相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。PROTACs and Other Chemical Protein Degradation Technologies for the Treatment of Neurodegenerative Disorders
Shusuke Tomoshige et al.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2021)
General and Robust Chemoenzymatic Method for Glycan-Mediated Site-Specific Labeling and Conjugation of Antibodies: Facile Synthesis of Homogeneous Antibody-Drug Conjugates
Xiao Zhang et al.
ACS CHEMICAL BIOLOGY (2021)
Development of Antibody-Based PROTACs for the Degradation of the Cell-Surface Immune Checkpoint Protein PD-L1
Adam D. Cotton et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2021)
Proteolysis-targeting chimera against BCL-XL destroys tumor-infiltrating regulatory T cells
Ryan Kolb et al.
NATURE COMMUNICATIONS (2021)
Development of Triantennary N-Acetylgalactosamine Conjugates as Degraders for Extracellular Proteins
Yaxian Zhou et al.
ACS CENTRAL SCIENCE (2021)
LYTACs that engage the asialoglycoprotein receptor for targeted protein degradation
Green Ahn et al.
NATURE CHEMICAL BIOLOGY (2021)
FROM THE ANALYST'S COUCH The oncology market for antibody-drug conjugates
Carolina do Pazo et al.
NATURE REVIEWS DRUG DISCOVERY (2021)
One-Pot Conversion of Free Sialoglycans to Functionalized Glycan Oxazolines and Efficient Synthesis of Homogeneous Antibody-Drug Conjugates through Site-Specific Chemoenzymatic Glycan Remodeling
Chong Ou et al.
BIOCONJUGATE CHEMISTRY (2021)
Bifunctional small molecules that mediate the degradation of extracellular proteins
David F. Caianiello et al.
NATURE CHEMICAL BIOLOGY (2021)
Chemoenzymatic glycan-selective remodeling of a therapeutic lysosomal enzyme with high-affinity M6P-glycan ligands. Enzyme substrate specificity is the name of the game
Xiao Zhang et al.
CHEMICAL SCIENCE (2021)
Degradation from the outside in: Targeting extracellular and membrane proteins for degradation through the endolysosomal pathway
Green Ahn et al.
CELL CHEMICAL BIOLOGY (2021)
Targeting of EGFR by a combination of antibodies mediates unconventional EGFR trafficking and degradation
Sylwia Jones et al.
SCIENTIFIC REPORTS (2020)
Lysosome-targeting chimaeras for degradation of extracellular proteins
Steven M. Banik et al.
NATURE (2020)
Glycoengineering of Antibodies for Modulating Functions
Lai-Xi Wang et al.
ANNUAL REVIEW OF BIOCHEMISTRY, VOL 88 (2019)
Targeted protein degradation: expanding the toolbox
Matthieu Schapira et al.
NATURE REVIEWS DRUG DISCOVERY (2019)
The PROTAC technology in drug development
Yutian Zou et al.
CELL BIOCHEMISTRY AND FUNCTION (2019)
One-pot enzymatic glycan remodeling of a therapeutic monoclonal antibody by endoglycosidase S (Endo-S) from Streptococcus pyogenes
Xin Tong et al.
BIOORGANIC & MEDICINAL CHEMISTRY (2018)
Development of a Novel B-Cell Lymphoma 6 (BCL6) PROTAC To Provide Insight into Small Molecule Targeting of BCL6
William McCoull et al.
ACS CHEMICAL BIOLOGY (2018)
Site-selective chemoenzymatic glycoengineering of Fab and Fc glycans of a therapeutic antibody
John P. Giddens et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2018)
Strategies and challenges for the next generation of antibody drug conjugates
Alain Beck et al.
NATURE REVIEWS DRUG DISCOVERY (2017)
Modulating IgG effector function by Fc glycan engineering
Tiezheng Li et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2017)
Targeted Protein Degradation: from Chemical Biology to Drug Discovery
Philipp M. Cromm et al.
CELL CHEMICAL BIOLOGY (2017)
Chemoenzymatic Synthesis of a Phosphorylated Glycoprotein
Pragya Priyanka et al.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2016)
Glycosynthase Mutants of Endoglycosidase S2 Show Potent Transglycosylation Activity and Remarkably Relaxed Substrate Specificity for Antibody Glycosylation Remodeling
Tiezheng Li et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2016)
Endo-F3 Glycosynthase Mutants Enable Chemoenzymatic Synthesis of Core-fucosylated Triantennary Complex Type Glycopeptides and Glycoproteins
John P. Giddens et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2016)
Chemoenzymatic Synthesis and Receptor Binding of Mannose-6-Phosphate (M6P)-Containing Glycoprotein Ligands Reveal Unusual Structural Requirements for M6P Receptor Recognition
Takahiro Yamaguchi et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2016)
Hijacking the E3 Ubiquitin Ligase Cereblon to Efficiently Target BRD4
Jing Lu et al.
CHEMISTRY & BIOLOGY (2015)
Catalytic in vivo protein knockdown by small-molecule PROTACs
Daniel P. Bondeson et al.
NATURE CHEMICAL BIOLOGY (2015)
Phthalimide conjugation as a strategy for in vivo target protein degradation
Georg E. Winter et al.
SCIENCE (2015)
Antibody- Drug Conjugates: An Emerging Concept in Cancer Therapy
Ravi V. J. Chari et al.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2014)
Design of a PROTAC that antagonizes and destroys the cancer-forming X-protein of the hepatitis B virus
Kristopher Montrose et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2014)
EndoS2 is a unique and conserved enzyme of serotype M49 group A Streptococcus that hydrolyses N-linked glycans on IgG and α1-acid glycoprotein
Jonathan Sjogren et al.
BIOCHEMICAL JOURNAL (2013)
Endocytosis and autophagy: Shared machinery for degradation
Christopher A. Lamb et al.
BIOESSAYS (2013)
Chemoenzymatic Glycoengineering of Intact IgG Antibodies for Gain of Functions
Wei Huang et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2012)
Fast analysis of recombinant monoclonal antibodies using IdeS proteolytic digestion and electrospray mass spectrometry
Guillaume Chevreux et al.
ANALYTICAL BIOCHEMISTRY (2011)
Combination antibody treatment down-regulates epidermal growth factor receptor by inhibiting endosomal recycling
Jamie B. Spangler et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)
Efficient Synthesis of Sugar Oxazolines from Unprotected N-Acetyl-2-amino Sugars by Using Chloroformamidinium Reagent in Water
Masato Noguchi et al.
JOURNAL OF ORGANIC CHEMISTRY (2009)
Cetuximab-induced anaphylaxis and IgE specific for galactose-α-1,3-galactose
Christine H. Chung et al.
NEW ENGLAND JOURNAL OF MEDICINE (2008)
Structural characterization of N-linked oligosaccharides on monoclonal antibody cetuximab by the combination of orthogonal matrix-assisted laser desorption/ionization hybrid quadrupole-quadrupole time-of-flight tandem mass spectrometry and sequential enzymatic digestion
Jun Qian et al.
ANALYTICAL BIOCHEMISTRY (2007)
Protacs: Chimeric molecules that target proteins to the Skp1-Cullin-F box complex for ubiquitination and degradation
KM Sakamoto et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2001)
EndoS, a novel secreted protein from Streptococcus pyogenes with endoglycosidase activity on human IgG
M Collin et al.
EMBO JOURNAL (2001)