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Acute respiratory distress syndrome in COVID-19: possible mechanisms and therapeutic management

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PNEUMONIA
卷 13, 期 1, 页码 -

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BMC
DOI: 10.1186/s41479-021-00092-9

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COVID-19; Acute respiratory distress syndrome; SARS-CoV-2; Pandemics; ARDS

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The COVID-19 pandemic is a serious issue in the new era, with a focus on controlling lung diseases such as ARDS and lung failure. Ongoing research is crucial, with current emphasis on managing COVID-19 patients and evaluating treatment strategies for ARDS induced by COVID-19.
COVID-19 pandemic is a serious concern in the new era. Acute respiratory distress syndrome (ARDS), and lung failure are the main lung diseases in COVID-19 patients. Even though COVID-19 vaccinations are available now, there is still an urgent need to find potential treatments to ease the effects of COVID-19 on already sick patients. Multiple experimental drugs have been approved by the FDA with unknown efficacy and possible adverse effects. Probably the increasing number of studies worldwide examining the potential COVID-19 related therapies will help to identification of effective ARDS treatment. In this review article, we first provide a summary on immunopathology of ARDS next we will give an overview of management of patients with COVID-19 requiring intensive care unit (ICU), while focusing on the current treatment strategies being evaluated in the clinical trials in COVID-19-induced ARDS patients.

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