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Draft Genome Sequences of 12 Panton-Valentine Leucocidin-Positive and Multidrug-Resistant Methicillin-Resistant Staphylococcus aureus Strains Isolated from an Intensive Care Unit in Pakistan

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AMER SOC MICROBIOLOGY
DOI: 10.1128/MRA.01190-21

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  1. National Center for Toxicological Research
  2. U.S. Food and Drug Administration [E0771001]

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This study sequenced and annotated clinical MRSA isolates from hospitals in Pakistan to investigate genetic markers associated with antimicrobial resistance, virulence, and biofilm formation.
Methicillin-resistant Staphylococcus aureus (MRSA) is a pathogenic bacterium responsible for difficult-to-treat staphylococcal infections due to multidrug resistance. Twelve Panton-Valentine leucocidin (PVL)-positive and multidrug-resistant clinical MRSA isolates from hospitals in Pakistan were sequenced and annotated to investigate genetic markers associated with antimicrobial resistance, virulence, and biofilm formation.

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