相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。
Article
Biochemistry & Molecular Biology
SPOP mutations promote p62/SQSTM1-dependent autophagy and Nrf2 activation in prostate cancer
Qing Shi et al.
Summary: This study reveals that SPOP mutations induce non-degradative ubiquitination of p62, leading to suppression of p62-dependent autophagy and decreased Nrf2-mediated transcriptional activation of antioxidant genes, thus promoting tumor formation in SPOP-mutated PCa.
CELL DEATH AND DIFFERENTIATION (2022)