相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。A multiplexed, automated evolution pipeline enables scalable discovery and characterization of biosensors
Brent Townshend et al.
NATURE COMMUNICATIONS (2021)
Engineering L7Ae for RNA-Only Delivery Kill Switch Targeting CMS2 Type Colorectal Cancer Cells
Jiong Yang et al.
ACS SYNTHETIC BIOLOGY (2021)
Highly accurate protein structure prediction with AlphaFold
John Jumper et al.
NATURE (2021)
Accurate prediction of protein structures and interactions using a three-track neural network
Minkyung Baek et al.
SCIENCE (2021)
Context-aware synthetic biology by controller design: Engineering the mammalian cell
Nika Shakiba et al.
CELL SYSTEMS (2021)
Recent advances in de novo protein design: Principles, methods, and applications
Xingjie Pan et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2021)
Light-controllable RNA-protein devices for translational regulation of synthetic mRNAs in mammalian cells
Hideyuki Nakanishi et al.
CELL CHEMICAL BIOLOGY (2021)
A Combinatorial Library of Lipid Nanoparticles for RNA Delivery to Leukocytes
Srinivas Ramishetti et al.
ADVANCED MATERIALS (2020)
N1-Methylpseudouridine substitution enhances the performance of synthetic mRNA switches in cells
Callum J. C. Parr et al.
NUCLEIC ACIDS RESEARCH (2020)
Orthogonal Protein-Responsive mRNA Switches for Mammalian Synthetic Biology
Hiroki Ono et al.
ACS SYNTHETIC BIOLOGY (2020)
Daisy Chain Topology Based Mammalian Synthetic Circuits for RNA-Only Delivery
Kaiyu Liu et al.
ACS SYNTHETIC BIOLOGY (2020)
Regulation of mRNA translation by a photoriboswitch
Kelly A. Rotstan et al.
ELIFE (2020)
Caliciviral protein-based artificial translational activator for mammalian gene circuits with RNA-only delivery
Hideyuki Nakanishi et al.
NATURE COMMUNICATIONS (2020)
Selective organ targeting (SORT) nanoparticles for tissue-specific mRNA delivery and CRISPR-Cas gene editing
Qiang Cheng et al.
NATURE NANOTECHNOLOGY (2020)
Programmable Synthetic Protein Circuits for the Identification and Suppression of Hepatocellular Carcinoma
Xu Han et al.
MOLECULAR THERAPY-ONCOLYTICS (2020)
Pluripotent Stem Cell-Based Cell Therapy- Promise and Challenges
Shinya Yamanaka
CELL STEM CELL (2020)
Artificial Protein-Responsive Riboswitches Upregulate Non-AUG Translation Initiation in Yeast
Fumihiro Horie et al.
ACS SYNTHETIC BIOLOGY (2020)
Phosphodiester modifications in mRNA poly(A) tail prevent deadenylation without compromising protein expression
Dominika Strzelecka et al.
RNA (2020)
Characterization and mitigation of gene expression burden in mammalian cells
Timothy Frei et al.
NATURE COMMUNICATIONS (2020)
Genetic circuit characterization by inferring RNA polymerase movement and ribosome usage
Amin Espah Borujeni et al.
NATURE COMMUNICATIONS (2020)
An endoribonuclease-based feedforward controller for decoupling resource-limited genetic modules in mammalian cells
Ross D. Jones et al.
NATURE COMMUNICATIONS (2020)
Delivery Aspects of CRISPR/Cas for in Vivo Genome Editing
Danny Wilbie et al.
ACCOUNTS OF CHEMICAL RESEARCH (2019)
Cell-specific CRISPR-Cas9 activation by microRNA-dependent expression of anti-CRISPR proteins
Mareike D. Hoffmann et al.
NUCLEIC ACIDS RESEARCH (2019)
High-Throughput Analysis Reveals Rules for Target RNA Binding and Cleavage by AGO2
Winston R. Becker et al.
MOLECULAR CELL (2019)
Cell-Type-Specific CRISPR Activation with MicroRNA-Responsive AcrllA4 Switch
Moe Hirosawa et al.
ACS SYNTHETIC BIOLOGY (2019)
A blue light receptor that mediates RNA binding and translational regulation
Anna M. Weber et al.
NATURE CHEMICAL BIOLOGY (2019)
Tissue-restricted genome editing in vivo specified by microRNA-repressible anti-CRISPR proteins
Jooyoung Lee et al.
RNA (2019)
Numerical operations in living cells by programmable RNA devices
Kei Endo et al.
SCIENCE ADVANCES (2019)
Massively parallel RNA device engineering in mammalian cells with RNA-Seq
Joy S. Xiang et al.
NATURE COMMUNICATIONS (2019)
The biochemical basis of microRNA targeting efficacy
Sean E. McGeary et al.
SCIENCE (2019)
Functional 5′ UTR mRNA structures in eukaryotic translation regulation and how to find them
Kathrin Leppek et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2018)
Oncogenic Signaling Pathways in The Cancer Genome Atlas
Francisco Sanchez-Vega et al.
CELL (2018)
Mixed tailing by TENT4A and TENT4B shields mRNA from rapid deadenylation
Jaechul Lim et al.
SCIENCE (2018)
A mixed antagonistic/synergistic miRNA repression model enables accurate predictions of multi-input miRNA sensor activity
Jeremy J. Gam et al.
NATURE COMMUNICATIONS (2018)
Synthetic gene circuits for the detection, elimination and prevention of disease
Ferdinand Sedlmayer et al.
NATURE BIOMEDICAL ENGINEERING (2018)
Small-molecule-based regulation of RNA-delivered circuits in mammalian cells
Tyler E. Wagner et al.
NATURE CHEMICAL BIOLOGY (2018)
High-throughput in vivo screen of functional mRNA delivery identifies nanoparticles for endothelial cell gene editing
Cory D. Sago et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2018)
Engineering protein-protein devices for multilayered regulation of mRNA translation using orthogonal proteases in mammalian cells
Federica Cella et al.
NATURE COMMUNICATIONS (2018)
Synthetic RNA-based logic computation in mammalian cells
Satoshi Matsuura et al.
NATURE COMMUNICATIONS (2018)
Bringing Light to Transcription: The Optogenetics Repertoire
Lorena de Mena et al.
FRONTIERS IN GENETICS (2018)
Large-scale design of robust genetic circuits with multiple inputs and outputs for mammalian cells
Benjamin H. Weinberg et al.
NATURE BIOTECHNOLOGY (2017)
Cell-type-specific genome editing with a microRNA-responsive CRISPR-Cas9 switch
Moe Hirosawa et al.
NUCLEIC ACIDS RESEARCH (2017)
Synthetic mRNA devices that detect endogenous proteins and distinguish mammalian cells
Shunsuke Kawasaki et al.
NUCLEIC ACIDS RESEARCH (2017)
Synthetic RNA-Based Immunomodulatory Gene Circuits for Cancer Immunotherapy
Lior Nissim et al.
CELL (2017)
Monitoring and visualizing microRNA dynamics during live cell differentiation using microRNA-responsive non-viral reporter vectors
Hideyuki Nakanishi et al.
BIOMATERIALS (2017)
Synthetic Riboswitches: From Plug and Pray toward Plug and Play
Maja Etzel et al.
BIOCHEMISTRY (2017)
Engineering Translational Activators with CRISPR-Cas System
Pei Du et al.
ACS SYNTHETIC BIOLOGY (2016)
LIN28 Regulates Stem Cell Metabolism and Conversion to Primed Pluripotency
Jin Zhang et al.
CELL STEM CELL (2016)
Rational design of a synthetic mammalian riboswitch as a ligand-responsive-1 ribosomal frame-shifting stimulator
Ya-Hui Lin et al.
NUCLEIC ACIDS RESEARCH (2016)
Genetic circuit design automation
Alec A. K. Nielsen et al.
SCIENCE (2016)
MicroRNA-302 switch to identify and eliminate undifferentiated human pluripotent stem cells
Callum J. C. Parr et al.
SCIENTIFIC REPORTS (2016)
High-resolution Identification and Separation of Living Cell Types by Multiple microRNA-responsive Synthetic mRNAs
Kei Endo et al.
SCIENTIFIC REPORTS (2016)
Efficient Detection and Purification of Cell Populations Using Synthetic MicroRNA Switches
Kenji Miki et al.
CELL STEM CELL (2015)
CRISPR-Cas9-based Photoactivatable Transcription System
Yuta Nihongaki et al.
CHEMISTRY & BIOLOGY (2015)
N1-methylpseudouridine-incorporated mRNA outperforms pseudouridine-incorporated mRNA by providing enhanced protein expression and reduced immunogenicity in mammalian cell lines and mice
Oliwia Andries et al.
JOURNAL OF CONTROLLED RELEASE (2015)
Sequence-engineered mRNA Without Chemical Nucleoside Modifications Enables an Effective Protein Therapy in Large Animals
Andreas Thess et al.
MOLECULAR THERAPY (2015)
Mammalian synthetic circuits with RNA binding proteins for RNA-only delivery
Liliana Wroblewska et al.
NATURE BIOTECHNOLOGY (2015)
A light-inducible CRISPR-Cas9 system for control of endogenous gene activation
Lauren R. Polstein et al.
NATURE CHEMICAL BIOLOGY (2015)
NON-CODING RNA Towards a molecular understanding of microRNA-mediated gene silencing
Stefanie Jonas et al.
NATURE REVIEWS GENETICS (2015)
A universal strategy for regulating mRNA translation in prokaryotic and eukaryotic cells
Jicong Cao et al.
NUCLEIC ACIDS RESEARCH (2015)
Controlling mRNA stability and translation with the CRISPR endoribonuclease Csy4
Erin K. Borchardt et al.
RNA (2015)
Model-Driven Engineering of Gene Expression from RNA Replicons
Jacob Beal et al.
ACS SYNTHETIC BIOLOGY (2015)
Bidirectional Regulation of mRNATranslation in Mammalian Cells by Using PUF Domains
Jicong Cao et al.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2014)
Multiplexed and Programmable Regulation of Gene Networks with an Integrated RNA and CRISPR/Cas Toolkit in Human Cells
Lior Nissim et al.
MOLECULAR CELL (2014)
TAIL-seq: Genome-wide Determination of Poly(A) Tail Length and 3′ End Modifications
Hyeshik Chang et al.
MOLECULAR CELL (2014)
A general design strategy for protein-responsive riboswitches in mammalian cells
Simon Auslaender et al.
NATURE METHODS (2014)
Protein-responsive ribozyme switches in eukaryotic cells
Andrew B. Kennedy et al.
NUCLEIC ACIDS RESEARCH (2014)
Cap analogs containing 6-thioguanosine - reagents for the synthesis of mRNAs selectively photo-crosslinkable with cap-binding biomolecules
Monika Nowakowska et al.
ORGANIC & BIOMOLECULAR CHEMISTRY (2014)
Engineering RNA-binding proteins for biology
Yu Chen et al.
FEBS JOURNAL (2013)
Optical control of mammalian endogenous transcription and epigenetic states
Silvana Konermann et al.
NATURE (2013)
Modified mRNA directs the fate of heart progenitor cells and induces vascular regeneration after myocardial infarction
Lior Zangi et al.
NATURE BIOTECHNOLOGY (2013)
Tumorigenicity as a clinical hurdle for pluripotent stem cell therapies
Andrew S. Lee et al.
NATURE MEDICINE (2013)
Quantitative and simultaneous translational control of distinct mammalian mRNAs
Kei Endo et al.
NUCLEIC ACIDS RESEARCH (2013)
Controlling Mammalian Gene Expression by Allosteric Hepatitis Delta Virus Ribozymes
Yoko Nomura et al.
ACS SYNTHETIC BIOLOGY (2013)
A triple helix stabilizes the 3′ ends of long noncoding RNAs that lack poly(A) tails
Jeremy E. Wilusz et al.
GENES & DEVELOPMENT (2012)
Programmable single-cell mammalian biocomputers
Simon Auslaender et al.
NATURE (2012)
Three-dimensionally designed protein-responsive RNA devices for cell signaling regulation
Shunnichi Kashida et al.
NUCLEIC ACIDS RESEARCH (2012)
Direct and specific chemical control of eukaryotic translation with a synthetic RNA-protein interaction
Stephen J. Goldfless et al.
NUCLEIC ACIDS RESEARCH (2012)
Feedback Control of Protein Expression in Mammalian Cells by Tunable Synthetic Translational Inhibition
James A. Stapleton et al.
ACS SYNTHETIC BIOLOGY (2012)
Lin28A and Lin28B Inhibit let-7 MicroRNA Biogenesis by Distinct Mechanisms
Elena Piskounova et al.
CELL (2011)
SIRPA is a specific cell-surface marker for isolating cardiomyocytes derived from human pluripotent stem cells
Nicole C. Dubois et al.
NATURE BIOTECHNOLOGY (2011)
Design of small molecule-responsive microRNAs based on structural requirements for Drosha processing
Chase L. Beisel et al.
NUCLEIC ACIDS RESEARCH (2011)
Multi-Input RNAi-Based Logic Circuit for Identification of Specific Cancer Cells
Zhen Xie et al.
SCIENCE (2011)
Engineering a Direct and Inducible Protein-RNA Interaction To Regulate RNA Biology
Brian J. Belmont et al.
ACS CHEMICAL BIOLOGY (2010)
Highly Efficient Reprogramming to Pluripotency and Directed Differentiation of Human Cells with Synthetic Modified mRNA
Luigi Warren et al.
CELL STEM CELL (2010)
Targeted Delivery of RNAi Therapeutics With Endogenous and Exogenous Ligand-Based Mechanisms
Akin Akinc et al.
MOLECULAR THERAPY (2010)
Synthetic translational regulation by an L7Ae-kink-turn RNP switch
Hirohide Saito et al.
NATURE CHEMICAL BIOLOGY (2010)
Rationally designed logic integration of regulatory signals in mammalian cells
Madeleine Leisner et al.
NATURE NANOTECHNOLOGY (2010)
Incorporation of pseudouridine into mRNA enhances translation by diminishing PKR activation
Bart R. Anderson et al.
NUCLEIC ACIDS RESEARCH (2010)
Target RNA-Directed Trimming and Tailing of Small Silencing RNAs
Stefan L. Ameres et al.
SCIENCE (2010)
MicroRNAs: Target Recognition and Regulatory Functions
David P. Bartel
CELL (2009)
Light-activation of gene function in mammalian cells via ribozymes
Douglas D. Young et al.
CHEMICAL COMMUNICATIONS (2009)
Conditional RNA Interference Mediated by Allosteric Ribozyme
Deepak Kumar et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2009)
Incorporation of Pseudouridine Into mRNA Yields Superior Nonimmunogenic Vector With Increased Translational Capacity and Biological Stability
Katalin Kariko et al.
MOLECULAR THERAPY (2008)
Lin-28 interaction with the Let-7 precursor loop mediates regulated microRNA processing
Martin A. Newman et al.
RNA (2008)
Higher-order cellular information processing with synthetic RNA devices
Maung Nyan Win et al.
SCIENCE (2008)
Structures of human Pumilio with noncognate RNAs reveal molecular mechanisms for binding promiscuity
Yogesh K. Gupta et al.
STRUCTURE (2008)
Screening for engineered neomycin riboswitches that control translation initiation
Julia E. Weigand et al.
RNA (2008)
A modular and extensible RNA-based gene-regulatory platform for engineering cellular function
Maung Nyan Win et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2007)
A universal RNAi-based logic evaluator that operates in mammalian cells
Keller Rinaudo et al.
NATURE BIOTECHNOLOGY (2007)
Tetracycline aptamer-controlled regulation of pre-mRNA splicing in yeast
Julia E. Weigand et al.
NUCLEIC ACIDS RESEARCH (2007)
Different modes and potencies of translational repression by sequence-specific RNA-protein interaction at the 5′-UTR
Minghua Nie et al.
NUCLEIC ACIDS RESEARCH (2006)
Engineering RNA sequence specificity of Pumilio repeats
Cheorn-Gil Cheong et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2006)
Designing siRNA that distinguish between genes that differ by a single nucleotide
Dianne S. Schwarz et al.
PLOS GENETICS (2006)
Identification of inhibitors of ribozyme self-cleavage in mammalian cells via high-throughput screening of chemical libraries
LS Yen et al.
RNA (2006)
Suppression of RNA recognition by Toll-like receptors:: The impact of nucleoside modification and the evolutionary origin of RNA
K Karikó et al.
IMMUNITY (2005)
Exogenous control of mammalian gene expression through modulation of RNA self-cleavage
L Yen et al.
NATURE (2004)
Novel anti-reverse cap analogs with superior translational properties
J Jemielity et al.
RNA (2003)
Tetracycline-aptamer-mediated translational regulation in yeast
S Hanson et al.
MOLECULAR MICROBIOLOGY (2003)
A synthetic oscillatory network of transcriptional regulators
MB Elowitz et al.
NATURE (2000)