期刊
APPLIED SPECTROSCOPY REVIEWS
卷 58, 期 8, 页码 525-544出版社
TAYLOR & FRANCIS INC
DOI: 10.1080/05704928.2022.2052308
关键词
Synchrotron infrared; microspectroscopy; biomedicine
This article introduces the important role of synchrotron radiation-FTIR microspectroscopy in the field of biomedical research, with a focus on neurodegenerative diseases, diabetes, preeclampsia, and other relevant areas.
Human health is a subject matter that requires a multifold strategy starting by understanding the molecular basis of diseases, development of diagnostic approaches, and subsequently by finding possible innovative treatments. Neurodegenerative diseases, degenerative medicine, diabetes, preeclampsia, and pharmaceutics are just a few examples to mention. Therefore, the challenge for the scientific community is to develop new and creative means for acquiring, processing and interpreting the biomolecular information involved with tissues, single cells or cells in a microenvironment, at cellular and sub-cellular resolution. Synchrotron facilities open the door for a huge number of biological and biomedical applications, where high spatial resolution and high quality information are a must. This review highlights the strong role that the Synchrotron radiation-FTIR microspectroscopy (SR-mu FTIR) plays in various biomedical fields with a special focus on the above-mentioned cases.
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