期刊
INTERNATIONAL JOURNAL OF IMMUNOPATHOLOGY AND PHARMACOLOGY
卷 29, 期 4, 页码 583-594出版社
SAGE PUBLICATIONS INC
DOI: 10.1177/0394632015623793
关键词
inflammatory markers; major depressive disorder; suicidal attempts
Major depressive disorder is a chronic and invalidating psychiatric illness and is associated with a greater risk of suicidal behaviors. In recent decades many data have supported a biological link between depressive states and inflammation. Pro- inflammatory cytokines have been found to rise, first of all TNF-alpha and IL-6. Suicidal behaviors have been consistently associated with increased levels of IL-6 and decreased levels of IL-2. The aim of this review is to investigate the relationship between inflammatory markers in depressed patients with or without suicidal attempts compared to healthy controls.
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