4.7 Article

NewWave: a scalable R/Bioconductor package for the dimensionality reduction and batch effect removal of single-cell RNA-seq data

期刊

BIOINFORMATICS
卷 38, 期 9, 页码 2648-2650

出版社

OXFORD UNIV PRESS
DOI: 10.1093/bioinformatics/btac149

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资金

  1. AIRC Foundation for Cancer Research in Italy [AIRC 21837]
  2. National Cancer Institute of the National Institutes of Health [2U24CA180996]
  3. Chan Zuckerberg Initiative DAF [CZF2019-002443]
  4. Silicon Valley Community Foundation
  5. University of Padova

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NewWave is a scalable software package for dimensionality reduction and batch effect removal of single-cell RNA sequencing data. It utilizes mini-batch optimization to achieve scalability and can handle large-scale datasets.
We present NewWave, a scalable R/Bioconductor package for the dimensionality reduction and batch effect removal of single-cell RNA sequencing data. To achieve scalability, NewWave uses mini-batch optimization and can work with out-of-memory data, enabling users to analyze datasets with millions of cells.

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