4.8 Article

Optical Nanosensor for Intracellular and Intracranial Detection of Amyloid-Beta

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In-vitro and in-vivo characterization of CRANAD-2 for multi-spectral optoacoustic tomography and fluorescence imaging of amyloid-beta deposits in Alzheimer mice

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Summary: The study introduces a novel optical detection method, CRANAD-2, which can specifically and quantitatively detect Aβ deposits in the brain of AD animal models, facilitating research on AD pathological mechanisms and monitoring potential treatments targeting Aβ deposits.

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