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The regulatory role of autophagy-related miRNAs in lung cancer drug resistance

BIOMEDICINE & PHARMACOTHERAPY (2022)

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miR-133a targets YES1 to reduce cisplatin resistance in ovarian cancer by regulating cell autophagy

Yang Zhou et al.

Summary: The study found that miR-133a expression was decreased in cisplatin-resistant ovarian cancer cells, and overexpression of miR-133a reduced cisplatin resistance. MiR-133a binds to the 3'UTR of YES1 and downregulates its expression. YES1 expression was upregulated in cisplatin-resistant ovarian cancer tissue, and miR-133a downregulated YES1 to inhibit cell autophagy and reduce cisplatin resistance.

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MicroRNA-20a-5p inhibits the autophagy and cisplatin resistance in ovarian cancer via regulating DNMT3B-mediated DNA methylation of RBP1

Hui Li et al.

Summary: In this study, researchers investigated the role of miR-20a-5p in modulating autophagy and cisplatin resistance in ovarian cancer. They found that miR-20a-5p suppresses malignant phenotypes and autophagy in cisplatin-resistant ovarian cancer cells. Furthermore, they demonstrated that DNMT3B mediates DNA methylation of RBP1, impairing its promoting effects on carcinogenesis and autophagy in ovarian cancer. Overall, the study highlights the importance of miR-20a-5p in the regulation of autophagy and cisplatin resistance in ovarian cancer.

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A Promising Treatment Strategy for Lung Cancer: A Combination of Radiotherapy and Immunotherapy

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Summary: Lung cancer is a leading cause of cancer-related deaths worldwide. Radiotherapy has achieved significant technical advances and is widely used in the management of lung cancer. The anti-tumor effect of radiotherapy is mainly caused by DNA damage in cancer cells. Additionally, radiotherapy induces anti-tumor immune responses, but also suppresses the immune system. Combining radiotherapy with immunotherapy, particularly immune checkpoint inhibitors, shows promise in overcoming immunosuppressive conditions in lung cancer patients. Particle therapy using protons and carbon ions in combination with immunotherapy is also a promising treatment strategy according to evidence outlined in this review.

CANCERS (2022)

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Article Oncology

Long noncoding RNA DANCR confers cytarabine resistance in acute myeloid leukemia by activating autophagy via the miR-874-3P/ATG16L1 axis

Hao Zhang et al.

Summary: This study identifies DANCR as a positive regulator of Ara-C resistance in human AML cells, suggesting that this lncRNA may serve as a potential target for overcoming Ara-C resistance in AML chemotherapy by promoting MIR-874-3P/ATG16L1 axis-regulated autophagy.

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The role of long non-codingRNAsin drug resistance of cancer

He-da Zhang et al.

Summary: Long non-coding RNAs (lncRNAs) are critical genomic regulators involved in genomic imprinting regulation, histone modification, gene expression regulation, and tumor initiation and progression. They are also associated with drug resistance in various types of cancer.

CLINICAL GENETICS (2021)

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Acetyl-11-keto-β-boswellic acid enhances the cisplatin sensitivity of non-small cell lung cancer cells through cell cycle arrest, apoptosis induction, and autophagy suppression via p21-dependent signaling pathway

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Summary: The combination treatment of AKBA and cisplatin enhances the sensitivity of NSCLC cells to cisplatin by regulating cell cycle, inducing apoptosis, and suppressing autophagy.

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Nuclear miR-30b-5p suppresses TFEB-mediated lysosomal biogenesis and autophagy

Huijie Guo et al.

Summary: The study revealed that miR-30b-5p can inhibit TFEB-dependent gene transcription by binding to CLEAR elements in the nucleus, thus affecting lysosomal biogenesis and autophagy. Knocking out miR-30b-5p increases TFEB transactivation, leading to increased expression of autophagy and lysosomal biogenesis-related genes.

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Restoration of miR-330 expression suppresses lung cancer cell viability, proliferation, and migration

Ali Mohammadi et al.

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JOURNAL OF CELLULAR PHYSIOLOGY (2021)

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Mechanisms of drug resistance mediated by long non-coding RNAs in non-small-cell lung cancer

Manuela La Montagna et al.

Summary: Non-small-cell lung cancer (NSCLC) is the most prevalent form of lung cancer with a poor five-year survival rate of 15%. While chemotherapy and targeted therapies have improved patient prognosis, some patients still relapse due to drug resistance. Recent research has focused on long non-coding RNAs (lncRNAs) and their role in regulating tumor growth and drug response mechanisms in NSCLC.

CANCER GENE THERAPY (2021)

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Esomeprazole overcomes paclitaxel-resistance and enhances anticancer effects of paclitaxel by inducing autophagy in A549/Taxol cells

Zhaoshi Bai et al.

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CELL BIOLOGY INTERNATIONAL (2021)

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MicroRNA-130b functions as an oncogene and is a predictive marker of poor prognosis in lung adenocarcinoma

Yeseul Kim et al.

Summary: This study found that high expression of miR-130b in lung adenocarcinoma is closely associated with poor prognosis, promoting tumor cell migration and invasion, and serving as a biomarker of unfavorable prognosis for patients. Targeting miR-130b may serve as a potential therapeutic strategy for lung cancer.

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Soudeh Ghafouri-Fard et al.

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miR-152/TNS1 axis inhibits non-small cell lung cancer progression through Akt/mTOR/RhoA pathway

Jinjin Duan et al.

Summary: The study found that TNS1 is upregulated in NSCLC cells and tissues, and is associated with the prognosis of NSCLC patients. Additionally, TNS1 promotes the growth and metastasis of NSCLC cells via the Akt/mTOR/RhoA pathway. miR-152 targets TNS1 to influence the progression of NSCLC.

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被撤回的出版物: miR-202-3p negatively regulates MMP-1 to inhibit the proliferation, migration and invasion of lung adenocarcinoma cells (Retracted article. See JAN, 2023)

Yong Li et al.

Summary: The study demonstrated the regulation of MMP-1 on proliferation, migration, and invasion of LUAD cells under the control of miR-202-3p, suggesting potential for new therapeutic strategies.

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Epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors for the treatment of non-small cell lung cancer: a patent review (2014-present)

Xin Sun et al.

Summary: EGFR, as a receptor for EGF, is closely related to the inhibition of tumor cell proliferation, invasion, and apoptosis, making it an important anti-tumor target. Small molecule inhibitors targeting EGFR have become crucial biologically active compounds for cancer treatment, especially against NSCLC. Despite significant progress in developing selective EGFR inhibitors, there is still an urgent need for new EGFR inhibitors that are safe, efficient, selective, and low-toxic to avoid adverse pharmacokinetics associated with wild-type EGFR.

EXPERT OPINION ON THERAPEUTIC PATENTS (2021)

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The Dual Role of Autophagy in Cancer Development and a Therapeutic Strategy for Cancer by Targeting Autophagy

Chul Won Yun et al.

Summary: Autophagy is a cellular degradation process that plays a role in regulating tumorigenesis, metastasis, cancer stem cells, and resistance to anticancer agents. While modulating autophagy may be a promising approach in anticancer therapy, its dual roles present limitations in its application.

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MicroRNA-3473b regulates the expression of TREM2/ULK1 and inhibits autophagy in inflammatory pathogenesis of Parkinson disease

Qiankun Lv et al.

Summary: Parkinson's disease is a neurodegenerative disorder characterized by selective loss of dopaminergic neurons. The microRNA miR-3473b has been shown to regulate autophagy and inflammatory factor secretion in PD, indicating a potential therapeutic target for modulating inflammation in Parkinson's disease.

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miR-139-5p enhances cisplatin sensitivity in non-small cell lung cancer cells by inhibiting cell proliferation and promoting apoptosis via the targeting of Homeobox protein Hox-B2

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Shuxian Dong et al.

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NATURE (2021)

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MicroRNA-142-3p inhibits autophagy and promotes intracellular survival of Mycobacterium tuberculosis by targeting ATG16L1 and ATG4c

Yuliang Qu et al.

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Kunmei Liu et al.

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FRONTIERS IN IMMUNOLOGY (2021)

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Review Biochemistry & Molecular Biology

The Role of mTOR Signaling as a Therapeutic Target in Cancer

Nadezhda V. Popova et al.

Summary: This review summarizes the current information on the role of phosphatidylinositol-3-kinase (PI3K)/AKT/mammalian target of rapamycin (mTOR) signaling in cancer as a potential target for new therapy options. The mTOR and PI3K/AKT/mTORC1 (mTOR complex 1) signaling pathways are critical for regulating fundamental cell processes, and their deregulation is implicated in cancer, metabolic dysregulation, and aging. The review also discusses recent data on the structure and function of the mTOR pathway, mechanisms of deregulation in human cancers, and the use of PI3K/AKT/mTOR inhibitors in clinical studies for cancer treatment, including issues of resistance and adverse effects.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2021)

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Targeted deletion of Atg5 in intestinal epithelial cells promotes dextran sodium sulfate-induced colitis

Kyohei Nishino et al.

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FDA Approval Summary: Atezolizumab and Durvalumab in Combination with Platinum-Based Chemotherapy in Extensive Stage Small Cell Lung Cancer

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miR-4486 reverses cisplatin-resistance of colon cancer cells via targeting ATG7 to inhibiting autophagy

Weiwei Wang et al.

Summary: The study revealed that in colon cancer cells resistant to cisplatin, miR-4486 expression was significantly reduced, and the overexpression of miR-4486 could increase sensitivity to cisplatin by inhibiting autophagy in HCT116/DDP and SW480/DDP cells. Additionally, ATG7 was identified as a target gene of miR-4486, indicating its role in reversing drug resistance.

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miR-582-5p Is a Tumor Suppressor microRNA Targeting the Hippo-YAP/TAZ Signaling Pathway in Non-Small Cell Lung Cancer

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Tumor Suppressor miR-584-5p Inhibits Migration and Invasion in Smoking Related Non-Small Cell Lung Cancer Cells by Targeting YKT6

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CANCERS (2021)

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The Local Anesthetic Bupivacaine Inhibits the Progression of Non-Small Cell Lung Cancer by Inducing Autophagy Through Akt/mTOR Signaling

Jian-Hua Gu et al.

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FRONTIERS IN ONCOLOGY (2021)

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Review Cell Biology

MicroRNAs in the regulation of autophagy and their possible use in age-related macular degeneration therapy

Juha M. T. Hyttinen et al.

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miR-30b-5p inhibits cancer progression and enhances cisplatin sensitivity in lung cancer through targeting LRP8

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CUL3 (cullin 3)-mediated ubiquitination and degradation of BECN1 (beclin 1) inhibit autophagy and promote tumor progression

Xuan Li et al.

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LncRNA MITA1 promotes ge fi tinib resistance by inducing autophagy in lung cancer cells

Jie Hu et al.

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BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER (2021)

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microRNA-320b suppresses HNF4G and IGF2BP2 expression to inhibit angiogenesis and tumor growth of lung cancer

Yu-Shui Ma et al.

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mTOR modulates resistance to gemcitabine in lung cancer in an MTORC2 dependent mechanism

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CELLULAR SIGNALLING (2021)

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Review Immunology

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IMMUNOLOGY LETTERS (2021)

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PI3K/Akt/mTOR signaling orchestrates the phenotypic transition and chemo-resistance of small cell lung cancer

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LncRNA-HOTAIR activates autophagy and promotes the imatinib resistance of gastrointestinal stromal tumor cells through a mechanism involving the miR-130a/ATG2B pathway

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miR-574-5p mediates epithelial-mesenchymal transition in small cell lung cancer by targeting vimentin via a competitive endogenous RNA network

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ONCOLOGY LETTERS (2021)

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ONCOLOGY LETTERS (2021)

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Circulating miR-320a Acts as a Tumor Suppressor and Prognostic Factor in Non-small Cell Lung Cancer

Akanksha Khandelwal et al.

Summary: The study found that circulating miR-320a levels were significantly down-regulated in patients with non-small cell lung cancer (NSCLC) and were associated with clinical characteristics such as tumor size, TNM stage, and lymph node metastasis. MiR-320a has a tumor-suppressive role in lung cancer by inhibiting tumor growth and metastasis, with AKT3 signaling pathways being activated in NSCLC due to down-regulated miR-320a levels.

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MiR-326 mediates malignant biological behaviors of lung adenocarcinoma by targeting ZEB1

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Pancreatic Cancer Signaling Pathways, Genetic Alterations, and Tumor Microenvironment: The Barriers Affecting the Method of Treatment

Darya Javadrashid et al.

Summary: Genetic alterations, particularly the K-Ras mutation, play a major role in the progression of pancreatic precursor lesions into PDAC. The tumor microenvironment and immune evasion are challenges in therapeutic approaches, with targeting signaling molecules and immune checkpoint inhibition showing promising results in pancreatic cancer treatment.

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miR-30a-5p suppresses lung squamous cell carcinoma via ATG5 - mediated autophagy

Jichen Yang et al.

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Autophagy receptor CCDC50 tunes the STING-mediated interferon response in viral infections and autoimmune diseases

Panpan Hou et al.

Summary: CCDC50, a newly identified autophagy receptor, plays a critical role in regulating STING-directed type I IFN signaling and immune response. Deficiency in CCDC50 may lead to overactivation of immune responses in SLE patients and enhanced immune response in HSV-1 infections.

CELLULAR & MOLECULAR IMMUNOLOGY (2021)

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Autophagy in major human diseases

Daniel J. Klionsky et al.

Summary: Autophagy is crucial for maintaining cellular and organismal homeostasis, and dysfunction in autophagy is implicated in the pathogenesis of major human disorders across various organ systems.

EMBO JOURNAL (2021)

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Article Biochemistry & Molecular Biology

miR-1 Targeted Downregulation of Bcl-2 Increases Chemosensitivity of Lung Cancer Cells

Cuimei Chen et al.

Summary: Bcl-2 is upregulated in lung cancer cells, negatively correlated with patient prognosis, while miR-1 affects the chemosensitivity of lung cancer cells by targeting Bcl-2.

GENETIC TESTING AND MOLECULAR BIOMARKERS (2021)

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miR-30a-5p mitigates autophagy by regulating the Beclin-1/ATG16 pathway in renal ischemia/reperfusion injury

Ye Fang et al.

Summary: The study demonstrated that miR-30a-5p expression levels were significantly decreased in renal I/R injury, suggesting a potential role in mitigating autophagy by regulating the Beclin-1/ATG16 pathway.

INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE (2021)

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MiR-133a-3p attenuates resistance of non-small cell lung cancer cells to gefitinib by targeting SPAG5

Qing Li et al.

Summary: The study revealed that miR-133a-3p was significantly downregulated in gefitinib-resistant NSCLC cells, and overexpression of miR-133a-3p could increase the sensitivity of cells to gefitinib. SPAG5 was identified as an important target gene of miR-133a-3p, which could reverse the miR-133a-3p-mediated gefitinib sensitivity.

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Knockdown of lncRNA HIF1A-AS2 increases drug sensitivity of SCLC cells in association with autophagy

Ebru Guclu et al.

Summary: Silencing lncRNA HIF1A-AS2 increased drug sensitivity and decreased autophagy in SCLC cells. Knockdown of HIF1A-AS2 affected the expression of genes related to drug resistance and autophagy, such as MRP1, HIF-1 alpha, and Beclin-1. The hypoxia-HIF1A-AS2-autophagy interaction was considered crucial in determining drug sensitivity in these cells.

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miR221 regulates TGF-β1-induced HSC activation through inhibiting autophagy by directly targeting LAMP2

Ran Cheng et al.

Summary: The study indicates that miR221 may regulate TGF-beta 1-induced HSC activation by inhibiting autolysosome function through direct targeting of LAMP2. The molecular mechanism of miR221 in regulating TGF-beta 1-induced HSC activation may provide novel insights into therapies to ameliorate the pathological progression of liver fibrosis.

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Targeting the PI3K/AKT/mTOR Signaling Pathway in Lung Cancer: An Update Regarding Potential Drugs and Natural Products

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Munehiro Kitada et al.

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Autophagy inhibition and microRNA-199a-5p upregulation in paclitaxel-resistant A549/T lung cancer cells

Tianjiao Zeng et al.

Summary: The study found that miR-199a-5p was upregulated in MDR lung cancer cells, inhibiting autophagy and increasing resistance to multiple chemotherapeutic drugs. Mechanistically, miR-199a-5p blocked autophagy by activating the PI3K/Akt/mTOR signaling pathway, inhibiting autophagy-related protein expression, and targeting p62 protein. This discovery may offer novel insights for future multidrug-resistant lung cancer chemotherapy.

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miR-133b inhibits cell proliferation, migration, and invasion of lung adenocarcinoma by targeting CDCA8

Chunxiu Hu et al.

Summary: The study revealed that CDCA8 was overexpressed in LUAD tissues while its upstream miRNA miR-133b was downregulated, and miR-133b could inhibit the proliferation, invasion, and migration of LUAD cells by targeting CDCA8.

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Selenium inhibits growth of trastuzumab-resistant human breast cancer cells via downregulation of Akt and beclin-1

Joohyun Woo et al.

Summary: The study investigated the effect of selenium on HER2-positive breast cancer cells in response to trastuzumab, showing that the combination of selenium and trastuzumab had an antitumor effect in trastuzumab-resistant breast cancer cells by downregulating phosphorylated Akt and beclin1-related autophagy.

PLOS ONE (2021)

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Article Oncology

MiR-194-5p enhances the sensitivity of nonsmall-cell lung cancer to doxorubicin through targeted inhibition of hypoxia-inducible factor-1

Mengning Xia et al.

Summary: MiR-194-5p enhances the sensitivity of NSCLC cells to DOX by directly inhibiting HIF-1, providing insights into potential treatments for drug-resistant NSCLC.

WORLD JOURNAL OF SURGICAL ONCOLOGY (2021)

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Review Immunology

Role of chaperone-mediated autophagy in the pathophysiology including pulmonary disorders

Yusuke Hosaka et al.

Summary: CMA is a form of autophagy characterized by the selective degradation of proteins, playing crucial roles in various organs and diseases, including cancer and pulmonary disorders. Understanding the CMA mechanism may lead to new treatment modalities for refractory disorders.

INFLAMMATION AND REGENERATION (2021)

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Article Oncology

miR-342-3p Regulates the Proliferation and Apoptosis of NSCLC Cells by Targeting BCL-2

Zhongjie Chen et al.

Summary: The study revealed that microRNA-342-3p is downregulated in nonsmall cell lung cancer compared to normal cells and tissues. Overexpression of microRNA-342-3p suppressed cell proliferation and promoted apoptosis by repressing the expression of B-cell lymphoma-2, suggesting it as a potential target for nonsmall cell lung cancer treatment.

TECHNOLOGY IN CANCER RESEARCH & TREATMENT (2021)

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Article Biotechnology & Applied Microbiology

MicroRNA-25-3p promotes cisplatin resistance in Non-small-cell lung carcinoma (NSCLC) through adjusting PTEN/PI3K/AKT route

Butong Sun et al.

Summary: The research found that miR-25-3p plays a crucial role in cisplatin resistance in NSCLC, accelerating drug tolerance by regulating the PTEN/PI3K/AKT signaling pathway.

BIOENGINEERED (2021)

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Article Oncology

MiR-30a sensitized lung cancer against neoadjuvant chemotherapy by depressing autophagy

Xiao Lin et al.

Summary: The study found that the low expression of miR-30a was closely related to malignant pathological characteristics and prognosis in NSCLC patients after neoadjuvant chemotherapy. Up-regulation of miR-30a can reduce the resistance of NSCLC cells to chemotherapy drugs, suppress chemotherapy-induced autophagy, and promote cell apoptosis.

JAPANESE JOURNAL OF CLINICAL ONCOLOGY (2021)

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Article Oncology

MicroRNA-32-5p inhibits epithelial-mesenchymal transition and metastasis in lung adenocarcinoma by targeting SMAD family 3

Jin-Xing Zhang et al.

Summary: The study found that miR-32-5p is downregulated in NSCLC tissues and inhibits the migration and invasion abilities of tumors by targeting SMAD3. miR-32-5p may be a potential therapeutic target for the treatment of lung adenocarcinoma.

JOURNAL OF CANCER (2021)

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Article Oncology

Overexpression of microRNA-124-5p sensitizes non-small cell lung cancer cells to treatment with 5-fluorouracil via AEG-1 regulation

Xiaoxia Tan et al.

Summary: The study revealed that miR-124-5p may regulate the chemotherapeutic sensitivity of NSCLC cells by reducing AEG-1 expression, indicating its potential as a promising biomarker or therapeutic target for patients with NSCLC.

ONCOLOGY LETTERS (2021)

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Article Oncology

Expression profile and diagnostic value of circRNAs in peripheral blood from patients with systemic lupus erythematosus

Qing Luo et al.

Summary: The study identified dysregulated circRNAs in peripheral blood of patients with SLE, with hsa_circ_0082688-hsa_circ_0082689 combination showing potential diagnostic value.

MOLECULAR MEDICINE REPORTS (2021)

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Article Cell Biology

MicroRNA-20a-5p suppresses tumor angiogenesis of non-small cell lung cancer through RRM2-mediated PI3K/Akt signaling pathway

Junlei Han et al.

Summary: miR-20a suppresses NSCLC growth by inhibiting the RRM2-mediated PI3K/Akt signaling pathway, serving as a potential tumor suppressor and molecular target for NSCLC treatment.

MOLECULAR AND CELLULAR BIOCHEMISTRY (2021)

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Review Biochemistry & Molecular Biology

History of the Selective Autophagy Research: How Did It Begin and Where Does It Stand Today?

Vladimir Kirkin

JOURNAL OF MOLECULAR BIOLOGY (2020)

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Review Immunology

The Controversial Role of Autophagy in Tumor Development: A Systematic Review

Bridilla Luiza Colhado Rodrigues et al.

IMMUNOLOGICAL INVESTIGATIONS (2020)

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Article Cell Biology

MicroRNA-30a Targets ATG5 and Attenuates Airway Fibrosis in Asthma by Suppressing Autophagy

Bin Bin Li et al.

INFLAMMATION (2020)

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Review Biochemistry & Molecular Biology

Autophagosome-Lysosome Fusion

Peter Lorincz et al.

JOURNAL OF MOLECULAR BIOLOGY (2020)

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Review Pharmacology & Pharmacy

Drug resistance to targeted therapeutic strategies in non-small cell lung cancer

Wen-juan Liu et al.

PHARMACOLOGY & THERAPEUTICS (2020)

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Review Oncology

At a glance: A history of autophagy and cancer

Xin Wen et al.

SEMINARS IN CANCER BIOLOGY (2020)

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Article Medicine, Research & Experimental

MiRNA-192-5p attenuates airway remodeling and autophagy in asthma by targeting MMP-16 and ATG7

Lili Lou et al.

BIOMEDICINE & PHARMACOTHERAPY (2020)

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Article Chemistry, Medicinal

Synthesis of PJOV56, a new quinoxalinyl-hydrazone derivative able to induce autophagy and apoptosis in colorectal cancer cells, and related compounds

Sarah Sant'Anna Maranhao et al.

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2020)

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Review Biochemistry & Molecular Biology

Autophagy and microbial pathogenesis

Matthew D. Keller et al.

CELL DEATH AND DIFFERENTIATION (2020)

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Article Biochemistry & Molecular Biology

Ganoderic acid DM induces autophagic apoptosis in non-small cell lung cancer cells by inhibiting the PI3K/Akt/mTOR activity

Junbo Xia et al.

CHEMICO-BIOLOGICAL INTERACTIONS (2020)

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Article Medicine, Research & Experimental

miR-373 inhibits autophagy and further promotes apoptosis of cholangiocarcinoma cells by targeting ULK1

Pin Lv et al.

KAOHSIUNG JOURNAL OF MEDICAL SCIENCES (2020)

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Article Medicine, Research & Experimental

miR-27a ameliorates chemoresistance of breast cancer cells by disruption of reactive oxygen species homeostasis and impairment of autophagy

Shinobu Ueda et al.

LABORATORY INVESTIGATION (2020)

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Article Medicine, Research & Experimental

MiR-27b suppresses epithelial ?mesenchymal transition and chemoresistance in lung cancer by targeting Snail1

Jun Zhang et al.

LIFE SCIENCES (2020)

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Review Biochemistry & Molecular Biology

Autophagy and autophagy-related proteins in cancer

Xiaohua Li et al.

MOLECULAR CANCER (2020)

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Review Oncology

Immunotherapeutic approaches for small-cell lung cancer

Wade T. Iams et al.

NATURE REVIEWS CLINICAL ONCOLOGY (2020)

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Article Biotechnology & Applied Microbiology

miR-1269b Drives Cisplatin Resistance of Human Non-Small Cell Lung Cancer via Modulating the PTEN/PI3K/AKT Signaling Pathway

Wu Yang et al.

ONCOTARGETS AND THERAPY (2020)

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Review Biochemistry & Molecular Biology

MiR-144: A New Possible Therapeutic Target and Diagnostic/Prognostic Tool in Cancers

Omid Kooshkaki et al.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2020)

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Article Cell Biology

Manipulation of selective macroautophagy by pathogens at a glance

Yingying Cong et al.

JOURNAL OF CELL SCIENCE (2020)

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Article Biotechnology & Applied Microbiology

Long Non-Coding RNA NNT-AS1 Contributes to Cisplatin Resistance via miR-1236-3p/ATG7 Axis in Lung Cancer Cells

Haifeng Wang et al.

ONCOTARGETS AND THERAPY (2020)

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Article Cell Biology

MicroRNA-30a targets BECLIN-1 to inactivate autophagy and sensitizes gastrointestinal stromal tumor cells to imatinib

Wei Chen et al.

CELL DEATH & DISEASE (2020)

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Article Oncology

Upregulation of microRNA-1 inhibits proliferation and metastasis of breast cancer

Jing Peng et al.

MOLECULAR MEDICINE REPORTS (2020)

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Review Oncology

Autophagy Regulation by the Translation Machinery and Its Implications in Cancer

Pilar Sarah Acevo-Rodriguez et al.

FRONTIERS IN ONCOLOGY (2020)

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Article Oncology

MiR-223 regulates autophagy associated with cisplatin resistance by targeting FBXW7 in human non-small cell lung cancer

Hui Wang et al.

CANCER CELL INTERNATIONAL (2020)

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Review Pharmacology & Pharmacy

Nanomaterials for Autophagy-Related miRNA-34a Delivery in Cancer Treatment

Priyanka Sharma et al.

FRONTIERS IN PHARMACOLOGY (2020)

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Review Biochemistry & Molecular Biology

The Latest Findings of PD-1/PD-L1 Inhibitor Application in Gynecologic Cancers

Omid Kooshkaki et al.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2020)

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Article Biotechnology & Applied Microbiology

MiR-221/222 promote migration and invasion, and inhibit autophagy and apoptosis by modulating ATG10 in aggressive papillary thyroid carcinoma

Hao Shen et al.

3 BIOTECH (2020)

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Review Oncology

Exosomal MicroRNAs and Organotropism in Breast Cancer Metastasis

Grace L. Wong et al.

CANCERS (2020)

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Article Cell Biology

MicroRNA-143 sensitizes acute myeloid leukemia cells to cytarabine via targeting ATG7-and ATG2B-dependent autophagy

Hao Zhang et al.

AGING-US (2020)

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Review Chemistry, Medicinal

Recent updates on the resistance mechanisms to epidermal growth factor receptor tyrosine kinase inhibitors and resistance reversion strategies in lung cancer

Surya K. Tripathi et al.

MEDICINAL RESEARCH REVIEWS (2020)

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Article Oncology

Chaperone-mediated autophagy receptor modulates tumor growth and chemoresistance in non-small cell lung cancer

Akihiro Ichikawa et al.

CANCER SCIENCE (2020)

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Review Cell Biology

Autophagy-mediating microRNAs in cancer chemoresistance

Yuanming Jing et al.

CELL BIOLOGY AND TOXICOLOGY (2020)

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Review Oncology

Autophagy-related MicroRNAs in chronic lung diseases and lung cancer

Samaneh Rezaei et al.

CRITICAL REVIEWS IN ONCOLOGY HEMATOLOGY (2020)

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Review Pharmacology & Pharmacy

MicroRNAs as mediators of drug resistance mechanisms

Andrea Lampis et al.

CURRENT OPINION IN PHARMACOLOGY (2020)

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Article Oncology

Beclin-1 expression is associated with prognosis in a Bcl-2-dependent manner in non-small cell lung cancer

Hailei Du et al.

ONCOLOGY LETTERS (2020)

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Review Cell Biology

Microautophagy - distinct molecular mechanisms handle cargoes of many sizes

Sebastian Schuck

JOURNAL OF CELL SCIENCE (2020)

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Article Oncology

Exosomal miR-141 promotes tumor angiogenesis via KLF12 in small cell lung cancer

Shuangshuang Mao et al.

JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH (2020)

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Review Biochemistry & Molecular Biology

MicroRNAs involved in drug resistance of breast cancer by regulating autophagy

Nan Wen et al.

JOURNAL OF ZHEJIANG UNIVERSITY-SCIENCE B (2020)

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Article Biochemistry & Molecular Biology

Novel, abundant Drosha isoforms are deficient in miRNA processing in cancer cells

Lisheng Dai et al.

RNA BIOLOGY (2020)

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Review Cell Biology

The Role of Chaperone-Mediated Autophagy in Cell Cycle Control and Its Implications in Cancer

Marina Andrade-Tomaz et al.

CELLS (2020)

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Article Cell Biology

Novel Insights into the Cellular Localization and Regulation of the Autophagosomal Proteins LC3A, LC3B and LC3C

Marius W. Baeken et al.

CELLS (2020)

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Review Oncology

The Double-Edge Sword of Autophagy in Cancer: From Tumor Suppression to Pro-tumor Activity

Rodolfo Chavez-Dominguez et al.

FRONTIERS IN ONCOLOGY (2020)

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Article

miR-708-5p enhances erlotinib/paclitaxel efficacy and overcomes chemoresistance in lung cancer cells

Nicholas J. Monteleone et al.

Oncotarget (2020)

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Article Oncology

The Roles of Beclin 1 Expression in Gastric Cancer: A Marker for Carcinogenesis, Aggressive Behaviors and Favorable Prognosis, and a Target of Gene Therapy

Hua-chuan Zheng et al.

FRONTIERS IN ONCOLOGY (2020)

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Review Cell Biology

The Role of Autophagy in Gastric Cancer Chemoresistance: Friend or Foe?

Jing-Li Xu et al.

FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY (2020)

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Article Oncology

Involvement of the MicroRNA-1-LITAF Axis in Gastric Cancer Cell Growth and Invasion

Yen-Chih Chen et al.

ANTICANCER RESEARCH (2020)

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Article Biochemistry & Molecular Biology

miR-410 induces both epithelial-mesenchymal transition and radioresistance through activation of the PI3K/mTOR pathway in non-small cell lung cancer

Yue Yuan et al.

SIGNAL TRANSDUCTION AND TARGETED THERAPY (2020)

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Article Multidisciplinary Sciences

A High-Throughput Small Molecule Screen Identifies Ouabain as Synergistic with miR-34a in Killing Lung Cancer Cells

Rajesha Rupaimoole et al.

ISCIENCE (2020)

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Article Oncology

Prognostic Role of Circulating Exosomal miR-425-3p for the Response of NSCLC to Platinum-Based Chemotherapy

Daolu Yuwen et al.

CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION (2019)

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Article Biochemistry & Molecular Biology

High expression of miR-510 was associated with CGG expansion located at upstream of FMR1 into full mutation

Zahra Fazeli et al.

JOURNAL OF CELLULAR BIOCHEMISTRY (2019)

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Article Medicine, Research & Experimental

MicroRNA-145 replacement effect on growth and migration inhibition in lung cancer cell line

Navaz Sadeghiyeh et al.

BIOMEDICINE & PHARMACOTHERAPY (2019)

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Article Oncology

The PVT1/miR-216b/Beclin-1 regulates cisplatin sensitivity of NSCLC cells via modulating autophagy and apoptosis

Liangfeng Chen et al.

CANCER CHEMOTHERAPY AND PHARMACOLOGY (2019)

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Article Cell Biology

Phosphorylation of Syntaxin 17 by TBK1 Controls Autophagy Initiation

Suresh Kumar et al.

DEVELOPMENTAL CELL (2019)

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Article Oncology

MiR-223-3p functions as a tumor suppressor in lung squamous cell carcinoma by miR-223-3p-mutant p53 regulatory feedback loop

Peng Luo et al.

JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH (2019)

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Review Oncology

MicroRNA-34 family: a potential tumor suppressor and therapeutic candidate in cancer

Lu Zhang et al.

JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH (2019)

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Article Oncology

Identification of tumor suppressor miRNAs by integrative miRNA and mRNA sequencing of matched tumor-normal samples in lung adenocarcinoma

Namhee Yu et al.

MOLECULAR ONCOLOGY (2019)

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Review Oncology

The role and mechanisms of action of microRNAs in cancer drug resistance

Wengong Si et al.

CLINICAL EPIGENETICS (2019)

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Article Genetics & Heredity

Long non-coding RNA PVT1 promotes autophagy as ceRNA to target ATG3 by sponging microRNA-365 in hepatocellular carcinoma

Liang Yang et al.

GENE (2019)

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Article Cell Biology

Microrna-130a Downregulates HCV Replication through an atg5-Dependent Autophagy Pathway

Xiaoqiong Duan et al.

CELLS (2019)

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Article Oncology

MiR-7-5p-mediated downregulation of PARP1 impacts DNA homologous recombination repair and resistance to doxorubicin in small cell lung cancer

Jinzhi Lai et al.

BMC CANCER (2019)

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Article Oncology

Quantifying Argonaute 2 (Ago2) expression to stratify breast cancer

M. C. Casey et al.

BMC CANCER (2019)

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Article Cell Biology

MiR-34b-3p represses cell proliferation, cell cycle progression and cell apoptosis in non-small-cell lung cancer (NSCLC) by targeting CDK4

Hongxiang Feng et al.

JOURNAL OF CELLULAR AND MOLECULAR MEDICINE (2019)

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Article Multidisciplinary Sciences

MicroRNA-130b functions as an oncomiRNA in non-small cell lung cancer by targeting tissue inhibitor of metalloproteinase-2

Takayuki Hirono et al.

SCIENTIFIC REPORTS (2019)

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Article Medicine, Research & Experimental

miR-150-5p Inhibits Non-Small-Cell Lung Cancer Metastasis and Recurrence by Targeting HMGA2 and β-Catenin Signaling

Fu-Qiang Dai et al.

MOLECULAR THERAPY-NUCLEIC ACIDS (2019)

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Review Cell Biology

A Comprehensive Review of Autophagy and Its Various Roles in Infectious, Non-Infectious, and Lifestyle Diseases: Current Knowledge and Prospects for Disease Prevention, Novel Drug Design, and Therapy

Rekha Khandia et al.

CELLS (2019)

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Article Biochemistry & Molecular Biology

MiR-207 inhibits autophagy and promotes apoptosis of cardiomyocytes by directly targeting LAMP2 in type 2 diabetic cardiomyopathy

Ruinan Xing et al.

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2019)

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Article Oncology

Dysregulation of the miRNA biogenesis components DICER1, DROSHA, DGCR8 and AGO2 in clear cell renal cell carcinoma in both a Korean cohort and the cancer genome atlas kidney clear cell carcinoma cohort

Sang Su Lee et al.

ONCOLOGY LETTERS (2019)

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Article Nanoscience & Nanotechnology

Drug Nanorod-Mediated Intracellular Delivery of microRNA-101 for Self-sensitization via Autophagy Inhibition

Xiaofei Xin et al.

NANO-MICRO LETTERS (2019)

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Article Oncology

Crosstalk between let-7a-5p and BCL-xL in the Initiation of Toxic Autophagy in Lung Cancer

Shuyin Duan et al.

MOLECULAR THERAPY-ONCOLYTICS (2019)

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Article Oncology

Cancer Progress and Priorities: Lung Cancer

Matthew B. Schabath et al.

CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION (2019)

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Review Immunology

LC3-associated phagocytosis: host defense and microbial response

Sandeep Upadhyay et al.

CURRENT OPINION IN IMMUNOLOGY (2019)

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Article Cell Biology

MicroRNA-421 confers paclitaxel resistance by binding to the KEAP1 3′UTR and predicts poor survival in non-small cell lung cancer

Fu-Gang Duan et al.

CELL DEATH & DISEASE (2019)

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Article Cell Biology

Prognostic implications of autophagy-associated gene signatures in non-small cell lung cancer

Yang Liu et al.

AGING-US (2019)

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Article Oncology

LncRNA BLACAT1 is involved in chemoresistance of non-small cell lung cancer cells by regulating autophagy

Feng-Xiang Huang et al.

INTERNATIONAL JOURNAL OF ONCOLOGY (2019)

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Article Cell Biology

Effects of microRNA-513b on cell proliferation, apoptosis, invasion, and migration by targeting HMGB3 through regulation of mTOR signaling pathway in non-small-cell lung cancer

Jiying Wang et al.

JOURNAL OF CELLULAR PHYSIOLOGY (2019)

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Review Oncology

Emerging insights of tumor heterogeneity and drug resistance mechanisms in lung cancer targeted therapy

Zuan-Fu Lim et al.

JOURNAL OF HEMATOLOGY & ONCOLOGY (2019)

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Review Cell Biology

EMT Transition States during Tumor Progression and Metastasis

Ievgenia Pastushenko et al.

TRENDS IN CELL BIOLOGY (2019)

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Article Chemistry, Multidisciplinary

miR-124 and miR-142 enhance cisplatin sensitivity of non-small cell lung cancer cells through repressing autophagy via directly targeting SIRT1

Xiang Song et al.

RSC ADVANCES (2019)

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Review Pharmacology & Pharmacy

MicroRNAs in non-small cell lung cancer: Gene regulation, impact on cancer cellular processes, and therapeutic potential

Hannah Petrek et al.

PHARMACOLOGY RESEARCH & PERSPECTIVES (2019)

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Article Biochemistry & Molecular Biology

DNA methylation regulated microRNAs in human cervical cancer

Vinay K. Varghese et al.

MOLECULAR CARCINOGENESIS (2018)

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Review Oncology

Lung cancer epigenetics: From knowledge to applications

Michael Duruisseaux et al.

SEMINARS IN CANCER BIOLOGY (2018)

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Article Oncology

MicroRNA-20a promotes proliferation and invasion by directly targeting early growth response 2 in non-small cell lung carcinoma

Lai Wei et al.

ONCOLOGY LETTERS (2018)

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Article Biotechnology & Applied Microbiology

Co-delivery of insulin-like growth factor 1 receptor specific siRNA and doxorubicin using chitosan-based nanoparticles enhanced anticancer efficacy in A549 lung cancer cell line

Hajar Shali et al.

ARTIFICIAL CELLS NANOMEDICINE AND BIOTECHNOLOGY (2018)

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Article Oncology

Circulating microRNAs associated with prolonged overall survival in lung cancer patients treated with nivolumab

Ann Rita Halvorsen et al.

ACTA ONCOLOGICA (2018)

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Article Medicine, General & Internal

miR-181b inhibits chemoresistance in cisplatin-resistant H446 small cell lung cancer cells by targeting Bcl-2

Hui-Ning Liu et al.

ARCHIVES OF MEDICAL SCIENCE (2018)

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Article Oncology

miRNA 146a promotes chemotherapy resistance in lung cancer cells by targeting DNA damage inducible transcript 3 (CHOP)

Wenfeng Tan et al.

CANCER LETTERS (2018)

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Article Cell Biology

MicroRNA-1 overexpression increases chemosensitivity of non-small cell lung cancer cells by inhibiting autophagy related 3-mediated autophagy

Li Hua et al.

CELL BIOLOGY INTERNATIONAL (2018)

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Article Cell Biology

MiR-99a Enhances the Radiation Sensitivity of Non-Small Cell Lung Cancer by Targeting mTOR

Hang Yin et al.

CELLULAR PHYSIOLOGY AND BIOCHEMISTRY (2018)

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Review Oncology

MicroRNA Key to Angiogenesis Regulation: miRNA Biology and Therapy

Ankit Tiwari et al.

CURRENT CANCER DRUG TARGETS (2018)

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Review Biochemistry & Molecular Biology

MicroRNAs associated with therapy of non-small cell lung cancer

Junmi Lu et al.

INTERNATIONAL JOURNAL OF BIOLOGICAL SCIENCES (2018)

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Article Cell Biology

The miR-3127-5p/p-STAT3 axis up-regulates PD-L1 inducing chemoresistance in non-small-cell lung cancer

Dongfang Tang et al.

JOURNAL OF CELLULAR AND MOLECULAR MEDICINE (2018)

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Article Oncology

MicroRNA-378 enhances migration and invasion in cervical cancer by directly targeting autophagy-related protein 12

Dongmei Tan et al.

MOLECULAR MEDICINE REPORTS (2018)

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Article Agriculture, Dairy & Animal Science

miR-26a suppresses autophagy in swine Sertoli cells by targeting ULK2

M. Ran et al.

REPRODUCTION IN DOMESTIC ANIMALS (2018)

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Article Oncology

Aberrant microRNA-137 promoter methylation is associated with lymph node metastasis and poor clinical outcomes in non-small cell lung cancer

Lingfeng Min et al.

ONCOLOGY LETTERS (2018)

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Article Cell Biology

TNFAIP8 promotes the proliferation and cisplatin chemoresistance of non-small cell lung cancer through MDM2/p53 pathway

Ying Xing et al.

CELL COMMUNICATION AND SIGNALING (2018)

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Article Cell Biology

MicroRNA-128a represses chondrocyte autophagy and exacerbates knee osteoarthritis by disrupting Atg12

Wei-Shiung Lian et al.

CELL DEATH & DISEASE (2018)

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Article Pharmacology & Pharmacy

Evaluation of Flavonoid Derivative and Doxorubicin Effects in Lung Cancer Cells (A549) Using Differential Pulse Voltammetry Method

Mohammad Amjadi et al.

ADVANCED PHARMACEUTICAL BULLETIN (2018)

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Review Multidisciplinary Sciences

The biology and management of non-small cell lung cancer

Roy S. Herbst et al.

NATURE (2018)

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Article Cell Biology

miR-202 Enhances the Anti-Tumor Effect of Cisplatin on Non-Small Cell Lung Cancer by Targeting the Ras/MAPK Pathway

Wei Sun et al.

CELLULAR PHYSIOLOGY AND BIOCHEMISTRY (2018)

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Article Oncology

Hypermethylation of miRNA-589 promoter leads to upregulation of HDAC5 which promotes malignancy in non-small cell lung cancer

Changhong Liu et al.

INTERNATIONAL JOURNAL OF ONCOLOGY (2017)

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Article Oncology

Epigenetic silencing of miR-493 increases the resistance to cisplatin in lung cancer by targeting tongue cancer resistance-related protein 1(TCRP1)

Yixue Gu et al.

JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH (2017)

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Review Medicine, General & Internal

Lung cancer: current therapies and new targeted treatments

Fred R. Hirsch et al.

LANCET (2017)

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Review Oncology

Pharmacogenomics of platinum-based chemotherapy in non-small cell lung cancer: focusing on DNA repair systems

Yi Xiong et al.

MEDICAL ONCOLOGY (2017)

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Article Oncology

CISD2 promotes the proliferation of glioma cells via suppressing beclin-1-mediated autophagy and is targeted by microRNA-449a

Ai-Gang Sun et al.

MOLECULAR MEDICINE REPORTS (2017)

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Review Biotechnology & Applied Microbiology

MicroRNA therapeutics: towards a new era for the management of cancer and other diseases

Rajesha Rupaimoole et al.

NATURE REVIEWS DRUG DISCOVERY (2017)

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Article Oncology

Knockdown of lncRNA-XIST enhances the chemosensitivity of NSCLC cells via suppression of autophagy

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ONCOLOGY REPORTS (2017)

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Review Oncology

miRNAs as Biomarkers and Therapeutic Targets in Non-Small Cell Lung Cancer: Current Perspectives

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TARGETED ONCOLOGY (2017)

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Review Oncology

A new insight on reciprocal relationship between microRNA expression and epigenetic modifications in human lung cancer

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TUMOR BIOLOGY (2017)

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Article Oncology

MALAT1-miR-101-SOX9 feedback loop modulates the chemo-resistance of lung cancer cell to DDP via Wnt signaling pathway

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ONCOTARGET (2017)

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Article Oncology

MicroRNA profiling associated with non-small cell lung cancer: next generation sequencing detection, experimental validation, and prognostic value

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ONCOTARGET (2017)

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Article Multidisciplinary Sciences

Low Frequency Magnetic Fields Induce Autophagy-associated Cell Death in Lung Cancer through miR-486-mediated Inhibition of Akt/mTOR Signaling Pathway

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SCIENTIFIC REPORTS (2017)

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Article Cell Biology

被撤回的出版物: MiR-34a Promotes Apoptosis and Inhibits Autophagy by Targeting HMGB1 in Acute Myeloid Leukemia Cells (Retracted article. See vol. 56, pg. 83, 2022)

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CELLULAR PHYSIOLOGY AND BIOCHEMISTRY (2017)

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Article Cell Biology

Effect of microRNA-135a on Cell Proliferation, Migration, Invasion, Apoptosis and Tumor Angiogenesis Through the IGF-1/PI3K/Akt Signaling Pathway in Non-Small Cell Lung Cancer

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CELLULAR PHYSIOLOGY AND BIOCHEMISTRY (2017)

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Article Cell Biology

Intensified Beclin-1 Mediated by Low Expression of Mir-30a-5p Promotes Chemoresistance in Human Small Cell Lung Cancer

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CELLULAR PHYSIOLOGY AND BIOCHEMISTRY (2017)

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Article Oncology

miR-181c contributes to cisplatin resistance in non-small cell lung cancer cells by targeting Wnt inhibition factor 1

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CANCER CHEMOTHERAPY AND PHARMACOLOGY (2017)

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Article Biotechnology & Applied Microbiology

MiR-9 enhances the sensitivity of A549 cells to cisplatin by inhibiting autophagy

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BIOTECHNOLOGY LETTERS (2017)

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Article Cell Biology

MiR-142-3p Overexpression Increases Chemo-Sensitivity of NSCLC by Inhibiting HMG B1-Mediated Autophagy

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CELLULAR PHYSIOLOGY AND BIOCHEMISTRY (2017)

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Review Biochemistry & Molecular Biology

mTOR Signaling in Growth, Metabolism, and Disease

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CELL (2017)

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Article Oncology

miR-15a enhances the anticancer effects of cisplatin in the resistant non-small cell lung cancer cells

Vildan Bozok Cetintas et al.

TUMOR BIOLOGY (2016)

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Article Biochemistry & Molecular Biology

miR-487b-5p Regulates Temozolomide Resistance of Lung Cancer Cells Through LAMP2-Medicated Autophagy

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DNA AND CELL BIOLOGY (2016)

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Article Genetics & Heredity

miR-181a suppresses autophagy and sensitizes gastric cancer cells to cisplatin

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GENE (2016)

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Article Cell Biology

Autophagy provides metabolic substrates to maintain energy charge and nucleotide pools in Ras-driven lung cancer cells

Jessie Yanxiang Guo et al.

GENES & DEVELOPMENT (2016)

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Article Oncology

Plasma miRNAs in predicting radiosensitivity in non-small cell lung cancer

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TUMOR BIOLOGY (2016)

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Article Peripheral Vascular Disease

Tumor-derived microRNA-494 promotes angiogenesis in non-small cell lung cancer

Guangmei Mao et al.

ANGIOGENESIS (2015)

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Article Oncology

Inhibition of miR-191 contributes to radiation-resistance of two lung cancer cell lines by altering autophagy activity

Zhenkuan Liu et al.

CANCER CELL INTERNATIONAL (2015)

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Article Cell Biology

miR-16 targets Bcl-2 in paclitaxel-resistant lung cancer cells and overexpression of miR-16 along with miR-17 causes unprecedented sensitivity by simultaneously modulating autophagy and apoptosis

Abhisek Chatterjee et al.

CELLULAR SIGNALLING (2015)

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Article Oncology

AMPK-independent autophagy promotes radioresistance of human tumor cells under clinical relevant hypoxia in vitro

Hassan Chaachouay et al.

RADIOTHERAPY AND ONCOLOGY (2015)

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Article Oncology

Chitosan nanoparticle-mediated delivery of miRNA-34a decreases prostate tumor growth in the bone and its expression induces non-canonical autophagy

Sanchaika Gaur et al.

ONCOTARGET (2015)

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Article Oncology

MiR-200b regulates autophagy associated with chemoresistance in human lung adenocarcinoma

Banzhou Pan et al.

ONCOTARGET (2015)

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Article Multidisciplinary Sciences

Hypoxia-induced autophagy mediates cisplatin resistance in lung cancer cells

Hui-Mei Wu et al.

SCIENTIFIC REPORTS (2015)

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Article Multidisciplinary Sciences

Autophagosome Proteins LC3A, LC3B and LC3C Have Distinct Subcellular Distribution Kinetics and Expression in Cancer Cell Lines

Michael I. Koukourakis et al.

PLOS ONE (2015)

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Article Oncology

Mir-24-3p downregulation contributes to VP16-DDP resistance in small-cell lung cancer by targeting ATG4A

Banzhou Pan et al.

ONCOTARGET (2015)

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Article Multidisciplinary Sciences

miR-17-5p Downregulation Contributes to Paclitaxel Resistance of Lung Cancer Cells through Altering Beclin1 Expression

Abhisek Chatterjee et al.

PLOS ONE (2014)

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Article Multidisciplinary Sciences

A dual role for autophagy in a murine model of lung cancer

Shuan Rao et al.

NATURE COMMUNICATIONS (2014)

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Article Oncology

MicroRNA-25 regulates chemoresistance-associated autophagy in breast cancer cells, a process modulated by the natural autophagy inducer isoliquiritigenin

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ONCOTARGET (2014)

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Review Medicine, General & Internal

Cisplatin versus carboplatin in combination with third-generation drugs for advanced non-small cell lung cancer

Tiago B. de Castria et al.

COCHRANE DATABASE OF SYSTEMATIC REVIEWS (2013)

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