Delayed ejaculation in men with depressive disorders

Delayed ejaculation belongs to the group of sexual disorders in men. The causes of delayed ejaculation or anejaculation are not exactly known. It is assumed that it can be caused by psychogenic or organic influences or their combinations. One of the causes of delayed ejaculation may be elevated prolactin levels, which may be increased by psychosocial stress, pituitary disorders or also treatment with selective serotonin reuptake inhibitors in the treatment of depression. We tested a selected group of 50 men who were diagnosed with a depressive disorder and whose antidepressant treatment lasted for at least 24 weeks. These patients reported long-term delayed ejaculation or, in some cases, anejaculation as comorbidity. The results showed significant Spearman's correlation between elevated prolactin levels and intravaginal ejaculation latency values (R = 0.45), as well as between Beck's Depression-II inventory and intravaginal ejaculation latency and latency values (R = 0.48).

Automated summary

Delayed ejaculation is a sexual disorder in men with causes that could be psychological, organic, or a combination of both. Elevated prolactin levels may contribute to this condition and can be caused by psychosocial stress, pituitary disorders, or treatment with selective serotonin reuptake inhibitors. This study found a significant correlation between elevated prolactin levels and delayed ejaculation, as well as a correlation between depression and delayed ejaculation.