相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。LGALS3 (galectin 3) mediates an unconventional secretion of SNCA/α-synuclein in response to lysosomal membrane damage by the autophagic-lysosomal pathway in human midbrain dopamine neurons
Kevin Burbidge et al.
AUTOPHAGY (2022)
Alpha-Synuclein defects autophagy by impairing SNAP29-mediated autophagosome-lysosome fusion
Qilin Tang et al.
CELL DEATH & DISEASE (2021)
Nucleolipid Acid-Based Nanocarriers Restore Neuronal Lysosomal Acidification Defects
Mathias Brouillard et al.
FRONTIERS IN CHEMISTRY (2021)
PLGA-Based Nanoparticles for Neuroprotective Drug Delivery in Neurodegenerative Diseases
Anthony Cunha et al.
PHARMACEUTICS (2021)
ATP13A2 deficiency disrupts lysosomal polyamine export
Sarah van Veen et al.
NATURE (2020)
Identification of distinct pathological signatures induced by patient-derived α-synuclein structures in nonhuman primates
M. Bourdenx et al.
SCIENCE ADVANCES (2020)
The emerging roles of vacuolar-type ATPase-dependent Lysosomal acidification in neurodegenerative diseases
Qiaoyun Song et al.
TRANSLATIONAL NEURODEGENERATION (2020)
Synucleinopathy alters nanoscale organization and diffusion in the brain extracellular space through hyaluronan remodeling
Federico N. Soria et al.
NATURE COMMUNICATIONS (2020)
α-Synuclein Overexpression Induces Lysosomal Dysfunction and Autophagy Impairment in Human Neuroblastoma SH-SY5Y
Ana Carolina Nascimento et al.
NEUROCHEMICAL RESEARCH (2020)
Ubiquilins regulate autophagic flux through mTOR signalling and lysosomal acidification
Mumine Senturk et al.
NATURE CELL BIOLOGY (2019)
Autophagy in Synucleinopathy: The Overwhelmed and Defective Machinery
Marie-Laure Arotcarena et al.
CELLS (2019)
Oxidative stress in the aging substantia nigra and the etiology of Parkinson's disease
Benjamin G. Trist et al.
AGING CELL (2019)
A pH-responsive nanoparticle targets the neurokinin 1 receptor in endosomes to prevent chronic pain
Paulina D. Ramirez-Garcia et al.
NATURE NANOTECHNOLOGY (2019)
Lysosomal Dysfunction at the Centre of Parkinson's Disease and Frontotemporal Dementia/Amyotrophic Lateral Sclerosis
Rebecca L. Wallings et al.
TRENDS IN NEUROSCIENCES (2019)
Graphene quantum dots prevent α-synucleinopathy in Parkinson's disease
Donghoon Kim et al.
NATURE NANOTECHNOLOGY (2018)
Harnessing Lysosomal pH through PLGA Nanoemulsion as a Treatment of Lysosomal-Related Neurodegenerative Diseases
Geoffrey Prevot et al.
BIOCONJUGATE CHEMISTRY (2018)
Epidemiology of Parkinson's disease
Ole-Bjorn Tysnes et al.
JOURNAL OF NEURAL TRANSMISSION (2017)
α-Synuclein promotes dilation of the exocytotic fusion pore
Todd Logan et al.
NATURE NEUROSCIENCE (2017)
Misrouting of v-ATPase subunit V0a1 dysregulates lysosomal acidification in a neurodegenerative lysosomal storage disease model
Maria B. Bagh et al.
NATURE COMMUNICATIONS (2017)
Brain Disorders Due to Lysosomal Dysfunction
Alessandro Fraldi et al.
ANNUAL REVIEW OF NEUROSCIENCE, VOL 39 (2016)
Nanoparticles restore lysosomal acidification defects: Implications for Parkinson and other lysosomal-related diseases
Mathieu Bourdenx et al.
AUTOPHAGY (2016)
The position of lysosomes within the cell determines their luminal pH
Danielle E. Johnson et al.
JOURNAL OF CELL BIOLOGY (2016)
Innovative molecular-based fluorescent nanoparticles for multicolor single particle tracking in cells
Jonathan Daniel et al.
JOURNAL OF PHYSICS D-APPLIED PHYSICS (2016)
Targeting α-Synuclein: Therapeutic Options
Benjamin Dehay et al.
MOVEMENT DISORDERS (2016)
Lysosomal Re-acidification Prevents Lysosphingolipid-Induced Lysosomal Impairment and Cellular Toxicity
Christopher J. Folts et al.
PLOS BIOLOGY (2016)
Sensitive detection of lysosomal membrane permeabilization by lysosomal galectin puncta assay
Sonja Aits et al.
AUTOPHAGY (2015)
Targeting α-synuclein for treatment of Parkinson's disease: mechanistic and therapeutic considerations
Benjamin Dehay et al.
LANCET NEUROLOGY (2015)
Proteostasis and aging
Susmita Kaushik et al.
NATURE MEDICINE (2015)
Presenilin 1 Maintains Lysosomal Ca2+ Homeostasis via TRPML1 by Regulating vATPase-Mediated Lysosome Acidification
Ju-Hyun Lee et al.
CELL REPORTS (2015)
Lewy body extracts from Parkinson disease brains trigger α-synuclein pathology and neurodegeneration in mice and monkeys
Ariadna Recasens et al.
ANNALS OF NEUROLOGY (2014)
Single-Walled Carbon Nanotubes Alleviate Autophagic/Lysosomal Defects in Primary Glia from a Mouse Model of Alzheimer's Disease
Xue Xue et al.
NANO LETTERS (2014)
Lysosomal impairment in Parkinson's disease
Benjamin Dehay et al.
MOVEMENT DISORDERS (2013)
Self-propagation of pathogenic protein aggregates in neurodegenerative diseases
Mathias Jucker et al.
NATURE (2013)
The role of autophagy in neurodegenerative disease
Ralph A. Nixon
NATURE MEDICINE (2013)
Measurement of autophagy flux in the nervous system in vivo
K. Castillo et al.
CELL DEATH & DISEASE (2013)
Fiji: an open-source platform for biological-image analysis
Johannes Schindelin et al.
NATURE METHODS (2012)
Acidic Nanoparticles Are Trafficked to Lysosomes and Restore an Acidic Lysosomal pH and Degradative Function to Compromised ARPE-19 Cells
Gabriel C. Baltazar et al.
PLOS ONE (2012)
Loss of P-type ATPase ATP13A2/PARK9 function induces general lysosomal deficiency and leads to Parkinson disease neurodegeneration
Benjamin Dehay et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2012)
Pathological α-Synuclein Transmission Initiates Parkinson-like Neurodegeneration in Nontransgenic Mice
Kelvin C. Luk et al.
SCIENCE (2012)
Lysosomal positioning coordinates cellular nutrient responses
Viktor I. Korolchuk et al.
NATURE CELL BIOLOGY (2011)
A photoconvertible fluorescent reporter to track chaperone-mediated autophagy
Hiroshi Koga et al.
NATURE COMMUNICATIONS (2011)
α-Synuclein overexpression increases dopamine toxicity in BE(2)-M17 cells
Marco Bisaglia et al.
BMC NEUROSCIENCE (2010)
Endocytosis of nanomedicines
Gaurav Sahay et al.
JOURNAL OF CONTROLLED RELEASE (2010)
Regulation of Neuronal Survival Factor MEF2D by Chaperone-Mediated Autophagy
Qian Yang et al.
SCIENCE (2009)
Wild type α-synuclein is degraded by chaperone-mediated autophagy and macroautophagy in neuronal cells
Tereza Vogiatzi et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2008)
Lysosomal membrane permeabilization in cell death
P. Boya et al.
ONCOGENE (2008)
A guided tour into subcellular colocalization analysis in light microscopy
S. Bolte et al.
JOURNAL OF MICROSCOPY (2006)
α-Synuclein phosphorylation controls neurotoxicity and inclusion formation in a Drosophila model of Parkinson disease
L Chen et al.
NATURE NEUROSCIENCE (2005)
Impaired degradation of mutant α-synuclein by chaperone-mediated autophagy
AM Cuervo et al.
SCIENCE (2004)
α-synuclein is degraded by both autophagy and the proteasome
JL Webb et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
Co-ordinate transcriptional regulation of dopamine synthesis genes by α-synuclein in human neuroblastoma cell lines
MJ Baptista et al.
JOURNAL OF NEUROCHEMISTRY (2003)
α-Synuclein is phosphorylated in synucleinopathy lesions
H Fujiwara et al.
NATURE CELL BIOLOGY (2002)