☆ 4.8 Article

Ternary Alloy PtWMn as a Mn Nanoreservoir for High-Field MRI Monitoring and Highly Selective Ferroptosis Therapy

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2022)

相关参考文献

注意：仅列出部分参考文献，下载原文获取全部文献信息。

Article Engineering, Biomedical

A tumor microenvironment responsive nanoplatform with oxidative stress amplification for effective MRI-based visual tumor ferroptosis

Shiwei Luo et al.

Summary: Ferroptosis is a promising non-apoptotic regulated cell death form for cancer treatment. However, the efficacy of ferroptosis is limited by high glutathione levels and insufficient hydrogen peroxide levels in tumors. In this study, a theranostic nanoplatform was designed to enhance ferroptosis in the tumor microenvironment by releasing active components, and it was also used for tumor-specific magnetic resonance imaging, exhibiting high specificity and efficacy.

ACTA BIOMATERIALIA (2022)

添加到收藏夹

Article Chemistry, Multidisciplinary

An Ultrahigh-Field-Tailored T1-T2 Dual-Mode MRI Contrast Agent for High-Performance Vascular Imaging

Jin Wang et al.

Summary: The article introduces a T-1-T-2 dual-mode contrast agent designed for ultrahigh-field MRI, which not only improves resolution and signal-to-noise ratio, but also effectively displays microvasculature structures with high sensitivity and accuracy in detecting tumor vascular permeability.

ADVANCED MATERIALS (2021)

添加到收藏夹

Article Chemistry, Multidisciplinary

Biodegradable Charge-Transfer Complexes for Glutathione Depletion Induced Ferroptosis and NIR-II Photoacoustic Imaging Guided Cancer Photothermal Therapy

Changjin Ou et al.

Summary: The development of novel NIR-II absorbing organic photothermal agents is crucial for enhancing phototherapeutic efficacy, and TMB-F4TCNQ, with higher charge transfer degree and strong NIR-II absorption ability, exhibits excellent photothermal effect with potential for precise and efficient photothermal therapy in vivo.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2021)

添加到收藏夹

Article Engineering, Biomedical

One Responsive Stone, Three Birds: Mn(III)-Hemoporfin Frameworks with Glutathione-Enhanced Degradation, MRI, and Sonodynamic Therapy

Peng Geng et al.

Summary: Mn(III)-HFs/PEG is a nanosonosensitizer that reacts with GSH to exhibit enhanced degradation, strong MRI capability, and improved O-1(2) generation ability under US irradiation. This nanomaterial not only significantly suppresses deep-seated tumors but also can be efficiently metabolized in vivo.

ADVANCED HEALTHCARE MATERIALS (2021)

添加到收藏夹

Article Chemistry, Multidisciplinary

Revealing the Viscosity Changes in Lipid Droplets during Ferroptosis by the Real-Time and In Situ Near-Infrared Imaging

Baoli Dong et al.

Summary: The study revealed the changes of lipid droplets viscosity during ferroptosis using a novel viscosity-sensitive near-infrared fluorescent probe. The experiment results showed a significant increase in lipid droplets viscosity during ferroptosis, while there was nearly no change in cells treated with ferroptosis inhibitors simultaneously.

ACS SENSORS (2021)

添加到收藏夹

Article Chemistry, Multidisciplinary

High-Performance Self-Cascade Pyrite Nanozymes for Apoptosis-Ferroptosis Synergistic Tumor Therapy

Xiangqin Meng et al.

Summary: The pyrite peroxidase nanozyme demonstrates ultra-high affinity for H2O2 and possesses intrinsic glutathione oxidase-like activity, resulting in abundant production of (OH)-O-center dot and depletion of reduced glutathione, inducing apoptosis and ferroptosis of tumor cells. It shows potential for effective therapeutic application in tumor catalytic therapy.

ACS NANO (2021)

添加到收藏夹

Article Chemistry, Multidisciplinary

An Acidity-Unlocked Magnetic Nanoplatform Enables Self-Boosting ROS Generation through Upregulation of Lactate for Imaging-Guided Highly Specific Chemodynamic Therapy

Linan Shi et al.

Summary: A novel nanoplatform was developed in this study, which can achieve high-efficient tumor-specific catalytic anticancer treatment in acidic tumor microenvironments through a cyclic amplification strategy, leading to enhanced Fenton-like reaction. Ultimately, this smart nanoplatform enables self-boosting generation of reactive oxygen species (ROS), inducing strong intracellular oxidative stress, and resulting in substantial anticancer outcomes in vivo.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2021)

添加到收藏夹

Article Chemistry, Multidisciplinary

NIR-Actuated Remote Activation of Ferroptosis in Target Tumor Cells through a Photothermally Responsive Iron-Chelated Biopolymer Nanoplatform

Chencheng Xue et al.

Summary: A polydopamine-based nanoplatform was developed for efficient loading of Fe2+ and beta-lapachone, which could trigger ferroptosis in tumor cells under near-infrared light. The platform could generate mild hyperthermia under NIR irritation, activate cellular heat shock response, and enhance intracellular H2O2 formation, promoting Fe2+-mediated lipid peroxidation and beta-lapachone release.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2021)

添加到收藏夹

Review Oncology

Broadening horizons: the role of ferroptosis in cancer

Xin Chen et al.

Summary: Ferroptosis is an iron-dependent form of regulated cell death driven by excessive lipid peroxidation, and can be induced by various agents to suppress tumor growth while also potentially triggering inflammation-associated immunosuppression. The extent of ferroptosis's impact on tumor biology and its interactions with other signaling pathways are still under investigation.

NATURE REVIEWS CLINICAL ONCOLOGY (2021)

添加到收藏夹

Article Multidisciplinary Sciences

Generation of hydroxyl radical-activatable ratiometric near-infrared bimodal probes for early monitoring of tumor response to therapy

Luyan Wu et al.

Summary: The response of tumors to radiotherapy or ferroptosis is closely linked to hydroxyl radical production, and accurate imaging of this reactive oxygen species may allow for monitoring of therapy response. A ratiometric probe has been developed for in vivo imaging of hydroxyl radical generation, providing a reliable method for monitoring treatment response in tumors undergoing erastin-induced ferroptosis or radiotherapy.

NATURE COMMUNICATIONS (2021)

添加到收藏夹

Article Multidisciplinary Sciences

Nanomedicine enables autophagy-enhanced cancer-cell ferroptosis

Jiacai Yang et al.

Summary: This study presents an intriguing nanomedicine strategy for achieving autophagy-enhanced ferroptosis in cancer therapy. The construction of trehalose-loaded mSiO(2)@MnOx-mPEG nanoparticles allowed for the induction of cancer-cell ferroptosis by deactivating GPX4 and subsequent autophagy by trehalose release, leading to a substantial antitumor effect in vitro and in vivo.

SCIENCE BULLETIN (2021)

添加到收藏夹

Article Chemistry, Multidisciplinary

Metabolic Control by Heat Stress Determining Cell Fate to Ferroptosis for Effective Cancer Therapy

Shaowei Xie et al.

Summary: The flexible manipulation of cancer cell fate through exogenous stimulation-induced metabolic reprogramming can effectively handle therapy resistance and sensitize tumors to ferroptosis. The proposed heat-triggered tumor-specific ferroptosis strategy utilizing nanoformulation showed promising antitumor effects by inducing oxidative damage and targeting key pro-ferroptotic factors. This work provides insights and strategies for heat-triggered ferroptosis in situ, offering a potential alternative to direct ferroptosis inducers with reduced side effects.

ACS NANO (2021)

添加到收藏夹

Article Chemistry, Multidisciplinary

Single-Atom Pd Nanozyme for Ferroptosis-Boosted Mild-Temperature Photothermal Therapy

Mengyu Chang et al.

Summary: Photothermal therapy (PTT) is a promising tumor therapeutic modality, but minimizing damage to healthy tissues while maximizing efficiency is crucial. Utilizing a single-atom nanozyme (SAzyme) can improve the effectiveness of mild PTT by promoting ferroptosis.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2021)

添加到收藏夹

Article Chemistry, Multidisciplinary

A Polarity-Sensitive Ratiometric Fluorescence Probe for Monitoring Changes in Lipid Droplets and Nucleus during Ferroptosis

Kang-Nan Wang et al.

Summary: This study introduces the first LD/nucleus dual-targeted ratiometric fluorescent probe, CQPP, to monitor polarity changes in the cellular microenvironment. Through the application of CQPP, it was found that LD polarity increased in the ferroptosis model, while the polarity between LDs and cytoplasm homogenized.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2021)

添加到收藏夹

Article Multidisciplinary Sciences

Artificially engineered antiferromagnetic nanoprobes for ultra-sensitive histopathological level magnetic resonance imaging

Zeyu Liang et al.

Summary: The study successfully developed an ultra-sensitive antiferromagnetic nanoparticle probe for use in ultra-high-field (UHF) magnetic resonance imaging by rationally engineering the size, spin alignment, and magnetic moment of the nanoparticles. This probe enables sensitive detection of small primary tumors and micrometastases in mice, with sensitivity and accuracy comparable to histopathological examination.

NATURE COMMUNICATIONS (2021)

添加到收藏夹

Article Multidisciplinary Sciences

A nonferrous ferroptosis-like strategy for antioxidant inhibition-synergized nanocatalytic tumor therapeutics

Chenyao Wu et al.

Summary: This study introduces a non-ferrous ferroptosis-like strategy based on a hybrid CoMoO4-phosphomolybdic acid nanosheet (CPMNS), which achieves efficient anticancer efficacy through specific mechanisms. The high feasibility of this approach in nanocatalytic medicine is expected to advance cancer therapeutic regimens in the future.

SCIENCE ADVANCES (2021)

添加到收藏夹

Article Medicine, Research & Experimental

Manganese porphyrin-based metal-organic framework for synergistic sonodynamic therapy and ferroptosis in hypoxic tumors

Qingbo Xu et al.

Summary: The manganese porphyrin-based metal-organic framework (Mn-MOF) demonstrates great potential in enhancing cancer therapy through sonodynamic therapy and ferroptosis, showing strong anticancer activity and antitumor immunity in hypoxic tumors.

THERANOSTICS (2021)

添加到收藏夹

Article Biochemistry & Molecular Biology

Cobalt nanoparticles trigger ferroptosis-like cell death (oxytosis) in neuronal cells: Potential implications for neurodegenerative disease

Govind Gupta et al.

FASEB JOURNAL (2020)

添加到收藏夹

Article Chemistry, Analytical

Manganese ion chelated FeOCl@PB@PDA@BPQDs nanocomposites as a tumor microenvironment-mediated nanoplatform for enhanced tumor imaging and therapy

Ming Zhang et al.

SENSORS AND ACTUATORS B-CHEMICAL (2020)

添加到收藏夹

Article Chemistry, Multidisciplinary

Enhanced Ferroptosis by Oxygen-Boosted Phototherapy Based on a 2-in-1 Nanoplatform of Ferrous Hemoglobin for Tumor Synergistic Therapy

Tian Xu et al.

ACS NANO (2020)

添加到收藏夹

Editorial Material Biochemistry & Molecular Biology

SnapShot: Ferroptosis

Kamyar Hadian et al.

CELL (2020)

添加到收藏夹

Article Chemistry, Multidisciplinary

Platelet Membrane-Camouflaged Magnetic Nanoparticles for Ferroptosis-Enhanced Cancer Immunotherapy

Qin Jiang et al.

SMALL (2020)

添加到收藏夹

Article Multidisciplinary Sciences

Tumor microenvironment-activatable Fe-doxorubicin preloaded amorphous CaCO3 nanoformulation triggers ferroptosis in target tumor cells

Chen-Cheng Xue et al.

SCIENCE ADVANCES (2020)

添加到收藏夹

Article Chemistry, Multidisciplinary

3-Bromopyruvate-Conjugated Nanoplatform-Induced Pro-Death Autophagy for Enhanced Photodynamic Therapy against Hypoxic Tumor

Yongyan Deng et al.

ACS NANO (2020)

添加到收藏夹

Article Chemistry, Multidisciplinary

Tumor-Targeted Cascade Nanoreactor Based on Metal-Organic Frameworks for Synergistic Ferroptosis-Starvation Anticancer Therapy

Xiuyan Wan et al.

ACS NANO (2020)

添加到收藏夹

Article Chemistry, Multidisciplinary

MnOxNanospikes as Nanoadjuvants and Immunogenic Cell Death Drugs with Enhanced Antitumor Immunity and Antimetastatic Effect

Binbin Ding et al.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2020)

添加到收藏夹

Article Chemistry, Inorganic & Nuclear

Reversible FRET Fluorescent Probe for Ratiometric Tracking of Endogenous Fe3+ in Ferroptosis

Jing Gao et al.

INORGANIC CHEMISTRY (2020)

添加到收藏夹

Article Chemistry, Multidisciplinary

Light-free Generation of Singlet Oxygen through Manganese-Thiophene Nanosystems for pH-Responsive Chemiluminescence Imaging and Tumor Therapy

Chang Lu et al.

CHEM (2020)

添加到收藏夹

Article Multidisciplinary Sciences

Magnetic field boosted ferroptosis-like cell death and responsive MRI using hybrid vesicles for cancer immunotherapy

Bo Yu et al.

NATURE COMMUNICATIONS (2020)

添加到收藏夹

Article Multidisciplinary Sciences

Vacancies on 2D transition metal dichalcogenides elicit ferroptotic cell death

Shujuan Xu et al.

NATURE COMMUNICATIONS (2020)

添加到收藏夹

Article Chemistry, Multidisciplinary

Self-Amplification of Tumor Oxidative Stress with Degradable Metallic Complexes for Synergistic Cascade Tumor Therapy

Gui Chen et al.

NANO LETTERS (2020)

添加到收藏夹

Article Engineering, Biomedical

Ultrasmall Ternary FePtMn Nanocrystals with Acidity-Triggered Dual-Ions Release and Hypoxia Relief for Multimodal Synergistic Chemodynamic/Photodynamic/Photothermal Cancer Therapy

Baochan Yang et al.

ADVANCED HEALTHCARE MATERIALS (2020)

添加到收藏夹

Article Chemistry, Multidisciplinary

Reactivity-Based Probe of the Iron(II)-Dependent Interactome Identifies New Cellular Modulators of Ferroptosis

Ying-Chu Chen et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2020)

添加到收藏夹

Article Chemistry, Physical

Bimetallic Pt3Mn nanowire network structures with enhanced electrocatalytic performance for methanol oxidation

Kai Peng et al.

INTERNATIONAL JOURNAL OF HYDROGEN ENERGY (2020)

添加到收藏夹

Article Chemistry, Multidisciplinary

Targeted GSH-exhausting and hydroxyl radical self-producing manganese-silica nanomissiles for MRI guided ferroptotic cancer therapy

Weidong Fei et al.

NANOSCALE (2020)

添加到收藏夹

Article Biochemistry & Molecular Biology

Organelle-specific analysis of labile Fe(II) during ferroptosis by using a cocktail of various colour organelle-targeted fluorescent probes

Tasuku Hirayama et al.

METALLOMICS (2019)

添加到收藏夹

Article Chemistry, Physical

Generalized Synthesis of Uniform Metal Nanoparticles Assisted with Tungsten Hexacarbonyl

Xixia Zhao et al.

CHEMISTRY OF MATERIALS (2019)

添加到收藏夹

Article Chemistry, Multidisciplinary

A Mn(III)-Sealed Metal-Organic Framework Nanosystem for Redox-Unlocked Tumor Theranostics

Shuang-Shuang Wan et al.

ACS NANO (2019)

添加到收藏夹

Article Chemistry, Multidisciplinary

Coordinatively Unsaturated Fe3+ Based Activatable Probes for Enhanced MRI and Therapy of Tumors

Peisen Zhang et al.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2019)

添加到收藏夹

Review Oncology

Targeting Ferroptosis to Iron Out Cancer

Behrouz Hassannia et al.

CANCER CELL (2019)

添加到收藏夹

Article Chemistry, Analytical

Recombinant Fusion Streptavidin as a Scaffold for DNA Nanotetrads for Nucleic Acid Delivery and Telomerase Activity Imaging in Living Cells

Zhi-Mei Huang et al.

ANALYTICAL CHEMISTRY (2019)

添加到收藏夹

Article Chemistry, Multidisciplinary

Synthesis of Copper Peroxide Nanodots for H2O2 Self-Supplying Chemodynamic Therapy

Li-Sen Lin et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2019)

添加到收藏夹

Article Nanoscience & Nanotechnology

FePt@MnO-Based Nanotheranostic Platform with Acidity-Triggered Dual-Ions Release for Enhanced MR Imaging-Guided Ferroptosis Chemodynamic Therapy

Baochan Yang et al.

ACS APPLIED MATERIALS & INTERFACES (2019)

添加到收藏夹

Article Chemistry, Multidisciplinary

Enhanced Antitumor Efficacy by a Cascade of Reactive Oxygen Species Generation and Drug Release

Sheng Wang et al.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2019)

添加到收藏夹

Article Chemistry, Multidisciplinary

Nanolongan with Multiple On-Demand Conversions for Ferroptosis-Apoptosis Combined Anticancer Therapy

Weier Bao et al.

ACS NANO (2019)

添加到收藏夹

Review Chemistry, Multidisciplinary

Structure-Relaxivity Relationships of Magnetic Nanoparticles for Magnetic Resonance Imaging

Zijian Zhou et al.

ADVANCED MATERIALS (2019)

添加到收藏夹

Review Chemistry, Multidisciplinary

Chemistry of MRI Contrast Agents: Current Challenges and New Frontiers

Jessica Wahsner et al.

CHEMICAL REVIEWS (2019)

添加到收藏夹

Article Chemistry, Multidisciplinary

Self-Assembled Copper Amino Acid Nanoparticles for in Situ Glutathione AND H2O2 Sequentially Triggered Chemodynamic Therapy

Baojin Ma et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2019)

添加到收藏夹

Article Pharmacology & Pharmacy

Dual GSH-exhausting sorafenib loaded manganese-silica nanodrugs for inducing the ferroptosis of hepatocellular carcinoma cells

Hongxia Tang et al.

INTERNATIONAL JOURNAL OF PHARMACEUTICS (2019)

添加到收藏夹

Article Nanoscience & Nanotechnology

A piezoelectric, strain-controlled antiferromagnetic memory insensitive to magnetic fields

Han Yan et al.

NATURE NANOTECHNOLOGY (2019)

添加到收藏夹

Article Chemistry, Physical

Implanting Mo Atoms into Surface Lattice of Pt3Mn Alloys Enclosed by High-Indexed Facets: Promoting Highly Active Sites for Ethylene Glycol Oxidation

Yao Wang et al.

ACS CATALYSIS (2019)

添加到收藏夹

Review Oncology

Ferroptosis at the crossroads of cancer-acquired drug resistance and immune evasion

Jose Pedro Friedmann Angeli et al.

NATURE REVIEWS CANCER (2019)

添加到收藏夹

Article Chemistry, Multidisciplinary

Quantitative Profiling of Protein Carbonylations in Ferroptosis by an Aniline-Derived Probe

Ying Chen et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2018)

添加到收藏夹

Article Chemistry, Multidisciplinary

Rationally Designed Fluorescence (OH)-O-center dot Probe with High Sensitivity and Selectivity for Monitoring the Generation of (OH)-O-center dot in Iron Autoxidation without Addition of H2O2

Hongyu Li et al.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2018)

添加到收藏夹

Article Chemistry, Multidisciplinary

Fenton-Reaction-Acceleratable Magnetic Nanoparticles for Ferroptosis Therapy of Orthotopic Brain Tumors

Zheyu Shen et al.

ACS NANO (2018)

添加到收藏夹

Article Chemistry, Multidisciplinary

Arginine-Rich Manganese Silicate Nanobubbles as a Ferroptosis-Inducing Agent for Tumor-Targeted Theranostics

Shuaifei Wang et al.

ACS NANO (2018)

添加到收藏夹

Article Chemistry, Multidisciplinary

Ferrous-Supply-Regeneration Nanoengineering for Cancer-Cell-Specific Ferroptosis in Combination with Imaging-Guided Photodynamic Therapy

Tao Liu et al.

ACS NANO (2018)

添加到收藏夹

Article Chemistry, Multidisciplinary

Changes in Catalytic and Adsorptive Properties of 2 nm Pt3Mn Nanoparticles by Subsurface Atoms

Zhenwei Wu et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2018)

添加到收藏夹

Article Chemistry, Multidisciplinary

Synthesis of Iron Nanometallic Glasses and Their Application in Cancer Therapy by a Localized Fenton Reaction

Chen Zhang et al.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2016)

添加到收藏夹

Article Chemistry, Multidisciplinary

A Janus Chelator Enables Biochemically Responsive MRI Contrast with Exceptional Dynamic Range

Eric M. Gale et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2016)

添加到收藏夹

Article Chemistry, Physical

Magnetization switching by spin-orbit torque in an antiferromagnet-ferromagnet bilayer system

Shunsuke Fukami et al.

NATURE MATERIALS (2016)

添加到收藏夹

Review Radiology, Nuclear Medicine & Medical Imaging

MRI at 7 Tesla and Above: Demonstrated and Potential Capabilities

Oliver Kraff et al.

JOURNAL OF MAGNETIC RESONANCE IMAGING (2015)

添加到收藏夹

Article Physics, Multidisciplinary

Spin Hall Effects in Metallic Antiferromagnets

Wei Zhang et al.

PHYSICAL REVIEW LETTERS (2014)

添加到收藏夹

Article Chemistry, Multidisciplinary

A Synergistically Enhanced T1-T2 Dual-Modal Contrast Agent

Zijian Zhou et al.

ADVANCED MATERIALS (2012)

添加到收藏夹

Editorial Material Chemistry, Multidisciplinary

Introduction to Concepts and Strategies for Molecular Imaging

Samuel Achilefu

CHEMICAL REVIEWS (2010)

添加到收藏夹

Article Chemistry, Multidisciplinary

A General Strategy for Preparation of Pt 3d-Transition Metal (Co, Fe, Ni) Nanocubes

Jun Zhang et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2009)

添加到收藏夹

© Peeref 2019-2024. All rights reserved.