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First-in-Humans Trial of an RNA Interference Therapeutic Targeting VEGF and KSP in Cancer Patients with Liver Involvement
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Therapeutic Silencing of Bcl-2 by Systemically Administered siRNA Nanotherapeutics Inhibits Tumor Growth by Autophagy and Apoptosis and Enhances the Efficacy of Chemotherapy in Orthotopic Xenograft Models of ER (-) and ER (+) Breast Cancer
Ibrahim Tekedereli et al.
MOLECULAR THERAPY-NUCLEIC ACIDS (2013)
Nanoparticle-Based Delivery of RNAi Therapeutics: Progress and Challenges
Jiehua Zhou et al.
PHARMACEUTICALS (2013)
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The Effect of Nanoparticle Polyethylene Glycol Surface Density on Ligand-Directed Tumor Targeting Studied in Vivo by Dual Modality Imaging
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ACS NANO (2012)
Interactions of nanomaterials and biological systems: Implications to personalized nanomedicine
Xue-Qing Zhang et al.
ADVANCED DRUG DELIVERY REVIEWS (2012)
RNAi-based nanomedicines for targeted personalized therapy
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ADVANCED DRUG DELIVERY REVIEWS (2012)
The Effect of Nanoparticle Size, Shape, and Surface Chemistry on Biological Systems
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ANNUAL REVIEW OF BIOMEDICAL ENGINEERING, VOL 14 (2012)
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INTERNATIONAL JOURNAL OF CLINICAL PHARMACOLOGY AND THERAPEUTICS (2012)
Virus-mediated gene delivery for human gene therapy
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JOURNAL OF CONTROLLED RELEASE (2012)
Formulation approaches to short interfering RNA and MicroRNA: Challenges and implications
Diana Guzman-Villanueva et al.
JOURNAL OF PHARMACEUTICAL SCIENCES (2012)
Targeted Silencing of Elongation Factor 2 Kinase Suppresses Growth and Sensitizes Tumors to Doxorubicin in an Orthotopic Model of Breast Cancer
Ibrahim Tekedereli et al.
PLOS ONE (2012)
miR-34 – a microRNA replacement therapy is headed to the clinic
Andreas G. Bader
Frontiers in Genetics (2012)
Tumor delivery of macromolecular drugs based on the EPR effect
Vladimir Torchilin
ADVANCED DRUG DELIVERY REVIEWS (2011)
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ADVANCED DRUG DELIVERY REVIEWS (2011)
Hallmarks of Cancer: The Next Generation
Douglas Hanahan et al.
CELL (2011)
Recent advances of siRNA delivery by nanoparticles
Xudong Yuan et al.
EXPERT OPINION ON DRUG DELIVERY (2011)
Accumulation of sub-100 nm polymeric micelles in poorly permeable tumours depends on size
H. Cabral et al.
NATURE NANOTECHNOLOGY (2011)
RNA interference in the clinic: challenges and future directions
Chad V. Pecot et al.
NATURE REVIEWS CANCER (2011)
Effects of particle size and surface charge on cellular uptake and biodistribution of polymeric nanoparticles
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BIOMATERIALS (2010)
Atu027 Prevents Pulmonary Metastasis in Experimental and Spontaneous Mouse Metastasis Models
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CLINICAL CANCER RESEARCH (2010)
Nanoparticles for Tumor Targeted Therapies and Their Pharmacokinetics
Jianqiu Wang et al.
CURRENT DRUG METABOLISM (2010)
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Thomas Kaasgaard et al.
EXPERT OPINION ON DRUG DELIVERY (2010)
Efficient and targeted delivery of siRNA in vivo
Min Suk Shim et al.
FEBS JOURNAL (2010)
The role of HER2 in cancer therapy and targeted drug delivery
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JOURNAL OF CONTROLLED RELEASE (2010)
Nanomedicine based approaches for the delivery of siRNA in cancer
B. Ozpolat et al.
JOURNAL OF INTERNAL MEDICINE (2010)
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Evidence of RNAi in humans from systemically administered siRNA via targeted nanoparticles
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NATURE (2010)
Rational design of cationic lipids for siRNA delivery
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NATURE BIOTECHNOLOGY (2010)
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NATURE CELL BIOLOGY (2010)
Peptide- and polymer-based delivery of therapeutic RNA
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SOFT MATTER (2010)
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Lipidic Systems for In Vivo siRNA Delivery
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AAPS JOURNAL (2009)
Biological Barriers to Therapy with Antisense and siRNA Oligonucleotides
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MOLECULAR PHARMACEUTICS (2009)
The First Targeted Delivery of siRNA in Humans via a Self-Assembling, Cyclodextrin Polymer-Based Nanoparticle: From Concept to Clinic
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MOLECULAR PHARMACEUTICS (2009)
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CANCER RESEARCH (2008)
Anticancer therapeutics: Targeting macromolecules and nanocarriers to hyaluronan or CD44, a hyaluronan receptor
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Central delivery of Dicer-substrate siRNA:: A direct application for pain research
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MOLECULAR THERAPY (2008)
PSA fluoroimmunoassays using anti-PSA ScFv and quantum-dot conjugates
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Wen Jiang et al.
NATURE NANOTECHNOLOGY (2008)
Nanoparticles for drug delivery in cancer treatment
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UROLOGIC ONCOLOGY-SEMINARS AND ORIGINAL INVESTIGATIONS (2008)
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Dan Peer et al.
NATURE NANOTECHNOLOGY (2007)
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CANCER AND METASTASIS REVIEWS (2007)
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NATURE REVIEWS DRUG DISCOVERY (2007)
Administration in non-human primates of escalating intravenous doses of targeted nanoparticles containing ribonucleotide reductase subunit M2 siRNA
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Potent siRNA inhibitors of ribonucleotide reductase subunit RRM2 reduce cell proliferation in vitro and in vivo
Jeremy D. Heidel et al.
CLINICAL CANCER RESEARCH (2007)
Toxicity of cationic lipids and cationic polymers in gene delivery
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JOURNAL OF CONTROLLED RELEASE (2006)
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GENE THERAPY (2006)
3′ UTR seed matches, but not overall identity, are associated with RNAi off-targets
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GENE THERAPY (2006)
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CANCER RESEARCH (2005)
Immunogenicity of engineered antibodies
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METHODS (2005)
被撤回的出版物: EphA2: a determinant of malignant cellular behavior and a potential therapeutic target in pancreatic adenocarcinoma (Retracted article. See FEB, 2023)
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CANCER RESEARCH (2004)
EphA2 expression is associated with aggressive features in ovarian carcinoma
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