Comparison of Patients Infected With Delta Versus Omicron COVID-19 Variants Presenting to Paris Emergency Departments A Retrospective Cohort Study

Letter Medicine, General & Internal

Characteristics and Outcomes of Hospitalized Patients in South Africa During the COVID-19 Omicron Wave Compared With Previous Waves

Caroline Maslo et al.

JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION (2022)

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Editorial Material Medicine, General & Internal

Winter of Omicron-The Evolving COVID-19 Pandemic

Carlos del Rio et al.

JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION (2022)

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Article Virology

Characterization of the novel SARS-CoV-2 Omicron (B.1.1.529) variant of concern and its global perspective

Shailendra K. Saxena et al.

Summary: Omicron is the latest variant of concern of SARS-CoV-2, with more mutations compared to the previous Delta variant. Fifteen of these mutations are located in the receptor-binding domain of the spike glycoprotein, which may affect transmissibility, infectivity, antibody neutralization, and vaccine efficacy. The study provides insights into the mutational hotspots of Omicron and its global impact on transmission, testing, and immunity.

JOURNAL OF MEDICAL VIROLOGY (2022)

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Article Medicine, General & Internal

Early assessment of the clinical severity of the SARS-CoV-2 omicron variant in South Africa: a data linkage study

Nicole Wolter et al.

Summary: According to data analysis from South Africa, individuals infected with the omicron variant have a lower likelihood of hospitalization compared to those infected with non-omicron variants. Furthermore, individuals infected with the omicron variant have a lower odds of severe disease compared to individuals infected with the earlier delta variant.

LANCET (2022)

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Letter Medicine, General & Internal

Reduced neutralisation of SARS-CoV-2 omicron B.1.1.529 variant by post-immunisation serum

Wanwisa Dejnirattisai et al.

LANCET (2022)

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Article Multidisciplinary Sciences

Omicron extensively but incompletely escapes Pfizer BNT162b2 neutralization

Sandile Cele et al.

Summary: The study found that the Omicron variant has reduced neutralizing effectiveness in individuals vaccinated with Pfizer BNT162b2, but those who had previously been infected with SARS-CoV-2 showed better neutralization against Omicron.

NATURE (2022)

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Article Infectious Diseases

Decreased severity of disease during the first global omicron variant covid-19 outbreak in a large hospital in tshwane, south africa

F. Abdullah et al.

Summary: This study analyzed the clinical data of COVID-19 patients admitted to a hospital in Tshwane during the Omicron wave, and found that the severity of the disease was decreased compared to previous waves, with lower death rates and ICU admissions.

INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES (2022)

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Article Infectious Diseases

Outbreak caused by the SARS-CoV-2 Omicron variant in Norway, November to December 2021

Lin T. Brandal et al.

Summary: In the Omicron SARS-CoV-2 outbreak in Oslo, Norway, most infected individuals were aged 30-50, 96% were vaccinated, with an attack rate of 74%, but none required hospitalization.

EUROSURVEILLANCE (2021)

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Editorial Material Medicine, General & Internal

Omicron SARS-CoV-2 variant: a new chapter in the COVID-19 pandemic

Salim S. Abdool Karim et al.

LANCET (2021)

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Editorial Material Medicine, General & Internal

SARS-CoV-2 variants and ending the COVID-19 pandemic

Arnaud Fontanet et al.

LANCET (2021)

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Article Multidisciplinary Sciences

Possible future waves of SARS-CoV-2 infection generated by variants of concern with a range of characteristics

Louise Dyson et al.

Summary: The viral reproduction of SARS-CoV-2 provides opportunities for acquiring advantageous mutations, and different mathematical models show that the epidemiological trajectories of potential VOCs depend on their transmissibility and immune escape capability. Variants with transmission advantages or immune escape properties can generate waves of infections, while variants with lower transmissibility but partial immune escape may only be revealed after further relaxation of control measures.

NATURE COMMUNICATIONS (2021)

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News Item Medicine, General & Internal