期刊
ANNUAL REVIEW OF MICROBIOLOGY
卷 76, 期 -, 页码 435-460出版社
ANNUAL REVIEWS
DOI: 10.1146/annurev-micro-041020-022206
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资金
- US National Institutes of Health [R01 AI095706, P01 CA023766, U01 AI124275, R01 AI042135]
- Duchossois Family Institute of the University of Chicago
This study reviews recent research on the influence of the gut microbiota on human health and disease susceptibility and resistance. It discusses the association between gut microbiota and certain human diseases and highlights translational advances in using gut microbiota to treat diseases. The opportunities and challenges in translating microbiome research from and to the bedside are also discussed.
Extensive research has elucidated the influence of the gut microbiota on human health and disease susceptibility and resistance. We review recent clinical and laboratory-based experimental studies associating the gut microbiota with certain human diseases. We also highlight ongoing translational advances that manipulate the gut microbiota to treat human diseases and discuss opportunities and challenges in translating microbiome research from and to the bedside.
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