期刊
BMJ CASE REPORTS
卷 15, 期 2, 页码 -出版社
BMJ PUBLISHING GROUP
DOI: 10.1136/bcr-2021-244030
关键词
retina; haematology (incl blood transfusion)
Bilateral retinal detachment is a rare ocular manifestation of TTP. Prompt treatment with PLEX, prednisone, rituximab, and caplacizumab can lead to significant vision recovery.
Ocular manifestations of thrombotic thrombocytopenic purpura (TTP) are uncommon, and bilateral retinal detachment is a rare presentation of TTP. We report a rare case of bilateral retinal detachment from underlying TTP in a patient presenting with vision loss. A 56-year-old man presented with a 4-day history of bilateral vision loss. Bilateral serous retinal detachment was confirmed using dilated ophthalmoscope examination. Laboratory results were significant for severe thrombocytopenia, peripheral smear revealed numerous schistocytes and ADAMTS13 activity of less than 1%. The patient was treated with plasma exchange (PLEX), prednisone, rituximab and caplacizumab. This case report highlights that prompt treatment of TTP with PLEX, prednisone, rituximab and caplacizumab could result in significant vision recovery.
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