期刊
CHILDREN-BASEL
卷 9, 期 2, 页码 -出版社
MDPI
DOI: 10.3390/children9020214
关键词
generalized lymphadenopathy; lymphoproliferative disease; colon polyp; Progressive Transformation of Germinal Centers
类别
资金
- National Center for Advancing Translational Sciences [KL2 TR002015]
- Four Diamonds Pediatric Cancer Research Center at Penn State College of Medicine
This article reports a rare case of lymphadenopathy in a child, emphasizing the importance of long-term follow-up and tailoring the diagnostic work-up and management based on new signs and symptoms.
Background: Enlarged lymph nodes are a common complaint in a Pediatrician's office. Diagnosis of reactive lymphadenopathy secondary to infectious, inflammatory, immune dysregulation calls for clinical investigation, including a thorough history, physical exam, imaging, and less often, a biopsy of the lymph node. Here we discuss a rare presentation of extensive generalized, chronic, waxing, and waning lymphadenopathy diagnosed as Progressive Transformation of Germinal Centers (PTGC) and the course of illness over eight years follow up period. Discussion: Progressive Transformation of Germinal Centers (PTGC) is considered a benign condition, but extensive recurrent generalized lymphadenopathy in a very young child has not been reported before. This case demonstrates the importance of long-term follow-up and tailoring the diagnostic work-up and management based on new signs and symptoms. Here we focus on the clinical considerations and management of complex presentation of a common clinical finding.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据