期刊
ACTA OPHTHALMOLOGICA
卷 100, 期 7, 页码 813-818出版社
WILEY
DOI: 10.1111/aos.15121
关键词
cataract surgery; diabetic retinopathy; intravitreal injection; posterior capsular rupture; posterior capsular tear; type 2 diabetes mellitus
资金
- Research to Prevent Blindness, Inc.
This study aims to determine whether type 2 diabetes is an independent risk factor for posterior capsular rupture during cataract surgery, taking into account diabetic retinopathy and previous intravitreal anti-VEGF injections. The results show that diabetic retinopathy and previous intravitreal injections are risk factors for posterior capsular rupture.
PurposeTo determine whether type 2 diabetes mellitus (T2DM) with and without diabetic retinopathy (DR) is independent risk factor for posterior capsular rupture (PCR) during cataract surgery. MethodsA retrospective study was conducted from 2014 to 2019. Patients from the University of Colorado Cataract Outcomes Database who had undergone phacoemulsification cataract surgery were included. Patients with traumatic, congenital or polar cataracts, type 1 diabetes or less than 18years old were excluded. The primary outcome was incidence of PCR during surgery in patients with T2DM with and without DR, accounting for previous intravitreal anti-VEGF injections (IVI). ResultsA total of 6636 patients were included. A PCR occurred in 59 (0.5%) of 10893 eyes studied: 35 (0.4%) eyes in patients without diabetes, comparatively to 13 (0.7%) eyes with T2DM without DR (p=0.142) and 11 (1.8%) eyes with DR (p<0.0001). All groups with previous IVI demonstrated a significant increase in PCR compared with eyes without IVI or T2DM. In the absence of IVI, T2DM without DR was not significant (p=0.520), but T2DM with DR had a significantly increased risk of PCR in univariate analysis (OR 3.55, 95% CI: 1.49,8.50, p=0.004) and an increased risk of borderline significance in multivariate analysis (AOR 2.33, 95% CI: 0.98, 5.56, p=0.056). ConclusionPrevious IVI is an independent risk factor for PCR. Diabetic retinopathy without previous IVI is likely a risk factor but was of borderline significance due to small sample size. Consideration of PCR risk should be given during surgical planning for patients with DR and/or previous IVI.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据