Selective and Rapid Detection of Thiophenol by a Novel Fluorescent Probe with Cellular Imaging

Among sulfur-containing species, thiophenol (PhSH) is highly toxic but is uncommonly studied. Here a novel probe is reported for thiophenol with rapid response and high selectivity. Thiophenol was easily distinguished by this probe from other sulfur-containing species including anions and biothiols. The probe was employed for the determination of thiophenol in several buffer systems and in living cells, demonstrating suitability for future work.

Automated summary

A novel probe with rapid response and high selectivity for thiophenol has been reported, enabling easy differentiation of thiophenol from other sulfur-containing species. The probe has been successfully used for the determination of thiophenol in various buffer systems and living cells, showing great potential for future applications.