoquinoline-3-carboxylic acids: Peroxisome proliferator-activated receptor γ selective agonists with protein-tyrosine phosphatase 1B inhibition
Kazuya Otake et al.
BIOORGANIC & MEDICINAL CHEMISTRY (2012)
Synthesis of propiophenone derivatives as new class of antidiabetic agents reducing body weight in db/db mice
Atul Kumar et al.
BIOORGANIC & MEDICINAL CHEMISTRY (2012)
New prenylated isoflavonoids as protein tyrosine phosphatase 1B (PTP1B) inhibitors from Erythrina addisoniae
Phi Hung Nguyen et al.
BIOORGANIC & MEDICINAL CHEMISTRY (2012)
Discovery of di-indolinone as a novel scaffold for protein tyrosine phosphatase 1B inhibitors
Hou-ling Dai et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2012)
7-Phenyl-pyrido[2,3-d]pyrimidine-2,4-diamines: Novel and highly selective protein tyrosine phosphatase 1B inhibitors
Adrian Wai-Hing Cheung et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2012)
New diterpene furanoids from the Antarctic lichen Huea sp
Yinglan Cui et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2012)
Discovery of novel and potent heterocyclic carboxylic acid derivatives as protein tyrosine phosphatase 1B inhibitors
Sujay Basu et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2012)
Bromophenols as inhibitors of protein tyrosine phosphatase 1B with antidiabetic properties
Dayong Shi et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2012)
Rhododendric acid A, a new ursane-type PTP1B inhibitor from the endangered plant Rhododendron brachycarpum G. Don
Yeon Ho Choi et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2012)
Synthesis and biological evaluation of 4,4-dimethyl lithocholic acid derivatives as novel inhibitors of protein tyrosine phosphatase 1B
Hai-Bing He et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2012)
Discovery of potent, selective and orally bioavailable triaryl-sulfonamide based PTP1B inhibitors
Dipam Patel et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2012)
Anti-obesity and hypolipidemic effects of Rheum undulatum in high-fat diet-fed C57BL/6 mice through protein tyrosine phosphatase 1B inhibition
Woojung Lee et al.
BMB REPORTS (2012)
Indomethacin Serves as a Potential Inhibitor of Protein Phosphatases
Takeshi Kanno et al.
CELLULAR PHYSIOLOGY AND BIOCHEMISTRY (2012)
Synthesis and Biological Evaluation of 2,4,6-Trihydroxychalcone Derivatives as Novel Protein Tyrosine Phosphatase 1B Inhibitors
Liang-Peng Sun et al.
CHEMICAL BIOLOGY & DRUG DESIGN (2012)
Synthesis, Structure-Activity Relationship and Docking Studies of Substituted Aryl Thiazolyl Phenylsulfonamides as Potential Protein Tyrosine Phosphatase 1B Inhibitors
Kanika Varshney et al.
CHEMMEDCHEM (2012)
Synthesis and evaluation of oxovanadium(IV) complexes of Schiff-base condensates from 5-substituted-2-hydroxybenzaldehyde and 2-substituted-benzenamine as selective inhibitors of protein tyrosine phosphatase 1B
Hong Han et al.
DALTON TRANSACTIONS (2012)
Design, synthesis, and evaluation of 2-substituted ethenesulfonic acid ester derivatives as protein tyrosine phosphatase 1B inhibitors
Jingbao Liu et al.
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (2012)
New 4-[(5-arylidene-2-arylimino-4-oxo-3-thiazolidinyl)methyl]benzoic acids active as protein tyrosine phosphatase inhibitors endowed with insulinomimetic effect on mouse C2C12 skeletal muscle cells
Rosaria Ottana et al.
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (2012)
Synthesis, in vitro and in silico screening of ethyl 2-(6-substituted benzo[d]thiazol-2-ylamino)-2-oxoacetates as protein-tyrosine phosphatase 1B inhibitors
Gabriel Navarrete-Vazquez et al.
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (2012)
Pyrroloquinoline quinone stimulates epithelial cell proliferation by activating epidermal growth factor receptor through redox cycling
Kazuki Kimura et al.
FREE RADICAL BIOLOGY AND MEDICINE (2012)
Antihyperglycemic effect of Annona squamosa hexane extract in type 2 diabetes animal model: PTP1B inhibition, a possible mechanism of action?
Joseph Alex Davis et al.
INDIAN JOURNAL OF PHARMACOLOGY (2012)
Rational Design of Selective Organoruthenium Inhibitors of Protein Tyrosine Phosphatase 1B
Jun Xiang Ong et al.
INORGANIC CHEMISTRY (2012)
Molecular Dynamics Approach to Probe the Allosteric Inhibition of PTP1B by Chlorogenic and Cichoric Acid
Sarath Kumar Baskaran et al.
JOURNAL OF CHEMICAL INFORMATION AND MODELING (2012)
A Highly Selective and Potent PTP-MEG2 Inhibitor with Therapeutic Potential for Type 2 Diabetes
Sheng Zhang et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2012)
Dysidavarones A-D, New Sesquiterpene Quinones from the Marine Sponge Dysidea avara
Wei-Hua Jiao et al.
ORGANIC LETTERS (2012)
Bioguided Isolation of (9Z)-Octadec-9-enoic Acid from Phellodendron amurense Rupr. and Identification of Fatty Acids as PTP1B Inhibitors
Dirk Steinmann et al.
PLANTA MEDICA (2012)
Protein Tyrosine Phosphatase 1B (PTP1B)-Inhibiting Constituents from the Leaves of Syzygium polyanthum
Azis Saifudin et al.
PLANTA MEDICA (2012)
Ratanhiaphenol III from Ratanhiae Radix is a PTP1B Inhibitor
Elke H. Heiss et al.
PLANTA MEDICA (2012)
(+)-Rutamarin as a Dual Inducer of Both GLUT4 Translocation and Expression Efficiently Ameliorates Glucose Homeostasis in Insulin-Resistant Mice
Yu Zhang et al.
PLOS ONE (2012)
High-resolution dose-response screening using droplet-based microfluidics
Oliver J. Miller et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2012)
The worldwide diabetes epidemic
David W. Lam et al.
CURRENT OPINION IN ENDOCRINOLOGY DIABETES AND OBESITY (2012)
Novel protein tyrosine phosphatase 1B inhibitors: interaction requirements for improved intracellular efficacy in type 2 diabetes mellitus and obesity control
Doina Popov
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2011)
Tea contains potent inhibitors of tyrosine phosphatase PTP1B
Junfeng Ma et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2011)
Potent inhibition of protein tyrosine phosphatases by copper complexes with multi-benzimidazole derivatives
Ying Li et al.
BIOMETALS (2011)
Facile fabrication of promising protein tyrosine phosphatase (PTP) inhibitor entities based on 'clicked' serine/threonine-monosaccharide hybrids
Xiao-Peng He et al.
BIOORGANIC & MEDICINAL CHEMISTRY (2011)
New 5-deoxyflavonoids and their inhibitory effects on protein tyrosine phosphatase 1B (PTP1B) activity
Phi Hung Nguyen et al.
BIOORGANIC & MEDICINAL CHEMISTRY (2011)
Pyrrolo[2,3-c]azepine derivatives: A new class of potent protein tyrosine phosphatase 1B inhibitors
Jianwei Xie et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2011)
A unique and rapid approach toward the efficient development of novel protein tyrosine phosphatase (PTP) inhibitors based on 'clicked' pseudo-glycopeptides
Jin-Wei Yang et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2011)
Design, synthesis, and evaluation of bromo-retrochalcone derivatives as protein tyrosine phosphatase 1B inhibitors
Zhiguo Liu et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2011)
Protein Tyrosine Phosphatase 1B and α-Glucosidase Inhibitory Phlorotannins from Edible Brown Algae, Ecklonia stolonifera and Eisenia bicyclis
Hye Eun Moon et al.
BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY (2011)
Preparation of triazole-linked glycosylated α-ketocarboxylic acid derivatives as new PTP1B inhibitors
Zhuo Song et al.
CARBOHYDRATE RESEARCH (2011)
Chemical Constituents from Sambucus adnata and Their Protein–Tyrosine Phosphatase 1B Inhibitory Activities
Tatsunori Sasaki et al.
CHEMICAL & PHARMACEUTICAL BULLETIN (2011)
2-Acyl-tetrahydroisoquinoline-3-carboxylic Acids: Lead Compounds with Triple Actions, Peroxisome Proliferator-Activated Receptor α/γ Agonist and Protein-Tyrosine Phosphatase 1B Inhibitory Activities
Kazuya Otake et al.
CHEMICAL & PHARMACEUTICAL BULLETIN (2011)
A Novel Series of (S)-2,7-Substituted-1,2,3,4-tetrahydroisoquinoline-3-carboxylic Acids: Peroxisome Proliferator-Activated Receptor α/γ Dual Agonists with Protein-Tyrosine Phosphatase 1B Inhibitory Activity
Kazuya Otake et al.
CHEMICAL & PHARMACEUTICAL BULLETIN (2011)
Synthesis of (Glycopyranosyl-triazolyl)-purines and Their Inhibitory Activities against Protein Tyrosine Phosphatase 1B (PTP1B)
Lei Luo et al.
CHEMISTRY & BIODIVERSITY (2011)
Isoxazol-5(4H) one Derivatives as PTP1B Inhibitors Showing an Anti-Obesity Effect
Bhooshan Kafle et al.
CHEMISTRY-AN ASIAN JOURNAL (2011)
Discovery of Orally Active, Potent, and Selective Benzotriazole-Based PTP1B Inhibitors
Dipam Patel et al.
CHEMMEDCHEM (2011)
Potent inhibition of protein tyrosine phosphatases by quinquedentate binuclear copper complexes: synthesis, characterization and biological activities
Qingming Wang et al.
DALTON TRANSACTIONS (2011)
Mononuclear copper(II) complexes with 3,5-substituted-4-salicylidene-amino-3,5-dimethyl-1,2,4-triazole: synthesis, structure and potent inhibition of protein tyrosine phosphatases
Ling Ma et al.
DALTON TRANSACTIONS (2011)
Synthesis and biological evaluation of (±)-3-(2-(2-fluorobenzyloxy) naphthalen-6-yl)-2-aminopropanoic acid derivatives as novel PTP1B inhibitors
Liang-Peng Sun et al.
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (2011)
Click to a focused library of benzyl 6-triazolo(hydroxy)benzoic glucosides: Novel construction of PTP1B inhibitors on a sugar scaffold
Cui Li et al.
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (2011)
Dinuclear copper complexes of organic claw: Potent inhibition of protein tyrosine phosphatases
Ling Ma et al.
JOURNAL OF INORGANIC BIOCHEMISTRY (2011)
Ternary oxovanadium(IV) complexes with amino acid-Schiff base and polypyridyl derivatives: Synthesis, characterization, and protein tyrosine phosphatase 1B inhibition
Liping Lu et al.
JOURNAL OF INORGANIC BIOCHEMISTRY (2011)
Hippolides A-H, Acyclic Manoalide Derivatives from the Marine Sponge Hippospongia lachne
Shu-Juan Piao et al.
JOURNAL OF NATURAL PRODUCTS (2011)
Structural and stereochemical studies of five new pregnane steroids from the stem bark of Toona ciliata var. pubescens
Jian-Rong Wang et al.
STEROIDS (2011)
Discovery of novel PTP1B inhibitors with antihyperglycemic activity
Zhang Liu et al.
ACTA PHARMACOLOGICA SINICA (2010)
Dammaranes from Gynostemma pentaphyllum and synthesis of their derivatives as inhibitors of protein tyrosine phosphatase 1B
Ji-Qing Xu et al.
BIOORGANIC & MEDICINAL CHEMISTRY (2010)
Design and synthesis of 2,4-disubstituted polyhydroquinolines as prospective antihyperglycemic and lipid modulating agents
Atul Kumar et al.
BIOORGANIC & MEDICINAL CHEMISTRY (2010)
Novel thiophene derivatives as PTP1B inhibitors with selectivity and cellular activity
Deju Ye et al.
BIOORGANIC & MEDICINAL CHEMISTRY (2010)
Design, synthesis and docking studies on phenoxy-3-piperazin-1-yl-propan-2-ol derivatives as protein tyrosine phosphatase 1B inhibitors
Swati Gupta et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2010)
Prenylflavonoids from Glycyrrhiza uralensis and their protein tyrosine phosphatase-1B inhibitory activities
Songpei Li et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2010)
Highly brominated metabolites from marine red alga Laurencia similis inhibit protein tyrosine phosphatase 1B
Jianchun Qin et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2010)
Novel thiazolidinedione derivatives with anti-obesity effects: Dual action as PTP1B inhibitors and PPAR-γ activators
Bharat Raj Bhattarai et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2010)
Inhibition of protein tyrosine phosphatase 1B and regulation of insulin signalling markers by caffeoyl derivatives of chicory (Cichorium intybus) salad leaves
V. S. Muthusamy et al.
BRITISH JOURNAL OF NUTRITION (2010)
Phytochemical mediated gold nanoparticles and their PTP 1B inhibitory activity
Sabjan Khaleel Basha et al.
COLLOIDS AND SURFACES B-BIOINTERFACES (2010)
Synthesis and evaluation of some novel dibenzo[b,d]furan carboxylic acids as potential anti-diabetic agents
N. Lakshminarayana et al.
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (2010)
Synthesis, characterization, and protein tyrosine phosphatases inhibition activities of oxovanadium(IV) complexes with Schiff base and polypyridyl derivatives
Caixia Yuan et al.
JOURNAL OF INORGANIC BIOCHEMISTRY (2010)
A Focused Library of Protein Tyrosine Phosphatase Inhibitors
Anthony B. Comeau et al.
JOURNAL OF MEDICINAL CHEMISTRY (2010)
Synthesis and Biological Evaluation of Oleanolic Acid Derivatives As Inhibitors of Protein Tyrosine Phosphatase 1B
Shan Qian et al.
JOURNAL OF NATURAL PRODUCTS (2010)
Bioactivity-Guided Isolation of 1,2,3,4,6-Penta-O-galloyl-D-glucopyranose from Paeonia lactiflora Roots As a PTP1B Inhibitor
Renate R. Baumgartner et al.
JOURNAL OF NATURAL PRODUCTS (2010)
Inhibition of PTP1B by Trodusquemine (MSI-1436) Causes Fat-specific Weight Loss in Diet-induced Obese Mice
Kristen A. Lantz et al.
OBESITY (2010)
Protein Tyrosine Phosphatase 1B Inhibitory Activity of 24-Norursane Triterpenes Isolated from Weigela subsessilis
MinKyun Na et al.
PHYTOTHERAPY RESEARCH (2010)
Psidials A-C, Three Unusual Meroterpenoids from the Leaves of Psidium guajava L
Hui-Zheng Fu et al.
ORGANIC LETTERS (2010)
New Prenylated Flavanones from Erythrina abyssinica with Protein Tyrosine Phosphatase 1B (PTP1B) Inhibitory Activity
Long Cui et al.
PLANTA MEDICA (2010)
Insulin signaling meets mitochondria in metabolism
Zhiyong Cheng et al.
TRENDS IN ENDOCRINOLOGY AND METABOLISM (2010)
Docking Simulations and in Vitro Assay Unveil Potent Inhibitory Action of Papaverine against Protein Tyrosine Phosphatase 1B
Yasser Bustanji et al.
BIOLOGICAL & PHARMACEUTICAL BULLETIN (2009)
Synthesis, in vitro and computational studies of protein tyrosine phosphatase 1B inhibition of a small library of 2-arylsulfonylaminobenzothiazoles with antihyperglycemic activity
Gabriel Navarrete-Vazquez et al.
BIOORGANIC & MEDICINAL CHEMISTRY (2009)
Synthesis, activity and molecular modeling of a new series of chromones as low molecular weight protein tyrosine phosphatase inhibitors
Marco Forghieri et al.
BIOORGANIC & MEDICINAL CHEMISTRY (2009)
5-Arylidene-2-phenylimino-4-thiazolidinones as PTP1B and LMW-PTP inhibitors
Rosaria Ottana et al.
BIOORGANIC & MEDICINAL CHEMISTRY (2009)
Protein tyrosine phosphatase 1B inhibitors isolated from Morus bombycis
Duc Manh Hoang et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2009)
Thiazolidinedione derivatives as PTP1B inhibitors with antihyperglycemic and antiobesity effects
Bharat Raj Bhattarai et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2009)
A novel sesquiterpene quinone from Hainan sponge Dysidea villosa
Yan Li et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2009)
Isolation of the protein tyrosine phosphatase 1B inhibitory metabolite from the marine-derived fungus Cosmospora sp SF-5060
Changon Seo et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2009)
Synthesis of protein tyrosine phosphatase 1B inhibitors: Model validation and docking studies
Anil K. Saxena et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2009)
Protein tyrosine phosphatase 1B inhibitory effects of depsidone and pseudodepsidone metabolites from the Antarctic lichen Stereocaulon alpinum
Changon Seo et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2009)
Inhibitory effect of chalcones and their derivatives from Glycyrrhiza inflata on protein tyrosine phosphatase 1B
Goo Yoon et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2009)
Synthesis and biological evaluation of heterocyclic ring-substituted maslinic acid derivatives as novel inhibitors of protein tyrosine phosphatase 1B
Wen-Wei Qiu et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2009)
Cytotoxic and PTP1B inhibitory activities from Erythrina abyssinica
Phi Hung Nguyen et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2009)
Structure-Based Optimization of Benzoic Acids as Inhibitors of Protein Tyrosine Phosphatase 1B and Low Molecular Weight Protein Tyrosine Phosphatase
Rosanna Maccari et al.
CHEMMEDCHEM (2009)
Novel 2-aryl-naphtho[1,2-d]oxazole derivatives as potential PTP-1B inhibitors showing antihyperglycemic activities
Atul Kumar et al.
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (2009)
Structure-based virtual screening approach to identify novel classes of PTP1B inhibitors
Hwangseo Park et al.
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (2009)
Gombapyrones, new α-pyrone metabolites produced by Streptomyces griseoruber Acta 3662
Soleiman Helaly et al.
JOURNAL OF ANTIBIOTICS (2009)
Piceamycin and its N-acetylcysteine adduct is produced by Streptomyces sp GB 4-2
Dirk Schulz et al.
JOURNAL OF ANTIBIOTICS (2009)
Ternary oxovanadium(IV) complexes of ONO-donor Schiff base and polypyridyl derivatives as protein tyrosine phosphatase inhibitors: synthesis, characterization, and biological activities
Caixia Yuan et al.
JOURNAL OF BIOLOGICAL INORGANIC CHEMISTRY (2009)
Inhibition of protein tyrosine phosphatase 1B by lupeol and lupenone isolated from Sorbus commixta
Minkyun Na et al.
JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY (2009)
PTP1B inhibitory effects of tridepside and related metabolites isolated from the Antarctic lichen Umbilicaria antarctica
Changon Seo et al.
JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY (2009)
Protein tyrosine phosphatase 1B inhibitory by dammaranes from Vietnamese Giao-Co-Lam tea
Tran Manh Hung et al.
JOURNAL OF ETHNOPHARMACOLOGY (2009)
Chemical Constituents from the Aerial Parts of Artemisia minor
Zhi-Zhou He et al.
JOURNAL OF NATURAL PRODUCTS (2009)
Chemical Constituents of the Roots of Euphorbia micractina
Wendong Xu et al.
JOURNAL OF NATURAL PRODUCTS (2009)
Isolation of Betulinic Acid, its Methyl Ester and Guaiane Sesquiterpenoids with Protein Tyrosine Phosphatase 1B Inhibitory Activity from the Roots of Saussurea lappa CBClarke
Ji Young Choi et al.
MOLECULES (2009)
Pterocarpans with inhibitory effects on protein tyrosine phosphatase 1B from Erythrina lysistemon Hutch.
Trong Tuan Dao et al.
PHYTOCHEMISTRY (2009)
Diastereoisomeric macrocyclic polydisulfides from the mangrove Bruguiera gymnorrhiza
Xiao-Ying Huang et al.
PHYTOCHEMISTRY (2009)
High-throughput synthesis of azide libraries suitable for direct click chemistry and in situ screening
Rajavel Srinivasan et al.
ORGANIC & BIOMOLECULAR CHEMISTRY (2009)
Discovery of a novel competitive inhibitor of PTP1B by high-throughput screening
Lei Shi et al.
ACTA PHARMACOLOGICA SINICA (2008)
Synthesis and anti-HBV activities evaluation of new ethyl 8-imidazolylmethyl-7-hydroxyquinoline-3-carboxylate derivatives in vitro
Yajing Liu et al.
ARCHIV DER PHARMAZIE (2008)
Oleanolic acid and its derivatives: New inhibitor of protein tyrosine phosphatase 1B with cellular activities
Yi-Nan Zhang et al.
BIOORGANIC & MEDICINAL CHEMISTRY (2008)
A re-examination of the difluoromethylenesulfonic acid group as a phosphotyrosine mimic for PTP1B inhibition
Munawar Hussain et al.
BIOORGANIC & MEDICINAL CHEMISTRY (2008)
Synthesis of triazole-linked β-C-glycosyl dimers as inhibitors of PTP1B
Li Lin et al.
BIOORGANIC & MEDICINAL CHEMISTRY (2008)
Ohioensins F and G:: Protein tyrosine phosphatase 1B inhibitory benzonaphthoxanthenones from the Antarctic moss Polytrichastrum alpinum
Changon Seo et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2008)
β-C-Glycosiduronic acids and β-C-glycosyl compounds: New PTP1B inhibitors
Li Lin et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2008)
Discovery of [(3-bromo-7-cyano-2-naphthyl)(difluoro)-methyl]phosphonic acid, a potent and orally active small molecule PTP1B inhibitor
Yongxin Han et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2008)
PTP1B inhibitors: Synthesis and evaluation of difluoro-methylenephosphonate bioisosteres on a sulfonamide scaffold
Christopher P. Holmes et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2008)
Isothiazolidinone inhibitors of PTP1B containing imidazoles and imidazolines
Brent Douty et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2008)
Targeting PTPs with small molecule inhibitors in cancer treatment
Zhong-Xing Jiang et al.
CANCER AND METASTASIS REVIEWS (2008)
Prenylated flavonoids with PTP1B inhibitory activity from the root bark of Erythrina mildbraedii
JunPil Jang et al.
CHEMICAL & PHARMACEUTICAL BULLETIN (2008)
Tannins present in Cichorium intybus enhance glucose uptake and inhibit adipogenesis in 3T3-L1 adipocytes through PTP1B inhibition
V. S. Muthusamy et al.
CHEMICO-BIOLOGICAL INTERACTIONS (2008)
Structure-Based Optimization of Protein Tyrosine Phosphatase-1 B Inhibitors: Capturing Interactions with Arginine 24
Zhao-Kui Wan et al.
CHEMMEDCHEM (2008)
Synthesis, anti-bacterial, anti-asthmatic and anti-diabetic activities of novel N-substituted-2-(4-phenylethynyl-phenyl)-1H-benzimidazoles and N-substituted 2[4-(4,4-dimethyl-thiochroman-6-yl-ethynyl)-phenyl)-1H-benzimidazoles
Ramanatham Vinodkumar et al.
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (2008)
Molecular dynamics simulation study of PTP1B with allosteric inhibitor and its application in receptor based pharmacophore modeling
Kavitha Bharatham et al.
JOURNAL OF COMPUTER-AIDED MOLECULAR DESIGN (2008)
Identification of pongamol and karanjin as lead compounds with anti hyperglycemic activity from Pongamia pinnata fruits
Akhilesh K. Tamrakar et al.
JOURNAL OF ETHNOPHARMACOLOGY (2008)
Inhibition of protein tyrosine phosphatase 1B and alkaline phosphatase by bis(maltolato)oxovanadium (IV)
Ming Li et al.
JOURNAL OF INORGANIC BIOCHEMISTRY (2008)
Sesquiterpenes from the Hainan sponge Dysidea septosa
Xiao-Chun Huang et al.
JOURNAL OF NATURAL PRODUCTS (2008)
Triterpenoids from the Leaves of Diospyros kaki (Persimmon) and Their Inhibitory Effects on Protein Tyrosine Phosphatase 1B
Phuong Thien Thuong et al.
JOURNAL OF NATURAL PRODUCTS (2008)
Usimines A-C, bioactive usnic acid derivatives from the Antarctic lichen Stereocaulon alpinum
Changon Seo et al.
JOURNAL OF NATURAL PRODUCTS (2008)
Lipidyl Pseudopteranes A-F: Isolation, Biomimetic Synthesis, and PTP1B Inhibitory Activity of a New Class of Pseudopteranoids from the Gorgonian Pseudopterogorgia acerosa
Abhijeet S. Kate et al.
JOURNAL OF NATURAL PRODUCTS (2008)
Targeting Inactive Enzyme Conformation: Aryl Diketoacid Derivatives as a New Class of PTP1B Inhibitors
Sijiu Liu et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2008)
Synthesis, Molecular Docking and PTP1B Inhibitory Activity of Functionalized 4,5-Dihydronaphthofurans and Dibenzofurans
Atul Goel et al.
Medicinal Chemistry (2008)
Triterpenoids and a Sterol from the Stem-bark of Styrax japonica and Their Protein Tyrosine Phosphatase 1B Inhibitory Activities
Joo-Hee Kwon et al.
PHYTOTHERAPY RESEARCH (2008)
Solid-phase assembly and in situ screening of protein tyrosine phosphatase inhibitors
Rajavel Srinivasan et al.
ORGANIC LETTERS (2008)
2-Aryl-3,3,3-trifluoro-2-hydroxypropionic acids: A new class of protein tyrosine phosphatase 1B inhibitors
David R. Adams et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2007)
Vanillic acid derivatives from the green algae Cladophora socialis as potent protein tyrosine phosphatase 1B inhibitors
Yunjiang Feng et al.
JOURNAL OF NATURAL PRODUCTS (2007)
Mono- and disalicylic acid derivatives: PTP1B inhibitors as potential anti-obesity drugs
Sup Shrestha et al.
BIOORGANIC & MEDICINAL CHEMISTRY (2007)
Structure-based optimization of protein tyrosine phosphatase 1B inhibitors: From the active site to the second phosphotyrosine binding site
Douglas P. Wilson et al.
JOURNAL OF MEDICINAL CHEMISTRY (2007)
Kinetics and mechanism of protein tyrosine phosphatase 1B inactivation by acrolein
Derrick R. Seiner et al.
CHEMICAL RESEARCH IN TOXICOLOGY (2007)
Design, synthesis, and discovery of stilbene derivatives based on lithospermic acid B as potent protein tyrosine phosphatase 1B inhibitors
Mankil Jung et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2007)
Inhibitory effect of 2-arylbenzofurans from Erythrina addisoniae on protein tyrosine phosphatase-1B
MinKyun Na et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2007)
CoMFA based de novo design of pyridazine analogs as PTP1B inhibitors
Pramod C. Nair et al.
JOURNAL OF MOLECULAR GRAPHICS & MODELLING (2007)
Erythrina studies, part 51.: Isoprenylated flavonoids from the stem bark of Erythrina abyssinica
Long Cui et al.
JOURNAL OF NATURAL PRODUCTS (2007)
Probing acid replacements of thiophene PTP1B inhibitors
Zhao-Kui Wan et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2007)
Methylenedisalicylic acid derivatives: New PTP1B inhibitors that confer resistance to diet-induced obesity
Suja Shrestha et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2007)
PTP1B as a drug target: recent developments in PTP1B inhibitor discovery
Sheng Zhang et al.
DRUG DISCOVERY TODAY (2007)
Discovery of new potent human protein tyrosine phosphatase inhibitors via pharmacophore and QSAR analysis followed by in silico screening
Mutasem O. Taha et al.
JOURNAL OF MOLECULAR GRAPHICS & MODELLING (2007)
Structures, biogenesis, and biological activities of pyrano[4,3-c]isochromen-4-one derivatives from the fungus Phellinus igniarius
Ying Wang et al.
JOURNAL OF NATURAL PRODUCTS (2007)
Benzothiazole benzimidazole (S)-isothiazolidinone derivatives as protein tyrosine phosphatase-1B inhibitors
Richard B. Sparks et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2007)
Protein tyrosine phosphatase 1B inhibitory activity of amentoflavone and its cellular effect on tyrosine phosphorylation of insulin receptors
MinKyun Na et al.
BIOLOGICAL & PHARMACEUTICAL BULLETIN (2007)
Cellular inhibition of protein tyrosine phosphatase 1B by uncharged thioxothiazolidinone derivatives
Matthew Stuible et al.
CHEMBIOCHEM (2007)
Hyrtiosal, a PTP1B inhibitor from the marine sponge Hyrtios erectus, shows extensive cellular effects on PI3K/AKT activation, glucose transport, and TGFβ/Smad2 signaling
Tao Sun et al.
CHEMBIOCHEM (2007)
Synthesis of benzofuran scaffold-based potential PTP-1B inhibitors
Manish Dixit et al.
BIOORGANIC & MEDICINAL CHEMISTRY (2007)
Benzoquinones from Ardisia japonica with inhibitory activity towards human protein tyrosine phosphatase 1B (PTP1B)
Yan-Fang Li et al.
CHEMISTRY & BIODIVERSITY (2007)
Structural insights into the design of nonpeptidic isothiazolidinone-containing inhibitors of protein-tyrosine phosphatase 1B
Paul J. Ala et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2006)
Protein tyrosine phosphatase-1B inhibitory activity of isoprenylated flavonoids isolated from Erythrina mildbraedii
MinKyun Na et al.
JOURNAL OF NATURAL PRODUCTS (2006)
Structural basis for inhibition of protein-tyrosine phosphatase 1B by isothiazolidinone heterocyclic phosphonate mimetics
Paul J. Ala et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2006)
Monocyclic thiophenes as protein tyrosine phosphatase 1B inhibitors: Capturing interactions with Asp48
Zhao-Kui Wan et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2006)
Isothiazolidinone heterocycles as inhibitors of protein tyrosine phosphatases: Synthesis and structure-activity relationships of a peptide scaffold
Eddy W. Yue et al.
BIOORGANIC & MEDICINAL CHEMISTRY (2006)
Inhibition of protein tyrosine phosphatase 1B by lignans from Myristica fragrans
Senugmi Yang et al.
PHYTOTHERAPY RESEARCH (2006)
Inhibition of protein tyrosine phosphatase 1B by prenylated isoflavonoids isolated from the stem bark of Erythrina addisoniae
Eun Young Bae et al.
PLANTA MEDICA (2006)
PTP1B inhibitory activity of kaurane diterpenes isolated from Siegesbeckia glabrescens
Sohee Kim et al.
JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY (2006)
Potent benzimidazole sulfonamide protein tyrosine phosphatase 1B inhibitors containing the Heterocyclic (S)-isothiazolidinone phosphotyrosine mimetic
Andrew P. Combs et al.
JOURNAL OF MEDICINAL CHEMISTRY (2006)
Protein tyrosine phosphatase 1B inhibitory activity of triterpenes isolated from Astilbe koreana
MinKyun Na et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2006)
Inhibition of protein tyrosine phosphatase 1B by diterpenoids isolated from Acanthopanax koreanum
MK Na et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2006)
Synthesis of novel benzofuran isoxazolines as protein tyrosine phosphatase 1B inhibitors
G Ahmad et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2006)
O-methyl nakafuran-8 lactone, a new sesquiterpenoid from a hainan marine sponge Dysidea sp.
Z. -Y. Shao et al.
JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH (2006)
Bicyclic and tricyclic thiophenes as protein tyrosine phosphatase 1B inhibitors
AF Moretto et al.
BIOORGANIC & MEDICINAL CHEMISTRY (2006)
PTP1-B inhibitors from Saussrurea Lappa
S. Li et al.
JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH (2006)
Berberine potently inhibits protein tyrosine phosphatase 1B: Investigation by docking simulation and experimental validation
Yasser Bustanji et al.
JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY (2006)
Conformation-assisted inhibition of protein-tyrosine phosphatase-1B elicits inhibitor selectivity over T-cell protein-tyrosine phosphatase
E Asante-Appiah et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2006)
1,2,3,4-tetrahydroisoquinolinyl sulfamic acids as phosphatase PTP1B inhibitors
SR Klopfenstein et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2006)
Protein tyrosine phosphatase 1B inhibitors from Morus root bark
L Cui et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2006)
Residues distant from the active site influence protein-tyrosine phosphatase 1B inhibitor binding
J Montalibet et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2006)
Rapid assembly and in situ screening of bidentate inhibitors of protein tyrosine phosphatases
R Srinivasan et al.
ORGANIC LETTERS (2006)
Inhibition of protein tyrosine phosphatase 1B by ursane-type triterpenes isolated from Symplocos paniculata
M Na et al.
PLANTA MEDICA (2006)
PTP-1B inhibitors:: Cyclopenta[d][1,2]-oxazine derivatives
SY Cho et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2006)
Discovery and structure-activity relationships of novel sulfonamides as potent PTP1B inhibitors
CP Holmes et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2005)
Synthesis of tripeptides as potent Yersinia protein tyrosine phosphatase inhibitors
K Lee et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2005)
PTP1B inhibitory effect of abietane diterpenes isolated from Salvia miltiorrhiza
YM Han et al.
BIOLOGICAL & PHARMACEUTICAL BULLETIN (2005)
Synthesis of functionalized acetophenones as protein tyrosine phosphatase 1B inhibitors
M Dixit et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2005)
Allosteric inhibition of PTP1B activity by selective modification of a non-active site cysteine residue
SK Hansen et al.
BIOCHEMISTRY (2005)
Allele-specific inhibitors of protein tyrosine phosphatases
HE Hoffman et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2005)
Formylchromone derivatives as irreversible and selective inhibitors of human protein tyrosine phosphatase 1B. Kinetic and modeling studies
YS Shim et al.
BIOORGANIC & MEDICINAL CHEMISTRY (2005)
Development of an automated protein-tyrosine phosphatase 1B inhibition assay and the screening of putative insulin-enhancing vanadium(IV) and zinc(II) complexes
AP Seale et al.
BIOTECHNOLOGY LETTERS (2005)
PTP1B inhibitors from Ardisia japonica
YF Li et al.
JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH (2005)
Fragment-based lead discovery using X-ray crystallography
MJ Hartshorn et al.
JOURNAL OF MEDICINAL CHEMISTRY (2005)
Small molecule approach to studying protein tyrosine phosphatase
S Kumar et al.
METHODS (2005)
In vitro protein tyrosine phosphatase 1B inhibitory phenols from the seeds of Psoralea corylifolia
YC Kim et al.
PLANTA MEDICA (2005)
Suramin derivatives as inhibitors and activators of protein-tyrosine phosphatases
DF McCain et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
The development of potent non-peptidic PTP-1B inhibitors
C Dufresne et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2004)
Structure based design of a series of potent and selective non peptidic PTP-1B inhibitors
CK Lau et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2004)
Discovery of a novel protein tyrosine phosphatase-1B inhibitor, KR61639: potential development as an antihyperglycemic agent
HG Cheon et al.
EUROPEAN JOURNAL OF PHARMACOLOGY (2004)
Discovery of novel PTP1b inhibitors
DA Ockey et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2004)
α,α-difluoro-β-ketophosphonates as potent inhibitors of protein tyrosine phosphatase 1B
XF Li et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2004)
Allosteric inhibition of protein tyrosine phosphatase 1B
C Wiesmann et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2004)
Inhibition of PTP1B by metabolites from Micromucor ramannianus var. angulisporus CRM000232
H Oh et al.
JOURNAL OF ANTIBIOTICS (2004)
Isoxazole carboxylic acids as protein tyrosine phosphatase 1B (PTP1B) inhibitors
HY Zhao et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2004)
The core structures of roseophilin and the prodigiosin alkaloids define a new class of protein tyrosine phosphatase inhibitors
A Fürstner et al.
CHEMBIOCHEM (2004)
Structure-based design of selective and potent inhibitors of protein-tyrosine phosphatase β
IK Lund et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
Identification of a monoacid-based, cell permeable, selective inhibitor of protein tyrosine phosphatase 1B
ZL Xin et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2003)
Cellular effects of small molecule PTP1B inhibitors on insulin signaling
LP Xie et al.
BIOCHEMISTRY (2003)
The structural basis for the selectivity of benzotriazole inhibitors of PTP1B
G Scapin et al.
BIOCHEMISTRY (2003)
Discovery and SAR of novel, potent and selective protein tyrosine phosphatase 1B inhibitors
ZH Pei et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2003)
Fragment screening and assembly: A highly efficient approach to a selective and cell active protein tyrosine phosphatase 1B inhibitor
G Liu et al.
JOURNAL OF MEDICINAL CHEMISTRY (2003)
Acylsulfonamide-containing PTP1B inhibitors designed to mimic an enzyme-bound water of hydration
DG Liu et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2003)
Formylchromone derivatives as a novel class of protein tyrosine phosphatase 1B inhibitors
YS Shim et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2003)
Selective protein tyrosine phosphatase 1B inhibitors: Targeting the second phosphotyrosine binding site with non-carboxylic acid-containing ligands
G Liu et al.
JOURNAL OF MEDICINAL CHEMISTRY (2003)
Molecular design and biological activities of protein-tyrosine phosphatase inhibitors
K Umezawa et al.
PHARMACOLOGY & THERAPEUTICS (2003)
Discovery and structure-activity relationship of oxalylarylaminobenzoic acids as inhibitors of protein tyrosine phosphatase 1B
G Liu et al.
JOURNAL OF MEDICINAL CHEMISTRY (2003)
Discovery of a potent, selective protein tyrosine phosphatase 1B inhibitor using a linked-fragment strategy
BG Szczepankiewicz et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2003)
Modification of the N-terminus of peptidomimetic protein tyrosine phosphatase 1B (PTP1B) inhibitors: Identification of analogues with cellular activity
SD Larsen et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2003)
An overview of the protein tyrosine phosphatase superfamily
WQ Wang et al.
CURRENT TOPICS IN MEDICINAL CHEMISTRY (2003)
Natural PTP1B inhibitors from Broussonetia papyrifera
RM Chen et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2002)
Synthesis of [difluoro-(3-alkenylphenyl)-methyl]-phosphonic acids on non-crosslinked polystyrene and their evaluation as inhibitors of PTP1B
G Hum et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2002)
Probing the molecular basis for potent and selective protein-tyrosine phosphatase 1B inhibition
XL Guo et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
Discovery and SAR of a novel selective and orally bioavailable nonpeptide classical competitive inhibitor class of protein-tyrosine phosphatase 1B
HS Andersen et al.
JOURNAL OF MEDICINAL CHEMISTRY (2002)
Protein tyrosine phosphatase 1B inhibitors for diabetes
TO Johnson et al.
NATURE REVIEWS DRUG DISCOVERY (2002)
Divalent and trivalent α-ketocarboxylic acids as inhibitors of protein tyrosine phosphatases
YT Chen et al.
JOURNAL OF MEDICINAL CHEMISTRY (2002)
Peptidyl aldehydes as reversible covalent inhibitors of protein tyrosine phosphatases
H Fu et al.
BIOCHEMISTRY (2002)
Synthesis and PTP1B inhibition of 1,2-naphthoquinone derivatives as potent anti-diabetic agents
JH Ahn et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2002)
Structural basis for inhibition of protein tyrosine phosphatases by Keggin compounds phosphomolybdate and phosphotungstate
YS Heo et al.
EXPERIMENTAL AND MOLECULAR MEDICINE (2002)
The difluoromethylenesulfonic acid group as a monoanionic phosphate surrogate for obtaining PTP1B inhibitors
C Leung et al.
BIOORGANIC & MEDICINAL CHEMISTRY (2002)
Molecular docking and high-throughput screening for novel inhibitors of protein tyrosine phosphatase-1B
TN Doman et al.
JOURNAL OF MEDICINAL CHEMISTRY (2002)
Investigation of potential bioisosteric replacements for the carboxyl groups of peptidomimetic inhibitors of protein tyrosine phosphatase 1B: Identification of a tetrazole-containing inhibitor with cellular activity
C Liljebris et al.
JOURNAL OF MEDICINAL CHEMISTRY (2002)
Synthesis and biological activity of a novel class of small molecular weight peptidomimetic competitive inhibitors of protein tyrosine phosphatase 1B
SD Larsen et al.
JOURNAL OF MEDICINAL CHEMISTRY (2002)
Structure of protein tyrosine phosphatase 1B in complex with inhibitors bearing two phosphotyrosine mimetics
ZC Jia et al.
JOURNAL OF MEDICINAL CHEMISTRY (2001)
Acquisition of a specific and potent PTP1B inhibitor from a novel combinatorial library and screening procedure
K Shen et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
Molecular basis for the dephosphorylation of the activation segment of the insulin receptor by protein tyrosine phosphatase 1B
A Salmeen et al.
MOLECULAR CELL (2000)
Synthesis and PTP1B inhibition of novel 4-aryl-1-oxa-9-thiacyclopenta[b]fluorenes
J Wrobel et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2000)
Hydroxamido vanadates: aqueous chemistry and function in protein tyrosine phosphatases and cell cultures
AS Tracey
JOURNAL OF INORGANIC BIOCHEMISTRY (2000)
Structure-based design of a low molecular weight, nonphosphorus, nonpeptide, and highly selective inhibitor of protein-tyrosine phosphatase 1B
LF Iversen et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2000)
Novel benzofuran and benzothiophene biphenyls as inhibitors of protein tyrosine phosphatase 1B with antihyperglycemic properties
MS Malamas et al.
JOURNAL OF MEDICINAL CHEMISTRY (2000)
New azolidinediones as inhibitors of protein tyrosine phosphatase 1B with antihyperglycemic properties
MS Malamas et al.
JOURNAL OF MEDICINAL CHEMISTRY (2000)
Examination of novel non-phosphorus-containing phosphotyrosyl mimetics against protein-tyrosine phosphatase-1B and demonstration of differential affinities toward Grb2 SH2 domains
Y Gao et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2000)
Inhibition of protein tyrosine phosphatases by low-molecular-weight S-nitrosothiols and S-nitrosylated human serum albumin
M Xian et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2000)
Structure-based discovery of small molecule inhibitors targeted to protein tyrosine phosphatase 1B
M Sarmiento et al.
JOURNAL OF MEDICINAL CHEMISTRY (2000)
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