期刊
QUARTERLY JOURNAL OF ECONOMICS
卷 137, 期 2, 页码 1139-1179出版社
OXFORD UNIV PRESS INC
DOI: 10.1093/qje/qjab043
关键词
-
类别
资金
- NIDA [P50DA046351]
- CDC [R01CE02999]
- Institute for Scholarship in the Liberal Arts at the University of Notre Dame
This article examines the role of the introduction and marketing of OxyContin in 1996 as a potential leading cause of the opioid crisis. Through analyzing cross-state variation in exposure to OxyContin's introduction, it is found that triplicate states had lower OxyContin distribution and slower growth in overdose deaths, indicating that the introduction and marketing of OxyContin explain a substantial share of overdose deaths over the past two decades.
Overdose deaths involving opioids have increased dramatically since the 1990s, leading to the worst drug overdose epidemic in U.S. history, but there is limited empirical evidence about the initial causes. In this article, we examine the role of the 1996 introduction and marketing of OxyContin as a potential leading cause of the opioid crisis. We leverage cross-state variation in exposure to OxyContin's introduction due to a state policy that substantially limited the drug's early entry and marketing in select states. Recently unsealed court documents involving Purdue Pharma show that state-based triplicate prescription programs posed a major obstacle to sales of OxyContin and suggest that less marketing was targeted to states with these programs. We find that OxyContin distribution was more than 50% lower in triplicate states in the years after the drug's launch. Although triplicate states had higher rates of overdose deaths prior to 1996, this relationship flipped shortly after the launch and triplicate states saw substantially slower growth in overdose deaths, continuing even 20 years after OxyContin's introduction. Our results show that the introduction and marketing of OxyContin explain a substantial share of overdose deaths over the past two decades. JEL Codes: I12, I18.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据