Risk Factors Associated With Intraocular Lens Decentration After Cataract Surgery

center dot PURPOSE: To identify risk factors associated with in-traocular lens (IOL) decentration after uneventful pha-coemulsification with IOL implantation. center dot DESIGN: A prospective cohort study. center dot METHODS: All patients underwent a general ophthal-mologic examination. One month postoperatively, the magnitude and orientation of IOL decentration relative to the visual axis center were assessed using an OPD-Scan III aberrometer, and the vertical and horizontal decentra-tion values were determined. Univariate and multivariate linear regression analyses were performed to evaluate the association between the IOL decentration and ocular bio-metric parameters. center dot RESULTS: In total, 143 eyes of 143 patients were en-rolled. The mean decentration magnitude was 0.27 +/- 0.15 mm, and the decentration axis appeared at any orien-tation, with no orientation tendency. The horizontal and vertical decentration were -0.02 +/- 0.22 mm and 0.01 +/- 0.22 mm, respectively. Multivariate regression analy-sis showed that the white-to-white distance and the mag-nitude of angle alpha were positively associated with the de-centration magnitude ( P < .001, adj. R 2 = 0.121), the horizontal angle K and horizontal angle alpha were positively associated with the horizontal decentration ( P < .001, adj. R 2 = 0.209), and the anterior chamber depth and vertical angle K were positively associated with the verti-cal decentration ( P < .001, adj. R 2 = 0.152). center dot CONCLUSIONS: The IOL decentration magnitude was greater in patients with a larger white-to-white distance and a larger angle alpha, the horizontal decentration was greater in patients with a larger horizontal angle K and a larger horizontal angle alpha, and the vertical decentration was greater in patients with a deeper anterior chamber depth and a larger vertical angle K. In these patients, premium IOLs should be implanted cautiously. (Am JOphthalmol 2022;242: 88-95. (c) 2022 Elsevier Inc. All rights reserved.)

Automated summary

The purpose of this study was to identify risk factors associated with intraocular lens (IOL) decentration after uneventful phacoemulsification with IOL implantation. A cohort study was conducted, and a total of 143 eyes of 143 patients were enrolled. The study found that the magnitude of IOL decentration was greater in patients with a larger white-to-white distance and a larger angle alpha. The horizontal and vertical decentration were associated with horizontal angle K, horizontal angle alpha, anterior chamber depth, and vertical angle K. The study suggests that caution should be taken when implanting premium IOLs in these patients.