期刊
OPHTHALMOLOGY AND THERAPY
卷 11, 期 1, 页码 113-123出版社
SPRINGER INT PUBL AG
DOI: 10.1007/s40123-021-00408-4
关键词
Capsulorhexis; Cataract surgery; Early-onset posterior capsule opacification; Intraocular lens; Risk factors
资金
- National Natural Science Foundation of China [81770905, 81873675, 81700820]
- Pearl River Nova Program of Guangzhou [201806010167]
- Construction Project of High-Level Hospitals in Guangdong Province [303020102]
This study evaluated the incidence, severity, and risk factors of early-onset PCO following cataract surgery, finding that larger capsulorhexis and a history of PPV surgery contribute to the occurrence of PCO.
Introduction To evaluate the incidence, severity, and risk factors of early-onset posterior capsule opacification (PCO) following uneventful phacoemulsification and intraocular lens (IOL) implantation. Methods Patients with cataracts who underwent phacoemulsification and IOL implantation surgery for 3 months from September 2019 to April 2020 were enrolled. All the subjects completed a comprehensive ocular examination. Retroillumination images of the posterior capsule were obtained using a slit lamp with imaging system, and PCO was graded by two ophthalmologists. Univariate and multivariate logistic regression analyses were performed to assess the risk factors for PCO. Results A total of 1039 subjects were enrolled, with mean age 66.68 +/- 11.43 years and 42.06% were male. The incidence of early-onset PCO in the 3 months after cataract surgery was 29.93%, and PCO of grade 3 and grade 4 was present in 31 patients (2.98%). Patients with complicated cataract had a higher incidence of PCO than age-related cataract, especially for patients with previous pars plana vitrectomy (PPV) surgery (P < 0.001). Moreover, the incidence of PCO increased with the deficiency of capsulorhexis-IOL overlap (P < 0.001). Multivariate logistic regression also showed that previous PPV surgery (OR 2.664, P = 0.003) and incomplete capsulorhexis-IOL overlap were risk factors for PCO (180-360 degrees overlap: OR 2.058, P < 0.001; < 180 degrees overlap: OR 5.403, P < 0.001). Conclusions Larger capsulorhexis and PPV surgery history contribute to the occurrence of early-onset PCO, indicating that primary posterior continuous curvilinear capsulorhexis can be considered during cataract surgery for patients with PPV history.
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