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Pharmacokinetics and modeling of immune cell trafficking: quantifying differential influences of target tissues versus lymphocytes in SJL and lipopolysaccharide-treated mice
William A. Banks et al.
JOURNAL OF NEUROINFLAMMATION (2012)
Macrophages Promote Fibroblast Growth Factor Receptor-Driven Tumor Cell Migration and Invasion in a Cxcr2-Dependent Manner
Laura R. Bohrer et al.
MOLECULAR CANCER RESEARCH (2012)
A critical evaluation of in vitro cell culture models for high-throughput drug screening and toxicity
Anna Astashkina et al.
PHARMACOLOGY & THERAPEUTICS (2012)
Screening of Budesonide Nanoformulations for Treatment of Inflammatory Bowel Disease in an Inflamed 3D Cell-Culture Model
Fransisca Leonard et al.
ALTEX-ALTERNATIVES TO ANIMAL EXPERIMENTATION (2012)
T Lymphocyte Potential Marks the Emergence of Definitive Hematopoietic Progenitors in Human Pluripotent Stem Cell Differentiation Cultures
Marion Kennedy et al.
CELL REPORTS (2012)
Quantitative Assessment of Normal Soft-Tissue Elasticity Using Shear-Wave Ultrasound Elastography
Kemal Arda et al.
AMERICAN JOURNAL OF ROENTGENOLOGY (2011)
Tumor-Associated Macrophages Promote Angiogenesis and Melanoma Growth via Adrenomedullin in a Paracrine and Autocrine Manner
Peiwen Chen et al.
CLINICAL CANCER RESEARCH (2011)
STRUCTURE AND FUNCTION OF THE SKELETAL MUSCLE EXTRACELLULAR MATRIX
Allison R. Gillies et al.
MUSCLE & NERVE (2011)
Melanoma Spheroids Grown Under Neural Crest Cell Conditions Are Highly Plastic Migratory/Invasive Tumor Cells Endowed with Immunomodulator Function
Kiran Ramgolam et al.
PLOS ONE (2011)
Regulation of tumor invasion by interstitial fluid flow
Adrian C. Shieh et al.
PHYSICAL BIOLOGY (2011)
Notch Signaling Determines the M1 versus M2 Polarization of Macrophages in Antitumor Immune Responses
Yao-Chun Wang et al.
CANCER RESEARCH (2010)
Macrophage Expression of Hypoxia-Inducible Factor-1α Suppresses T-Cell Function and Promotes Tumor Progression
Andrew L. Doedens et al.
CANCER RESEARCH (2010)
Transmural Flow Modulates Cell and Fluid Transport Functions of Lymphatic Endothelium
Dimana O. Miteva et al.
CIRCULATION RESEARCH (2010)
Immunological substance testing on human lymphatic micro-organoids in vitro
Christoph Giese et al.
JOURNAL OF BIOTECHNOLOGY (2010)
Paracellular Porosity and Pore Size of the Human Intestinal Epithelium in Tissue and Cell Culture Models
Johanna Linnankoski et al.
JOURNAL OF PHARMACEUTICAL SCIENCES (2010)
A Three-Dimensional Coculture of Enterocytes, Monocytes and Dendritic Cells To Model Inflamed Intestinal Mucosa in Vitro
Fransisca Leonard et al.
MOLECULAR PHARMACEUTICS (2010)
Polymer Scaffolds for Biomaterials Applications
Molly S. Shoichet
MACROMOLECULES (2010)
Reconstituting Organ-Level Lung Functions on a Chip
Dongeun Huh et al.
SCIENCE (2010)
In vitro antibody response to tetanus in the MIMIC™ system is a representative measure of vaccine immunogenicity
Anthony M. Byers et al.
BIOLOGICALS (2009)
In vitro end points for the assessment of cellular immune response-modulating drugs
Maria Pia Fuggetta et al.
EXPERT OPINION ON DRUG DISCOVERY (2009)
Fluid Flow Regulates Stromal Cell Organization and CCL21 Expression in a Tissue-Engineered Lymph Node Microenvironment
Alice A. Tomei et al.
JOURNAL OF IMMUNOLOGY (2009)
Physiologic upper limit of pore size in the blood-tumor barrier of malignant solid tumors
Hemant Sarin et al.
JOURNAL OF TRANSLATIONAL MEDICINE (2009)
Graft-versus-host disease
James L. M. Ferrara et al.
LANCET (2009)
Collagen-based cell migration models in vitro and in vivo
Katarina Wolf et al.
SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY (2009)
An Immunologic Model for Rapid Vaccine Assessment - A Clinical Trial in a Test Tube
Russell G. Higbee et al.
ATLA-ALTERNATIVES TO LABORATORY ANIMALS (2009)
A tense situation: forcing tumour progression
Darci T. Butcher et al.
NATURE REVIEWS CANCER (2009)
Methods for Predicting In Vivo Pharmacokinetics Using Data from In Vitro Assays
J. Brian Houston et al.
CURRENT DRUG METABOLISM (2008)
Rapid leukocyte migration by integrin-independent flowing and squeezing
Tim Laemmermann et al.
NATURE (2008)
Derive and conquer: sourcing and differentiating stem cells for therapeutic applications
Irina Klimanskaya et al.
NATURE REVIEWS DRUG DISCOVERY (2008)
Diffusion in brain extracellular space
Eva Sykova et al.
PHYSIOLOGICAL REVIEWS (2008)
Physiologically based approaches towards the prediction of pharmacokinetics:: in vitro-in vivo extrapolation
Stefan S. De Buck et al.
EXPERT OPINION ON DRUG METABOLISM & TOXICOLOGY (2007)
Producing primate embryonic stem cells by somatic cell nuclear transfer
J. A. Byrne et al.
NATURE (2007)
Patient-specific stem cell lines derived from human parthenogenetic blastocysts
E. S. Revazova et al.
CLONING AND STEM CELLS (2007)
Multiple mechanisms underlie defective recognition of melanoma cells cultured in three-dimensional architectures by antigen-specific cytotoxic T lymphocytes
C. Feder-Mengus et al.
BRITISH JOURNAL OF CANCER (2007)
Tumor-induced sentinel lymph node lymphangiogenesis and increased lymph flow precede melanoma metastasis
Maria I. Harrell et al.
AMERICAN JOURNAL OF PATHOLOGY (2007)
Immunomodulatory oligonucleotides as novel therapy for breast cancer:: pharmacokinetics, in vitro and in vivo anticancer activity, and potentiation of antibody therapy
Hui Wang et al.
MOLECULAR CANCER THERAPEUTICS (2006)
Influence of donor/recipient sex matching on outcome of allogeneic hematopoietic stem cell transplantation for aplastic anemia
Martin Stern et al.
TRANSPLANTATION (2006)
The role of human glioma-infiltrating microglia/macrophages in mediating antitumor immune responses
S. Farzana Hussain et al.
NEURO-ONCOLOGY (2006)
Lymph node metastasis in breast cancer xenografts is associated with increased regions of extravascular drain, lymphatic vessel area, and invasive phenotype
Arvind P. Pathak et al.
CANCER RESEARCH (2006)
Lab-on-a-chip: microfluidics in drug discovery
PS Dittrich et al.
NATURE REVIEWS DRUG DISCOVERY (2006)
ES cells derived from cloned and fertilized blastocysts are transcriptionally and functionally indistinguishable
T Brambrink et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2006)
Macrophages promote angiogenesis in human breast tumour spheroids in vivo
L Bingle et al.
BRITISH JOURNAL OF CANCER (2006)
Culture of melanoma cells in 3-dimensional architectures results in impaired immunorecognition by cytotoxic T lymphocytes specific for Melan-A/MART-1 tumor-associated antigen
S Ghosh et al.
ANNALS OF SURGERY (2005)
CXCR3 activation promotes lymphocyte transendothelial migration across human hepatic endothelium under fluid flow
SM Curbishley et al.
AMERICAN JOURNAL OF PATHOLOGY (2005)
Microregional extracellular matrix heterogeneity in brain modulates glioma cell invasion
AC Bellail et al.
INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY (2004)
Pharmacokinetics of alemtuzumab used for in vivo and in vitro T-cell depletion in allogeneic transplantations: relevance for early adoptive immunotherapy and infectious complications
EC Morris et al.
BLOOD (2003)
Diffusion parameters of the extracellular space in human gliomas
L Vargová et al.
GLIA (2003)
Amoeboid shape change and contact guidance: T-lymphocyte crawling through fibrillar collagen is independent of matrix remodeling by MMPs and other proteases
K Wolf et al.
BLOOD (2003)
Calcein-acetyoxymethyl cytotoxicity assay: Standardization of a method allowing additional analyses on recovered effector cells and supernatants
S Neri et al.
CLINICAL AND DIAGNOSTIC LABORATORY IMMUNOLOGY (2001)
Forecasting the growth of multicell tumour spheroids: implications for the dynamic growth of solid tumours
R Chignola et al.
CELL PROLIFERATION (2000)
Drug release from biodegradable injectable thermosensitive hydrogel of PEG-PLGA-PEG triblock copolymers
B Jeong et al.
JOURNAL OF CONTROLLED RELEASE (2000)
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