Acute autonomic dysregulation due to HHV-6 encephalitis in an immunocompromised patient: a case report and literature review

Human herpesvirus-6 (HHV-6), in particularly HHV-6B, can reactivate in immunocompromised patients. Especially after stem cell transplantation, reactivation of HHV-6 can cause complications, such as limbic encephalitis. We present a case of a 61-year-old man with B-cell non-Hodgkin lymphoma. He presented with subacute lethargy, confusion and hyperhidrosis. Following this, we will give a short review of the literature considering clinical and technical features as well as treatment options.

Automated summary

In this case report, a 61-year-old man with B-cell non-Hodgkin lymphoma presented with subacute lethargy, confusion, and hyperhidrosis. This suggests that HHV-6 can reactivate in immunocompromised patients, leading to complications.