Recent advances in biomedical applications of 2D nanomaterials with peroxidase-like properties

Significant progress has been made in developing two-dimensional (2D) nanomaterials owing to their ultra-thin structure, high specific surface area, and many other advantages. Recently, 2D nanomaterials with enzyme-like properties, especially peroxidase (POD)-like activity, are highly desirable for many biomedical applications. In this review, we first classify the types of 2D POD-like nanomaterials and then summarize various strategies for endowing 2D nanomaterials with POD-like properties. Representative examples of biomedical applications are reviewed, emphasizing in antibacterial, biosensing, and cancer therapy. Last, the future challenges and prospects of 2D POD-like nanomaterials are discussed. This review is expected to provide an in-depth understanding of 2D POD-like materials for biomedical applications. (C) 2022 Elsevier B.V. All rights reserved.

Automated summary

This review highlights the significance of 2D nanomaterials with enzyme-like properties, particularly peroxidase (POD)-like activity, in biomedical applications. The classification of different types of 2D POD-like nanomaterials is presented, along with various strategies to impart POD-like properties to these materials. The review focuses on representative examples of biomedical applications, including antibacterial, biosensing, and cancer therapy. The future challenges and prospects of 2D POD-like nanomaterials are also discussed.