4.6 Editorial Material

On 'Deuterium exchange of poly-dl-alanine in aqueous solution' by Arieh Berger and K. Linderstrom-Lang

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ELSEVIER SCIENCE INC
DOI: 10.1016/j.abb.2022.109185

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Hydrogen exchange; NMR; HDX-MS; Protein dynamics; Protein stability

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This commentary highlights the landmark manuscript published in 1957 by Arieh Berger and K. Linderstrom-Lang that describes the measurement and analysis of hydrogen exchange rates. The manuscript, which has been widely referenced, is recognized for its significant impact on characterizing the structure and dynamics of natively folded proteins and folding intermediates.
This commentary highlights the landmark manuscript published in 1957 by Arieh Berger and K. Linderstrom-Lang that describes the measurement and analysis of hydrogen exchange rates. This highly referenced manuscript is recognized because the impact hydrogen exchange has had on characterizing the structure and dynamics of natively folded proteins and folding intermediates.

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