期刊
INTERNATIONAL JOURNAL OF OBESITY
卷 40, 期 6, 页码 998-1004出版社
NATURE PUBLISHING GROUP
DOI: 10.1038/ijo.2016.21
关键词
-
资金
- NIH [R01 HL096782-01A2]
- King Charitable Foundation Trust
- Cain Foundation
- Texas Health Presbyterian Hospital Dallas
BACKGROUND: The effects of moderate weight loss on operational lung volumes during exercise and the oxygen (O-2) cost of breathing are unknown in obese women but could have important implications regarding exercise endurance. METHODS: In 29 obese women (33 +/- 8 years, 97 +/- 14 kg, body mass index: 36 +/- 4 kg m(-2), body fat: 45.6 +/- 4.5%; means +/- s.d.), body composition, fat distribution (by magnetic resonance imaging), pulmonary function, operational lung volumes during exercise and the O-2 cost of breathing during eucapnic voluntary hyperpnea ((V)over dot O-2) vs ((V) over dot(E)) slope) were studied before and after a 12-week diet and resistance exercise weight loss program. RESULTS: Participants lost 7.5 +/- 3.1 kg or approximate to 8% of body weight (P<0.001), but fat distribution remained unchanged. After weight loss, lung volume subdivisions at rest were increased (P<0.05) and were moderately associated (P<0.05) with changes in weight. End-expiratory lung volume (percentage of total lung capacity) increased at rest and during constant load exercise (P<0.05). O-2 cost of breathing was reduced by 16% (2.52 +/- 1.02-2.11 +/- 0.72 ml l(-1); P = 0.003). As a result, O-2 uptake of the respiratory muscles ((V)over dotO(2Resp)), estimated as the product of O-2 cost of breathing and exercise ((V) over dot(E)) during cycling at 60 W, was significantly reduced by 27 +/- 31 ml (P<0.001), accounting for 46% of the reduction in total body ((V)over dot O-2) during cycling at 60 W. CONCLUSIONS: Moderate weight loss yields important improvements in respiratory function at rest and during submaximal exercise in otherwise healthy obese women. These changes in breathing load could have positive effects on the exercise endurance and adherence to physical activity.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据