期刊
ANNALS OF DIAGNOSTIC PATHOLOGY
卷 58, 期 -, 页码 -出版社
ELSEVIER SCIENCE INC
DOI: 10.1016/j.anndiagpath.2022.151906
关键词
Biphasic squamoid alveolar renal cell; carcinoma; Cytophagocytosis; Cyclin D1; Papillary renal cell carcinoma
类别
Biphasic squamoid alveolar renal cell carcinoma is a rare variant of papillary renal cell carcinoma with distinct histomorphology and immunophenotype. The cytomorphologic features of this type of carcinoma have not been described. This study correlates the cytologic features with histomorphology and immunophenotype, providing new insights into this disease.
Biphasic squamoid alveolar renal cell carcinoma is a newly described rare morphologic variant of papillary renal cell carcinoma. Its characteristic histomorphology and immunophenotype have been well described in the literature. Namely, BSARCC is composed of a dual-cell population with nests of larger squamoid cells surrounded by a single layer of cuboidal cells in alveolar arrangements. Invariably, the squamoid component expresses cyclin D1. More recently, MET alterations have been identified within a subset of BSARCC, raising the possibility for targeted MET inhibitor therapy. To the best of our knowledge the cytomorphologic features of BSARCC have yet to be described. Herein we correlate the cytologic features (percutaneous image-guided fine needle aspiration) of BSARCC to its corresponding histomorphology and immunophenotype (core needle biopsy).
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据