期刊
BIOINFORMATICS
卷 38, 期 9, 页码 2648-2650出版社
OXFORD UNIV PRESS
DOI: 10.1093/bioinformatics/btac149
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资金
- AIRC Foundation for Cancer Research in Italy [AIRC 21837]
- National Cancer Institute of the National Institutes of Health [2U24CA180996]
- Chan Zuckerberg Initiative DAF [CZF2019-002443]
- Silicon Valley Community Foundation
- University of Padova
NewWave is a scalable software package for dimensionality reduction and batch effect removal of single-cell RNA sequencing data. It utilizes mini-batch optimization to achieve scalability and can handle large-scale datasets.
We present NewWave, a scalable R/Bioconductor package for the dimensionality reduction and batch effect removal of single-cell RNA sequencing data. To achieve scalability, NewWave uses mini-batch optimization and can work with out-of-memory data, enabling users to analyze datasets with millions of cells.
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