4.5 Article

Treatment Goals for Psoriasis as Measured by Patient Benefit Index: Results of a National Psoriasis Foundation Survey

期刊

ADVANCES IN THERAPY
卷 39, 期 6, 页码 2657-2667

出版社

SPRINGER
DOI: 10.1007/s12325-022-02124-2

关键词

Patient Needs Questionnaire; Patient Benefit Index; Psoriasis; Treatment goals

资金

  1. Eli Lilly and Company

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The survey results indicate that treatment preferences in patients with PsO may vary depending on factors such as age, severity, and gender. Different subgroups may have distinct treatment goals, highlighting the importance of individualized treatment decisions and optimizing patient outcomes.
Introduction This cross-sectional survey was conducted with National Psoriasis Foundation (NPF) to capture treatment perspectives and expectations in patients with psoriasis (PsO) using Patient Needs Questionnaire (PNQ) of Patient Benefit Index (PBI). Methods Adult participants with self-reported diagnosis of PsO responded to the PNQ portion of PBI by indicating how much they valued different treatment attributes. All the treatment goals were captured on a five-point Likert scale (0 = Not important, 4 = Very important). Treatment goals were obtained for overall population and subgroups based on severity of disease Patient Global Assessment (PGA), age, gender, and Dermatology Life Quality Index (DLQI) total score. All data were expressed as mean and standard deviation [SD]. Results A total of 1200 participants completed the survey (mean age 51.5 years). Top treatment goal in the overall population was to have confidence in the therapy (3.46 [1.01]). Unique to the higher severity subgroup (PGA >= 3), to find a clear diagnosis and therapy was a top five goal and to get better skin quickly was for those with lesser severity (PGA < 3). To be free of itching (3.36 [0.99]) was the unique goal in the < 40 age group whereas it was to get better skin quickly (3.27 [1.12]) in the >= 40 group. In women and men, to be free of itching (3.38 [1.13]) and to get better skin quickly (3.20 [1.09]) were top five goals, respectively. Patients with >= 10 DLQI scores expressed higher treatment goal to regain control of the disease (3.66 [0.67]) compared to those with <= 10 DLQI scores who expressed to have confidence in the therapy (3.40 [1.11]) as the topmost treatment goal. Conclusion Our results suggest that in patients with PsO, treatment preferences can vary with different characteristics such as age, severity, and gender as measured by using PNQ. Further exploration of this data will help inform treatment decisions and optimize patient outcomes.

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