相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。Amyloid-β dimers in the absence of plaque pathology impair learning and synaptic plasticity
Andreas Mueller-Schiffmann et al.
BRAIN (2016)
Characterization of Aβ Monomers through the Convergence of Ensemble Properties among Simulations with Multiple Force Fields
David J. Rosenman et al.
JOURNAL OF PHYSICAL CHEMISTRY B (2016)
Impact of the A2V Mutation on the Heterozygous and Homozygous Aβ1-40 Dimer Structures from Atomistic Simulations
Phuong H. Nguyen et al.
ACS CHEMICAL NEUROSCIENCE (2016)
Critical Nucleus Structure and Aggregation Mechanism of the C-terminal Fragment of Copper-Zinc Superoxide Dismutase Protein
Yu Zou et al.
ACS CHEMICAL NEUROSCIENCE (2016)
An Account of Amyloid Oligomers: Facts and Figures Obtained from Experiments and Simulations
Luitgard Nagel-Steger et al.
CHEMBIOCHEM (2016)
Revisiting supersaturation as a factor determining amyloid fibrillation
Masatomo So et al.
CURRENT OPINION IN STRUCTURAL BIOLOGY (2016)
Lattice model for amyloid peptides: OPEP force field parametrization and applications to the nucleus size of Alzheimer's peptides
Thanh Thuy Tran et al.
JOURNAL OF CHEMICAL PHYSICS (2016)
Advances in the Simulation of Protein Aggregation at the Atomistic Scale
Martin Carballo-Pacheco et al.
JOURNAL OF PHYSICAL CHEMISTRY B (2016)
Amyloid β-Protein C-Terminal Fragments: Formation of Cylindrins and β-Barrels
Thanh D. Do et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2016)
Determination of critical nucleation number for a single nucleation amyloid-β aggregation model
Preetam Ghosh et al.
MATHEMATICAL BIOSCIENCES (2016)
A2T and A2V A peptides exhibit different aggregation kinetics, primary nucleation, morphology, structure, and LTP inhibition
Brian Murray et al.
PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS (2016)
Evaluation of the coarse-grained OPEP force field for protein-protein docking
Philipp Kynast et al.
BMC BIOPHYSICS (2016)
Quantitative analysis of intrinsic and extrinsic factors in the aggregation mechanism of Alzheimer-associated Aβ-peptide
Georg Meisl et al.
SCIENTIFIC REPORTS (2016)
An Early Folding Contact between Phe19 and Leu34 is Critical for Amyloid-β Oligomer Toxicity
Anand K. Das et al.
ACS CHEMICAL NEUROSCIENCE (2015)
Amyloid β-Protein Assembly: Differential Effects of the Protective A2T Mutation and Recessive A2V Familial Alzheimer's Disease Mutation
Xueyun Zheng et al.
ACS CHEMICAL NEUROSCIENCE (2015)
Alzheimer's Protective A2T Mutation Changes the Conformational Landscape of the Aβ1-42 Monomer Differently Than Does the A2V Mutation
Payel Das et al.
BIOPHYSICAL JOURNAL (2015)
Amyloid β Protein and Alzheimer's Disease: When Computer Simulations Complement Experimental Studies
Jessica Nasica-Labouze et al.
CHEMICAL REVIEWS (2015)
Combined Experimental and Simulation Studies Suggest a Revised Mode of Action of the Anti-Alzheimer Disease Drug NQ-Trp
Olivia Berthoumieu et al.
CHEMISTRY-A EUROPEAN JOURNAL (2015)
The Dependence of Amyloid-β Dynamics on Protein Force Fields and Water Models
Arun Kumar Somavarapu et al.
CHEMPHYSCHEM (2015)
Inhibition of protein aggregation and amyloid formation by small molecules
Andrew J. Doig et al.
CURRENT OPINION IN STRUCTURAL BIOLOGY (2015)
Molecular structure of the NQTrp inhibitor with the Alzheimer Aβ1-28 monomer
Bogdan Tarus et al.
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (2015)
Picosecond dissociation of amyloid fibrils with infrared laser: A nonequilibrium simulation study
Man Hoang Viet et al.
JOURNAL OF CHEMICAL PHYSICS (2015)
Protein Simulations in Fluids: Coupling the OPEP Coarse-Grained Force Field with Hydrodynamics
Fabio Sterpone et al.
JOURNAL OF CHEMICAL THEORY AND COMPUTATION (2015)
Are coarse-grained models apt to detect protein thermal stability? The case of OPEP force field
Maria Kalimeri et al.
JOURNAL OF NON-CRYSTALLINE SOLIDS (2015)
Structures of the Alzheimer's Wild-Type Aβ1-40 Dimer from Atomistic Simulations
Bogdan Tarus et al.
JOURNAL OF PHYSICAL CHEMISTRY B (2015)
Folding Atomistic Proteins in Explicit Solvent Using Simulated Tempering
Tong Zhang et al.
JOURNAL OF PHYSICAL CHEMISTRY B (2015)
Primary Nucleation Kinetics of Short Fibril-Forming Amyloidogenic Peptides
Jurriaan A. Luiken et al.
JOURNAL OF PHYSICAL CHEMISTRY B (2015)
Varied Probability of Staying Collapsed/Extended at the Conformational Equilibrium of Monomeric Aβ40 and Aβ42
Wanling Song et al.
SCIENTIFIC REPORTS (2015)
A Genome-wide Gene-Expression Analysis and Database in Transgenic Mice during Development of Amyloid or Tau Pathology
Mar Matarin et al.
CELL REPORTS (2015)
The inverted free energy landscape of an intrinsically disordered peptide by simulations and experiments
Daniele Granata et al.
SCIENTIFIC REPORTS (2015)
Atomic and Dynamic Insights into the Beneficial Effect of the 1,4-Naphthoquinon-2-yl-L-tryptophan Inhibitor on Alzheimer's Aβ1-42 Dimer in Terms of Aggregation and Toxicity
Tong Zhang et al.
ACS CHEMICAL NEUROSCIENCE (2014)
Effect of the English Familial Disease Mutation (H6R) on the Monomers and Dimers of Aβ40 and Aβ42
Man Hoang Viet et al.
ACS CHEMICAL NEUROSCIENCE (2014)
The OPEP protein model: from single molecules, amyloid formation, crowding and hydrodynamics to DNA/RNA systems
Fabio Sterpone et al.
CHEMICAL SOCIETY REVIEWS (2014)
The Peculiar Role of the A2V Mutation in Amyloid-β (Aβ) 1-42 Molecular Assembly
Massimo Messa et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2014)
Molecular Mechanisms of Alzheimer Disease Protection by the A673T Allele of Amyloid Precursor Protein
Janice A. Maloney et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2014)
The Alzheimer Disease Protective Mutation A2T Modulates Kinetic and Thermodynamic Properties of Amyloid-β (Aβ) Aggregation
Iryna Benilova et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2014)
Improved PEP-FOLD Approach for Peptide and Miniprotein Structure Prediction
Yimin Shen et al.
JOURNAL OF CHEMICAL THEORY AND COMPUTATION (2014)
Simulations of Protein Aggregation: Insights from Atomistic and Coarse-Grained Models
Alex Morriss-Andrews et al.
JOURNAL OF PHYSICAL CHEMISTRY LETTERS (2014)
A Simple Lattice Model That Captures Protein Folding, Aggregation and Amyloid Formation
Sanne Abeln et al.
PLOS ONE (2014)
Crucial role of nonspecific interactions in amyloid nucleation
Andela Saric et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2014)
Molecular Structures of Amyloid and Prion Fibrils: Consensus versus Controversy
Robert Tycko et al.
ACCOUNTS OF CHEMICAL RESEARCH (2013)
Effect of the Tottori Familial Disease Mutation (D7N) on the Monomers and Dimers of Aβ40 and Aβ42
Man Hoang Viet et al.
ACS CHEMICAL NEUROSCIENCE (2013)
Perspective on the Martini model
Siewert J. Marrink et al.
CHEMICAL SOCIETY REVIEWS (2013)
Importance of the Ion-Pair Interactions in the OPEP Coarse-Grained Force Field: Parametrization and Validation
Fabio Sterpone et al.
JOURNAL OF CHEMICAL THEORY AND COMPUTATION (2013)
Aβ Monomers Transiently Sample Oligomer and Fibril-Like Configurations: Ensemble Characterization Using a Combined MD/NMR Approach
David J. Rosenman et al.
JOURNAL OF MOLECULAR BIOLOGY (2013)
Conformational Ensemble and Polymorphism of the All-Atom Alzheimer's Aβ37-42 Amyloid Peptide Oligomers
Phuong H. Nguyen et al.
JOURNAL OF PHYSICAL CHEMISTRY B (2013)
Single Point Mutation Alters the Microstate Dynamics of Amyloid β-Protein Aβ42 as Revealed by Dihedral Dynamics Analyses
Liang Xu et al.
JOURNAL OF PHYSICAL CHEMISTRY B (2013)
Molecular Mechanism of the Inhibition of EGCG on the Alzheimer Aβ1-42 Dimer
Tong Zhang et al.
JOURNAL OF PHYSICAL CHEMISTRY B (2013)
Aggregate Geometry in Amyloid Fibril Nucleation
Anders Irback et al.
PHYSICAL REVIEW LETTERS (2013)
Nucleation Process of a Fibril Precursor in the C-Terminal Segment of Amyloid-β
Fahimeh Baftizadeh et al.
PHYSICAL REVIEW LETTERS (2013)
Proliferation of amyloid-β42 aggregates occurs through a secondary nucleation mechanism
Samuel I. A. Cohen et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2013)
Familial Alzheimer's Disease Mutations Differentially Alter Amyloid β-Protein Oligomerization
Megan Murray Gessel et al.
ACS CHEMICAL NEUROSCIENCE (2012)
Effects of Familial Mutations on the Monomer Structure of Aβ42
Yu-Shan Lin et al.
BIOPHYSICAL JOURNAL (2012)
Novel APP/Aß mutation K16N produces highly toxic heteromeric Aß oligomers
Daniela Kaden et al.
EMBO MOLECULAR MEDICINE (2012)
New method for determining size of critical nucleus of fibril formation of polypeptide chains
Nguyen Truong Co et al.
JOURNAL OF CHEMICAL PHYSICS (2012)
Driving Forces and Structural Determinants of Steric Zipper Peptide Oligomer Formation Elucidated by Atomistic Simulations
Dirk Matthes et al.
JOURNAL OF MOLECULAR BIOLOGY (2012)
The Coarse-Grained OPEP Force Field for Non-Amyloid and Amyloid Proteins
Yassmine Chebaro et al.
JOURNAL OF PHYSICAL CHEMISTRY B (2012)
Distinct Dimerization for Various Alloforms of the Amyloid-Beta Protein: Aβ1-40, Aβ1-42, and Aβ1-40(D23N)
Sebastien Cote et al.
JOURNAL OF PHYSICAL CHEMISTRY B (2012)
Structures of Aβ17-42 Trimers in Isolation and with Five Small-Molecule Drugs Using a Hierarchical Computational Procedure
Yassmine Chebaro et al.
JOURNAL OF PHYSICAL CHEMISTRY B (2012)
Multidimensional View of Amyloid Fibril Nucleation in Atomistic Detail
Fahimeh Baftizadeh et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2012)
A mutation in APP protects against Alzheimer's disease and age-related cognitive decline
Thorlakur Jonsson et al.
NATURE (2012)
Prion-like behaviour and tau-dependent cytotoxicity of pyroglutamylated amyloid-β
Justin M. Nussbaum et al.
NATURE (2012)
PEP-FOLD: an updated de novo structure prediction server for both linear and disulfide bonded cyclic peptides
Pierre Thevenet et al.
NUCLEIC ACIDS RESEARCH (2012)
Dimer Formation Enhances Structural Differences between Amyloid β-Protein (1-40) and (1-42): An Explicit-Solvent Molecular Dynamics Study
Bogdan Barz et al.
PLOS ONE (2012)
Atomic View of a Toxic Amyloid Small Oligomer
Arthur Laganowsky et al.
SCIENCE (2012)
Molecular Engineering of a Secreted, Highly Homogeneous, and Neurotoxic Aβ Dimer
Andreas Mueller-Schiffmann et al.
ACS CHEMICAL NEUROSCIENCE (2011)
Carbon Nanotube Inhibits the Formation of β-Sheet-Rich Oligomers of the Alzheimer's Amyloid-β(16-22) Peptide
Huiyu Li et al.
BIOPHYSICAL JOURNAL (2011)
Assessing the Quality of the OPEP Coarse-Grained Force Field
Alessandro Barducci et al.
JOURNAL OF CHEMICAL THEORY AND COMPUTATION (2011)
Distinct Morphologies for Amyloid Beta Protein Monomer: Aβ1-40, Aβ1-42, and Aβ1-40(D23N)
Sebastien Cote et al.
JOURNAL OF CHEMICAL THEORY AND COMPUTATION (2011)
Amyloid Fibrillation Kinetics: Insight from Atomistic Nucleation Theory
Raffaele Cabriolu et al.
JOURNAL OF MOLECULAR BIOLOGY (2011)
Ion Mobility Separation Coupled with MS Detects Two Structural States of Alzheimer's Disease Aβ1-40 Peptide Oligomers
Marcin Kloniecki et al.
JOURNAL OF MOLECULAR BIOLOGY (2011)
Characteristics of Amyloid-Related Oligomers Revealed by Crystal Structures of Macrocyclic β-Sheet Mimics
Cong Liu et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2011)
Effects of all-atom force fields on amyloid oligomerization: replica exchange molecular dynamics simulations of the A beta(16-22) dimer and trimer
Phuong H. Nguyen et al.
PHYSICAL CHEMISTRY CHEMICAL PHYSICS (2011)
Molecular basis for amyloid-β polymorphism
Jacques-Philippe Colletier et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2011)
How Fast-Folding Proteins Fold
Kresten Lindorff-Larsen et al.
SCIENCE (2011)
A Multiscale Approach to Characterize the Early Aggregation Steps of the Amyloid-Forming Peptide GNNQQNY from the Yeast Prion Sup-35
Jessica Nasica-Labouze et al.
PLOS COMPUTATIONAL BIOLOGY (2011)
Low molecular weight oligomers of amyloid peptides display β-barrel conformations: A replica exchange molecular dynamics study in explicit solvent
Alfonso De Simone et al.
JOURNAL OF CHEMICAL PHYSICS (2010)
Disordered versus Fibril-like Amyloid β (25-35) Dimers in Water: Structure and Thermodynamics
Madeleine Kittner et al.
JOURNAL OF PHYSICAL CHEMISTRY B (2010)
Elucidation of Amyloid β-Protein Oligomerization Mechanisms: Discrete Molecular Dynamics Study
B. Urbanc et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2010)
Amyloid Fibril Polymorphism Is under Kinetic Control
Riccardo Pellarin et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2010)
Factors Governing Fibrillogenesis of Polypeptide Chains Revealed by Lattice Models
Mai Suan Li et al.
PHYSICAL REVIEW LETTERS (2010)
Extending the PRIME model for protein aggregation to all 20 amino acids
Mookyung Cheon et al.
PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS (2010)
Induced β-Barrel Formation of the Alzheimer's Aβ25-35 Oligomers on Carbon Nanotube Surfaces: Implication for Amyloid Fibril Inhibition
Zhaoming Fu et al.
BIOPHYSICAL JOURNAL (2009)
MUPHY: A parallel MUlti PHYsics/scale code for high performance bio-fluidic simulations
M. Bernaschi et al.
COMPUTER PHYSICS COMMUNICATIONS (2009)
Effect of β-sheet propensity on peptide aggregation
Giovanni Bellesia et al.
JOURNAL OF CHEMICAL PHYSICS (2009)
Simulations of nucleation and elongation of amyloid fibrils
Jianing Zhang et al.
JOURNAL OF CHEMICAL PHYSICS (2009)
Striking Effects of Hydrodynamic Interactions on the Simulated Diffusion and Folding of Proteins
Tamara Frembgen-Kesner et al.
JOURNAL OF CHEMICAL THEORY AND COMPUTATION (2009)
Structures and Thermodynamics of Alzheimer's Amyloid-β Aβ(16-35) Monomer and Dimer by Replica Exchange Molecular Dynamics Simulations: Implication for Full-Length Aβ Fibrillation
Yassmine Chebaro et al.
JOURNAL OF PHYSICAL CHEMISTRY B (2009)
Amyloid-β protein oligomerization and the importance of tetramers and dodecamers in the aetiology of Alzheimer's disease
Summer L. Bernstein et al.
NATURE CHEMISTRY (2009)
PEP-FOLD: an online resource for de novo peptide structure prediction
Julien Maupetit et al.
NUCLEIC ACIDS RESEARCH (2009)
Structure-neurotoxicity relationships of amyloid β-protein oligomers
Kenjiro Ono et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)
Thermodynamics and dynamics of amyloid peptide oligomerization are sequence dependent
Yan Lu et al.
PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS (2009)
Targeting the early steps of A beta 16-22 protofibril disassembly by N-methylated inhibitors: A numerical study
Yassmine Chebaro et al.
PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS (2009)
A Recessive Mutation in the APP Gene with Dominant-Negative Effect on Amyloidogenesis
Giuseppe Di Fede et al.
SCIENCE (2009)
An Analytical Solution to the Kinetics of Breakable Filament Assembly
Tuomas P. J. Knowles et al.
SCIENCE (2009)
Quasihomogeneous nucleation of amyloid beta yields numerical bounds for the critical radius, the surface tension, and the free energy barrier for nucleus formation
K. Garai et al.
JOURNAL OF CHEMICAL PHYSICS (2008)
Self-assembly of the β2-microglobulin NHVTLSQ peptide using a coarse-grained protein model reveals β-barrel species
Wei Song et al.
JOURNAL OF PHYSICAL CHEMISTRY B (2008)
Formation and Growth of Oligomers: A Monte Carlo Study of an Amyloid Tau Fragment
Da-Wei Li et al.
PLOS COMPUTATIONAL BIOLOGY (2008)
Thermodynamics and kinetics of aggregation for the GNNQQNY peptide
Birgit Strodel et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2007)
Hydrophobic cooperativity as a mechanism for amyloid nucleation
Ronald D. Hills et al.
JOURNAL OF MOLECULAR BIOLOGY (2007)
Monomer adds to preformed structured oligomers of Aβ-peptides by a two-stage dock-lock mechanism
Phuong H. Nguyen et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2007)
Computational Simulations of the Early Steps of Protein Aggregation
Guanghong Wei et al.
PRION (2007)
Stability and structure of oligomers of the Alzheimer peptide Aβ16-22:: From the dimer to the 32-mer
Ute F. Rohrig et al.
BIOPHYSICAL JOURNAL (2006)
Impact of the mutation A21G (Flemish variant) on Alzheimer's β-amyloid dimers by molecular dynamics simulations
Alexis Huet et al.
BIOPHYSICAL JOURNAL (2006)
Structures of soluble amyloid oligomers from computer simulations
Adrien Melquiond et al.
PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS (2006)
Intersheet rearrangement of polypeptides during nucleation of β-sheet aggregates
SA Petty et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2005)
Structure of the cross-β spine of amyloid-like fibrils
R Nelson et al.
NATURE (2005)
In silico assembly of Alzheimer's Aβ16-22 peptide into β-sheets
S Santini et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2004)
Sampling the self-assembly pathways of KFFE hexamers
GH Wei et al.
BIOPHYSICAL JOURNAL (2004)
Pathway complexity of Alzheimer's β-amyloid Aβ16-22 peptide assembly
S Santini et al.
STRUCTURE (2004)
Sampling the complex energy landscape of a simple β-hairpin
GH Wei et al.
JOURNAL OF CHEMICAL PHYSICS (2003)
Identification and characterization of key kinetic intermediates in amyloid β-protein fibrillogenesis
MD Kirkitadze et al.
JOURNAL OF MOLECULAR BIOLOGY (2001)
Generating ensemble averages for small proteins from extended conformations by Monte Carlo simulations
P Derreumaux
PHYSICAL REVIEW LETTERS (2000)
分享论文
