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Deglycosylated anti-amyloid-β antibodies eliminate cognitive deficits and reduce parenchymal amyloid with minimal vascular consequences in aged amyloid precursor protein transgenic mice
Donna M. Wilcock et al.
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PPAR-gamma agonists as regulators of microglial activation and brain inflammation
A Bernardo et al.
CURRENT PHARMACEUTICAL DESIGN (2006)
Apoptotic mechanisms and the synaptic pathology of schizophrenia
LA Glantz et al.
SCHIZOPHRENIA RESEARCH (2006)
Expression of nicotinic receptors on primary cultures of rat astrocytes and up-regulation of the α7, α4 and β2 subunits in response to nanomolar concentrations of the β-amyloid peptide1-42
J Xiu et al.
NEUROCHEMISTRY INTERNATIONAL (2005)
Acute treatment with the PPARγ agonist pioglitazone and ibuprofen reduces glial inflammation and Aβ1-42 levels in APPV717I transgenic mice
MT Heneka et al.
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Inflammatory cytokine levels correlate with amyloid load in transgenic mouse models of Alzheimer's disease
Nikunj S. Patel et al.
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Neuronal and nonneuronal quantitative BACE immunocytochemical expression in the entorhinohippocampal and frontal regions in Alzheimer's disease
G Leuba et al.
DEMENTIA AND GERIATRIC COGNITIVE DISORDERS (2005)
Alzheimer's disease beta-secretase BACE1 is not a neuron-specific enzyme
S Rossner et al.
JOURNAL OF NEUROCHEMISTRY (2005)
Passive amyloid immunotherapy clears amyloid and transiently activates microglia in a transgenic mouse model of amyloid deposition
DM Wilcock et al.
JOURNAL OF NEUROSCIENCE (2004)
Apolipoprotein E promotes astrocyte colocalization and degradation of deposited amyloid-β peptides
M Koistinaho et al.
NATURE MEDICINE (2004)
Expression of the small heat-shock protein alpha B-crystallin in tauopathies with glial pathology
DV Dabir et al.
AMERICAN JOURNAL OF PATHOLOGY (2004)
Non-steroidal anti-inflammatory drugs (NSAIDs) in Alzheimer's disease: old and new mechanisms of action
L Gasparini et al.
JOURNAL OF NEUROCHEMISTRY (2004)
Orally administered melatonin reduces oxidative stress and proinflammatory cytokines induced by amyloid-β peptide in rat brain:: a comparative, in vivo study versus vitamin C and E
S Rosales-Corral et al.
JOURNAL OF PINEAL RESEARCH (2003)
Intracranially administered anti-Aβ antibodies reduce β-amyloid deposition by mechanisms both independent of and associated with microglial activation
DM Wilcock et al.
JOURNAL OF NEUROSCIENCE (2003)
Decreased iNOS synthesis mediates dexamethasone-induced protection of neurons from inflammatory injury in vitro
S Golde et al.
EUROPEAN JOURNAL OF NEUROSCIENCE (2003)
A multicenter, placebo-controlled trial of melatonin for sleep disturbance in Alzheimer's disease
C Singer et al.
SLEEP (2003)
Alzheimer's amyloid beta-peptide enhances ATP/gap junction-mediated calcium-wave propagation in astrocytes
NJ Haughey et al.
NEUROMOLECULAR MEDICINE (2003)
IL-10 and glucocorticoids inhibit A beta(1-42) and lipopolysaccharide-induced pro-inflammatory cytokine and chemokine induction in the central nervous system
Ann Marie Szczepanik et al.
JOURNAL OF ALZHEIMERS DISEASE (2003)
Peroxisome proliferator-activated receptor-γ is a target of nonsteroidal anti-inflammatory drugs mediating cyclooxygenase-independent inhibition of lung cancer cell growth
M Wick et al.
MOLECULAR PHARMACOLOGY (2002)
Phosphorylation of glial fibrillary acidic protein is stimulated by glutamate via NMDA receptors in cortical microslices and in mixed neuronal/glial cell cultures prepared from the cerebellum
T Kommers et al.
DEVELOPMENTAL BRAIN RESEARCH (2002)
AP-1 as a regulator of cell life and death
E Shaulian et al.
NATURE CELL BIOLOGY (2002)
Randomized pilot study of nimesulide treatment in Alzheimer's disease
PS Aisen et al.
NEUROLOGY (2002)
Activation of peroxisome proliferator-activated receptor isoforms and inhibition of prostaglandin H2 synthases by ibuprofen, naproxen, and indomethacin
MS Jaradat et al.
BIOCHEMICAL PHARMACOLOGY (2001)
Ibuprofen decreases cytokine-induced amyloid beta production in neuronal cells
I Blasko et al.
NEUROBIOLOGY OF DISEASE (2001)
A subset of NSAIDs lower amyloidogenic Aβ42 independently of cyclooxygenase activity
S Weggen et al.
NATURE (2001)
Molecular consequences of activated microglia in the brain: overactivation induces apoptosis
B Liu et al.
JOURNAL OF NEUROCHEMISTRY (2001)
Costimulatory effects of interferon-γ and interleukin-1β or tumor necrosis factor α on the synthesis of aβ1-40 and aβ1-42 by human astrocytes
I Blasko et al.
NEUROBIOLOGY OF DISEASE (2000)
Ibuprofen suppresses plaque pathology and inflammation in a mouse model for Alzheimer's disease
GP Lim et al.
JOURNAL OF NEUROSCIENCE (2000)
Interleukin-1 promotes expression and phosphorylation of neurofilament and tau proteins in vivo
JG Sheng et al.
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β-amyloid stimulation of inducible nitric-oxide synthase in astrocytes is interleukin-1β- and tumor necrosis factor-α (TNFα)-dependent, and involves a TNFα receptor-associated factor- and NFκB-inducing kinase-dependent signaling mechanism
KT Akama et al.
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H Akiyama et al.
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Inflammatory mechanisms in Alzheimer's disease:: Inhibition of β-amyloid-stimulated proinflammatory responses and neurotoxicity by PPARγ agonists
CK Combs et al.
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