相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。Tunable Methacrylamides for Covalent Ligand Directed Release Chemistry
Rambabu N. Reddi et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2021)
The Role of BANK1 in B Cell Signaling and Disease
Gonzalo Gomez Hernandez et al.
CELLS (2021)
Role of NFAT in Chronic Lymphocytic Leukemia and Other B-Cell Malignancies
Ilenia Sana et al.
FRONTIERS IN ONCOLOGY (2021)
Click Chemistry in Proteomic Investigations
Christopher G. Parker et al.
CELL (2020)
Biochemical characterization of tirabrutinib and other irreversible inhibitors of Bruton's tyrosine kinase reveals differences in on - and off - target inhibition
Albert Liclican et al.
BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS (2020)
2-Sulfonylpyridines as Tunable, Cysteine-Reactive Electrophiles
Claudio Zambaldo et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2020)
B cell development is critically dependent on NFATc1 activity
Sabrina Giampaolo et al.
CELLULAR & MOLECULAR IMMUNOLOGY (2019)
The Proteome-Wide Potential for Reversible Covalency at Cysteine
Kristine Senkane et al.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2019)
Emerging and Re-Emerging Warheads for Targeted Covalent Inhibitors: Applications in Medicinal Chemistry and Chemical Biology
Matthias Gehringer et al.
JOURNAL OF MEDICINAL CHEMISTRY (2019)
Selective and reversible modification of kinase cysteines with chlorofluoroacetamides
Naoya Shindo et al.
NATURE CHEMICAL BIOLOGY (2019)
Kinase inhibitors: the road ahead
Fleur M. Ferguson et al.
NATURE REVIEWS DRUG DISCOVERY (2018)
CD22: A Regulator of Innate and Adaptive B Cell Responses and Autoimmunity
Edward A. Clark et al.
FRONTIERS IN IMMUNOLOGY (2018)
A Perspective on the Kinetics of Covalent and Irreversible Inhibition
John M. Strelow
SLAS DISCOVERY (2017)
Acalabrutinib (ACP-196): A Covalent Bruton Tyrosine Kinase Inhibitor with a Differentiated Selectivity and In Vivo Potency Profile
Tjeerd Barf et al.
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2017)
Ability of Bruton's Tyrosine Kinase Inhibitors to Sequester Y551 and Prevent Phosphorylation Determines Potency for Inhibition of Fc Receptor but not B-Cell Receptor Signaling
Andrew T. Bender et al.
MOLECULAR PHARMACOLOGY (2017)
The target landscape of clinical kinase drugs
Susan Klaeger et al.
SCIENCE (2017)
Metabolically Labile Fumarate Esters Impart Kinetic Selectivity to Irreversible Inhibitors
Balyn W. Zaro et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2016)
Transcription factors of the alternative NF-κB pathway are required for germinal center B-cell development
Nilushi S. De Silva et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2016)
Selective JAK3 Inhibitors with a Covalent Reversible Binding Mode Targeting a New Induced Fit Binding Pocket
Michael Forster et al.
CELL CHEMICAL BIOLOGY (2016)
Covalent inhibitors in drug discovery: from accidental discoveries to avoided liabilities and designed therapies
Renato A. Bauer
DRUG DISCOVERY TODAY (2015)
Characterization of ibrutinib-sensitive and -resistant mantle lymphoma cells
Jiao Ma et al.
BRITISH JOURNAL OF HAEMATOLOGY (2014)
A road map to evaluate the proteome-wide selectivity of covalent kinase inhibitors
Bryan R. Lannine et al.
NATURE CHEMICAL BIOLOGY (2014)
Mechanisms and consequences of constitutive NF-κB activation in B-cell lymphoid malignancies
D. Nagel et al.
ONCOGENE (2014)
Enhanced activation of an amino-terminally truncated isoform of the voltage-gated proton channel HVCN1 enriched in malignant B cells
Elayne Hondares et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2014)
Electrophilic Fragment-Based Design of Reversible Covalent Kinase Inhibitors
Rand M. Miller et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2013)
A guide to picking the most selective kinase inhibitor tool compounds for pharmacological validation of drug targets
Joost C. M. Uitdehaag et al.
BRITISH JOURNAL OF PHARMACOLOGY (2012)
Reversible targeting of noncatalytic cysteines with chemically tuned electrophiles
Iana M. Serafimova et al.
NATURE CHEMICAL BIOLOGY (2012)
Activation of the glutaredoxin-1 gene by nuclear factor κB enhances signaling
Scott W. Aesif et al.
FREE RADICAL BIOLOGY AND MEDICINE (2011)
HVCN1 modulates BCR signal strength via regulation of BCR-dependent generation of reactive oxygen species
Melania Capasso et al.
NATURE IMMUNOLOGY (2010)
PI3 Kinase Signals BCR-Dependent Mature B Cell Survival
Lakshmi Srinivasan et al.
CELL (2009)
Optimal Sox-based fluorescent chemosensor design for serine/threonine protein kinases
Melissa D. Shults et al.
ANALYTICAL BIOCHEMISTRY (2006)
Bcl10 activates the NF-κB pathway through ubiquitination of NEMO
HL Zhou et al.
NATURE (2004)
Activity-based protein profiling in vivo using a copper(I)-catalyzed azide-alkyne [3+2] cycloaddition
AE Speers et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2003)
TRANSFAC (R): transcriptional regulation, from patterns to profiles
V Matys et al.
NUCLEIC ACIDS RESEARCH (2003)
分享论文
