4.6 Article

CRTH2 Mediates Profibrotic Macrophage Differentiation and Promotes Lung Fibrosis

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Article Medicine, Research & Experimental

The lung microenvironment shapes a dysfunctiona response of alveolar macrophages in aging

Alexandra C. McQuattie-Pimentel et al.

Summary: This study identified homogeneous age-related changes in the transcriptome of alveolar macrophages and demonstrated that the lung microenvironment affects the proliferation capacity of these cells, which in turn impacts the resistance of older patients to influenza viral infection. Targeting strategies towards the aging lung microenvironment may be necessary to restore alveolar macrophage function in aging individuals.

JOURNAL OF CLINICAL INVESTIGATION (2021)

Article Respiratory System

CX3CR1-fractalkine axis drives kinetic changes of monocytes in fibrotic interstitial lung diseases

Flavia R. Greiffo et al.

EUROPEAN RESPIRATORY JOURNAL (2020)

Editorial Material Physiology

The Idiopathic Pulmonary Fibrosis Cell Atlas

Nir Neumark et al.

AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY (2020)

Article Biochemistry & Molecular Biology

Deficiency of CRTH2, a Prostaglandin D2 Receptor, Aggravates Bleomycin-induced Pulmonary Inflammation and Fibrosis

Soichiro Ueda et al.

AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY (2019)

Review Pharmacology & Pharmacy

Efficacy and Safety of Nintedanib for the Treatment of Idiopathic Pulmonary Fibrosis: An Update

Jose Antonio Rodriguez-Portal

DRUGS IN R&D (2018)

Article Immunology

Inhibition of CRTH2-mediated Th2 activation attenuates pulmonary hypertension in mice

Guilin Chen et al.

JOURNAL OF EXPERIMENTAL MEDICINE (2018)

Article Immunology

Monocyte-derived alveolar macrophages drive lung fibrosis and persist in the lung over the life span

Alexander V. Misharin et al.

JOURNAL OF EXPERIMENTAL MEDICINE (2017)

Article Urology & Nephrology

Breast Regression Protein-39/Chitinase 3-Like 1 Promotes Renal Fibrosis after Kidney Injury via Activation of Myofibroblasts

Tinika A. Montgomery et al.

JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY (2017)

Review Respiratory System

Pharmacological management of IPF

Raphael Borie et al.

RESPIROLOGY (2016)

Article Medicine, Research & Experimental

Chitinase 3-like-1 and its receptors in Hermansky-Pudlak syndrome-associated lung disease

Yang Zhou et al.

JOURNAL OF CLINICAL INVESTIGATION (2015)

Editorial Material Medicine, General & Internal

Forced Vital Capacity in Idiopathic Pulmonary Fibrosis - FDA Review of Pirfenidone and Nintedanib

Banu A. Karimi-Shah et al.

NEW ENGLAND JOURNAL OF MEDICINE (2015)

Article Medicine, General & Internal

A Phase 3 Trial of Pirfenidone in Patients with Idiopathic Pulmonary Fibrosis

Talmadge E. King et al.

NEW ENGLAND JOURNAL OF MEDICINE (2014)

Article Medicine, General & Internal

Efficacy and Safety of Nintedanib in Idiopathic Pulmonary Fibrosis

Luca Richeldi et al.

NEW ENGLAND JOURNAL OF MEDICINE (2014)

Review Biochemistry & Molecular Biology

Animal Models of Fibrotic Lung Disease

Bethany B. Moore et al.

AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY (2013)

Article Urology & Nephrology

PGD2-CRTH2 Pathway Promotes Tubulointerstitial Fibrosis

Hideyuki Ito et al.

JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY (2012)

Review Cell Biology

Molecular and cellular mechanisms of pulmonary fibrosis

Nevins W. Todd et al.

FIBROGENESIS & TISSUE REPAIR (2012)

Article Critical Care Medicine

Ly6Chi Monocytes Direct Alternatively Activated Profibrotic Macrophage Regulation of Lung Fibrosis

Michael A. Gibbons et al.

AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE (2011)

Article Critical Care Medicine

An Official ATS/ERSARS/ALAT Statement: Idiopathic Pulmonary Fibrosis: Evidence-based Guidelines for Diagnosis and Management

Ganesh Raghu et al.

AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE (2011)

Review Physiology

Role of Chitin and Chitinase/Chitinase-Like Proteins in Inflammation, Tissue Remodeling, and Injury

Chun Geun Lee et al.

ANNUAL REVIEW OF PHYSIOLOGY, VOL 73 (2011)

Article Biochemistry & Molecular Biology

TGF-beta driven lung fibrosis is macrophage dependent and blocked by Serum amyloid P

Lynne A. Murray et al.

INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY (2011)

Article Cardiac & Cardiovascular Systems

Serum and BALF YKL-40 levels are predictors of survival in idiopathic pulmonary fibrosis

Nicoline M. Korthagen et al.

RESPIRATORY MEDICINE (2011)

Article Critical Care Medicine

The Chitinase-like Proteins Breast Regression Protein-39 and YKL-40 Regulate Hyperoxia-induced Acute Lung Injury

Myung Hyun Sohn et al.

AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE (2010)

Review Allergy

Role of breast regression protein-39/YKL-40 in asthma and allergic responses

Chun Geun Lee et al.

ALLERGY ASTHMA & IMMUNOLOGY RESEARCH (2010)

Article Critical Care Medicine

Incidence and prevalence of idiopathic pulmonary fibrosis

Ganesh Raghu et al.

AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE (2006)

Article Medicine, General & Internal

The clinical course of patients with idiopathic pulmonary fibrosis

FJ Martinez et al.

ANNALS OF INTERNAL MEDICINE (2005)

Article Pharmacology & Pharmacy

Prostaglandin D2-induced eosinophilic airway inflammation is mediated by CRTH2 receptor

Y Shiraishi et al.

JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2005)

Article Immunology

Protection from pulmonary fibrosis in the absence of CCR2 signaling

BB Moore et al.

JOURNAL OF IMMUNOLOGY (2001)

Article Critical Care Medicine

Predicting survival in idiopathic pulmonary fibrosis: Scoring system and survival model

TE King et al.

AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE (2001)