☆ 4.6 Review

Current Knowledge of MicroRNAs (miRNAs) in Acute Coronary Syndrome (ACS): ST-Elevation Myocardial Infarction (STEMI)

LIFE-BASEL (2021)

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Article Medicine, General & Internal

Serum microRNA-185 Levels and Myocardial Injury in Patients with Acute ST-segment Elevation Myocardial Infarction

Jeong Rang Park et al.

Summary: The changes in miR-185 levels in patients with ST-segment elevation myocardial infarction (STEMI) are related to myocardial healing and remodeling. MiR-185 levels at discharge are correlated with troponin-I, CK-MB, and CK-MB area under the curve levels. High miR-185 levels are associated with high wall motion score index, low ejection fraction, and high B-type natriuretic peptide level at one month after STEMI.

INTERNAL MEDICINE (2022)

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Article Cardiac & Cardiovascular Systems

Circulating miRNAs Related to Long-term Adverse Cardiovascular Events in STEMI Patients: A Nested Case-Control Study

Xinying Yang et al.

Summary: This study found that circulating miR-26a-5p, miR-21-5p, and miR-191-5p levels were lower in patients who experienced major adverse cardiovascular events after acute myocardial infarction compared to those who did not. Multivariate conditional logistic regression analysis showed that these miRNAs were significantly inversely associated with incident primary composite outcomes. Combining these miRNAs with B-type natriuretic peptide improved risk scores recommended in the current guidelines.

CANADIAN JOURNAL OF CARDIOLOGY (2021)

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Article Biotechnology & Applied Microbiology

RNA-seq identifies circulating miRNAs as potential biomarkers for plaque rupture in patients with ST-segment elevation myocardial infarction

Jiannan Li et al.

Summary: The study identified that miR-744-3p, miR-324-3p, and miR-330-3p were significantly upregulated in patients with plaque rupture (PR) compared to those with plaque erosion (PE). The combination of these three miRNAs had clinical utility in distinguishing between PR and PE, with an area under the receiver operating characteristic curve of 0.764 and 0.768 in training and test sets, respectively. These circulating microRNAs could serve as diagnostic markers for distinguishing plaque phenotype in ST-elevation myocardial infarction patients.

GENOMICS (2021)

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Review Cell Biology

The Role of Exosomes and Exosomal MicroRNA in Cardiovascular Disease

Dongdong Zheng et al.

Summary: Exosomes are small vesicles secreted by most cells in the body, carrying various molecules including miRNA which play crucial roles in post-transcriptional regulation and cardiovascular health. Research indicates that exosomal miRNAs are widely involved in the occurrence and development of cardiovascular diseases.

FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY (2021)

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Article Cardiac & Cardiovascular Systems

Diagnostic value of circulating microRNAs compared to high-sensitivity troponin T for the detection of non-ST-segment elevation myocardial infarction

Moritz Biener et al.

Summary: This study evaluated the diagnostic value of 11 microRNAs for NSTEMI, finding that a panel of three microRNAs could be associated with NSTEMI diagnosis, but did not improve diagnostic accuracy compared to the hs-cTnT reference standard.

EUROPEAN HEART JOURNAL-ACUTE CARDIOVASCULAR CARE (2021)

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Article Cardiac & Cardiovascular Systems

Vascular conditioning prevents adverse left ventricular remodelling after acute myocardial infarction: a randomised remote conditioning study

Ignatios Ikonomidis et al.

Summary: The study showed that remote ischemic conditioning can promote vascular adaptation, likely through upregulation of cardio-protective microRNAs, NOx production, and reduction of oxidative stress. After single-cycle inflation, PBR decreased, PWV reduced, miR-144 and NOx levels increased, and LVESV decreased.

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Circulating miR-21, miR-29a, and miR-126 are associated with premature death risk due to cancer and cardiovascular disease: the JACC Study

Hiroya Yamada et al.

Summary: This study found that high levels of circulating miR-21 and miR-29a were significantly associated with an increased risk of total death, cancer death, and CVD death, while individuals with low levels of circulating miR-126 were more likely to experience total death. This suggests that circulating miRNAs may serve as potential biomarkers for early detection of high-risk individuals.

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Mir-1, miR-122, miR-132, and miR-133 Are Related to Subclinical Aortic Atherosclerosis Associated with Metabolic Syndrome

Agne Satrauskiene et al.

Summary: Four miRs (miR-1, miR-133b, miR-133a, and miR-145) were negatively associated with arterial markers of subclinical atherosclerosis in subjects with metabolic syndrome. Combined, these miRs may have a more substantial diagnostic or prognostic value. Follow-up studies are needed to establish their clinical relevance.

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Review Biochemistry & Molecular Biology

MicroRNAs in Acute ST Elevation Myocardial Infarction-A New Tool for Diagnosis and Prognosis: Therapeutic Implications

Alina Ioana Scarlatescu et al.

Summary: MicroRNAs have emerged as promising tools in the field of cardiovascular diseases, with potential in diagnostic, prognostic, and therapeutic applications for patients with ST elevation myocardial infarction.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2021)

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Review Biochemistry & Molecular Biology

A Brief Review on the Biology and Effects of Cellular and Circulating microRNAs on Cardiac Remodeling after Infarction

Mihir Parikh et al.

Summary: Despite advancements in diagnostic and treatment modalities, myocardial infarction (MI) remains a major cause of morbidity and mortality. MicroRNAs (miRNAs) have been studied for their role in cellular signaling and cardiac conditions like MI, showing potential for future therapeutic developments in cardiovascular diseases.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2021)

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Article Cardiac & Cardiovascular Systems

Cardiac Troponin Thresholds and Kinetics to Differentiate Myocardial Injury and Myocardial Infarction

Ryan Wereski et al.

Summary: The study found that cardiac troponin concentrations at presentation are insufficient to distinguish type 1 myocardial infarction from other causes of myocardial injury or infarction. The change in troponin concentration plays a more important role in the diagnosis of myocardial infarction than the absolute troponin value.

CIRCULATION (2021)

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Article Pathology

miR-3113-5p, miR-223-3p, miR-133a-3p, and miR-499a-5p are sensitive biomarkers to diagnose sudden cardiac death

Fengping Yan et al.

Summary: Sudden cardiac death (SCD) is a major health threat and diagnostic challenges persist, especially in cases without positive autopsy findings. In this study, specific cardio-miRNAs were investigated as potential biomarkers for SCD diagnosis. The results showed that four cardio-miRNAs were significantly up-regulated in SCD samples, suggesting their potential as independent diagnostic biomarkers, with a combination of two miRNAs aiding in discriminating detailed causes of SCD.

DIAGNOSTIC PATHOLOGY (2021)

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Review Medicine, General & Internal

Exploring diagnostic and prognostic predictive values of microRNAs for acute myocardial infarction A PRISMA-compliant systematic review and meta-analysis

Gien-Kuo Lee et al.

Summary: A systematic review revealed that circulating miRNAs (miR-1, miR-133, miR-208, and miR-499) showed diagnostic values in acute myocardial infarction (AMI) with good sensitivity and specificity.

MEDICINE (2021)

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A Novel Circulating MicroRNA for the Detection of Acute Myocarditis

Rafael Blanco-Dominguez et al.

Summary: By identifying a novel microRNA mmu-miR-721 in mice and its human homologue hsa-miR-Chr8:96 in patients with myocarditis, researchers found that this microRNA could effectively distinguish patients with myocarditis from those with myocardial infarction, providing a potential non-invasive diagnostic approach.

NEW ENGLAND JOURNAL OF MEDICINE (2021)

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A Four-MicroRNA Panel in Peripheral Blood Identified as an Early Biomarker to Diagnose Acute Myocardial Infarction

Liang Chen et al.

Summary: The study demonstrated that the expression levels of circulating miR-1291, miR-217, miR-455-3p, and miR-566 were significantly lower in patients with AMI, showing potential as early diagnostic biomarkers for AMI when combined.

FRONTIERS IN PHYSIOLOGY (2021)

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Review Genetics & Heredity

Comparison of the Clinical Value of miRNAs and Conventional Biomarkers in AMI: A Systematic Review

Baofu Wang et al.

Summary: This study demonstrates that certain miRNAs reach peak time earlier than conventional biomarkers in acute myocardial infarction (AMI) and show a shorter time window, making them more promising biomarkers. Within 4 hours of onset of symptoms, miRNAs exhibit the most potential as biomarkers. Combining miRNAs or miRNAs with traditional biomarkers can improve the accuracy of early AMI diagnosis.

FRONTIERS IN GENETICS (2021)

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Review Medicine, General & Internal

Reducing Cardiac Injury during ST-Elevation Myocardial Infarction: A Reasoned Approach to a Multitarget Therapeutic Strategy

Alessandro Bellis et al.

Summary: Reducing myocardial-ischemia reperfusion injury (MIRI) is crucial for improving prognosis in ST elevation myocardial infarction (STEMI) patients. While single interventions have shown benefits, a multitarget therapeutic strategy is needed to effectively reduce mortality.

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Circulating Extracellular miRNA Analysis in Patients with Stable CAD and Acute Coronary Syndromes

Andrey Zhelankin et al.

Summary: This study found that miR-21-5p and miR-146a-5p were significantly elevated in ACS patients, while miR-17-5p was decreased in ACS and stable CAD patients. Differences in the plasma levels of these miRNAs were not found between patients with positive or negative troponin, nor between STEMI and NSTEMI within the ACS patient group.

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MiR-126-3p and MiR-223-3p as Biomarkers for Prediction of Thrombotic Risk in Patients with Acute Myocardial Infarction and Primary Angioplasty

Milan Hromadka et al.

Summary: This study indicated that miR-223-3p and miR-126-3p are promising independent predictors of thrombotic events post-AMI, with miR-223-3p levels significantly associated with ischemic endpoints and the miR-126-3p to miR-223-3p ratio being related to risk reduction.

JOURNAL OF PERSONALIZED MEDICINE (2021)

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Article Cardiac & Cardiovascular Systems

MicroRNA-200a represses myocardial infarction-related cell death and inflammation by targeting the Keap1/Nrf2 and β-catenin pathways

Yi Ma et al.

Summary: The study demonstrated that miR-200a plays a protective role in MI treatment by regulating the Keap1/Nrf2 and beta-catenin signaling pathways to protect cardiomyocytes from death.

HELLENIC JOURNAL OF CARDIOLOGY (2021)

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Review Cardiac & Cardiovascular Systems

Circulating biomarkers as predictors of left ventricular remodeling after myocardial infarction

Michal Wegiel et al.

Summary: The study analyzed data on circulating biomarkers of remodeling after myocardial infarction from 2005 to 2020, covering 53 articles and 160 relationships between biomarkers and remodeling. The results showed that while a relatively large number of biomarkers were tested, selecting one ideal marker remains a challenge, and a combination of biomarkers from different groups may be more suitable for predicting remodeling.

POSTEPY W KARDIOLOGII INTERWENCYJNEJ (2021)

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Review Cardiac & Cardiovascular Systems

Role of Selected miRNAs as Diagnostic and Prognostic Biomarkers in Cardiovascular Diseases, Including Coronary Artery Disease, Myocardial Infarction and Atherosclerosis

Rashid Mir et al.

Summary: miRNAs play a crucial role in cardiovascular physiology development and pathophysiology of heart diseases, serving as important factors in the diagnosis and prevention of these diseases. The high stability of miRNAs in body fluids makes them promising candidates as powerful tools for the diagnosis of cardiovascular diseases.

JOURNAL OF CARDIOVASCULAR DEVELOPMENT AND DISEASE (2021)

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Review Health Care Sciences & Services

High-sensitivity troponin assays for early rule-out of acute myocardial infarction in people with acute chest pain: a systematic review and economic evaluation

Marie Westwood et al.

Summary: The study found that high-sensitivity cardiac troponin testing may be more cost-effective than standard testing, especially for early exclusion of acute myocardial infarction. Strategies with high-sensitivity troponin testing could reduce length of stay and improve efficiency in the diagnosis of acute chest pain patients.

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Article Developmental Biology

MiRNA-26a inhibits myocardial infarction-induced apoptosis by targeting PTEN via JAK/STAT pathways

Jianzhong Wang et al.

Summary: MiR-26a expression is downregulated in MI cardiac tissues under H2O2 stress, but it can still protect against cell death by modulating the PI3K/Akt and JAK/STAT signal transduction pathways through direct targeting of PTEN.

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MicroRNA-33 and SIRT1 influence the coronary thrombus burden in hyperglycemic STEMI patients

Nunzia D'Onofrio et al.

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MicroRNA-9 overexpression suppresses vulnerable atherosclerotic plaque and enhances vascular remodeling through negative regulation of the p38MAPK pathway via OLR1 in acute coronary syndrome

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Kinetics Analysis of Circulating MicroRNAs Unveils Markers of Failed Myocardial Reperfusion

Jose Coelho-Lima et al.

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Circulating biomarkers for long-term cardiovascular risk stratification in apparently healthy individuals from the MONICA 10 cohort

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EUROPEAN JOURNAL OF PREVENTIVE CARDIOLOGY (2020)

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Salim S. Virani et al.

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Differentially expressed microRNA profiles in exosomes from vascular smooth muscle cells associated with coronary artery calcification

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Branislav Kura et al.

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miR-26a attenuates cardiac apoptosis and fibrosis by targeting ataxia-telangiectasia mutated in myocardial infarction

Ming-Hsien Chiang et al.

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Dinesh Kumar et al.

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Myocardial infarction-induced microRNA-enriched exosomes contribute to cardiac Nrf2 dysregulation in chronic heart failure

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AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY (2018)

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MicroRNA-133a impairs perfusion recovery after hindlimb ischemia in diabetic mice

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BIOSCIENCE REPORTS (2018)

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MicroRNA-223 Regulates Cardiac Fibrosis After Myocardial Infarction by Targeting RASA1

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CELLULAR PHYSIOLOGY AND BIOCHEMISTRY (2018)

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Review Biochemistry & Molecular Biology

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FEBS LETTERS (2018)

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Article Cardiac & Cardiovascular Systems

MicroRNA-208a Correlates Apoptosis and Oxidative Stress Induced by H2O2 through Protein Tyrosine Kinase/Phosphatase Balance in Cardiomyocytes

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INTERNATIONAL HEART JOURNAL (2018)

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Article Biochemistry & Molecular Biology

Circulating MicroRNAs in Young Patients with Acute Coronary Syndrome

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INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2018)

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Relationship between circulating miRNA-30e and no-reflow phenomenon in STEMI patients undergoing primary coronary intervention

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SCANDINAVIAN JOURNAL OF CLINICAL & LABORATORY INVESTIGATION (2018)

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MicroRNA-21 prevents excessive inflammation and cardiac dysfunction after myocardial infarction through targeting KBTBD7

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CELL DEATH & DISEASE (2018)

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MiR-26a-5p regulates cardiac fibroblasts collagen expression by targeting ULK1

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SCIENTIFIC REPORTS (2018)

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Circulating miR-30a-5p as a prognostic biomarker of left ventricular dysfunction after acute myocardial infarction

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Protein Biomarkers of Cardiovascular Disease and Mortality in the Community

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JOURNAL OF THE AMERICAN HEART ASSOCIATION (2018)

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Review Cell Biology

Towards frailty biomarkers: Candidates from genes and pathways regulated in aging and age-related diseases

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AGEING RESEARCH REVIEWS (2018)

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Circulating miR-1254 predicts ventricular remodeling in patients with ST-Segment- Elevation Myocardial Infarction: A cardiovascular magnetic resonance study

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SCIENTIFIC REPORTS (2018)

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Article Cell Biology

MicroRNA miR-24-3p Reduces Apoptosis and Regulates Keap1-Nrf2 Pathway in Mouse Cardiomyocytes Responding to Ischemia/Reperfusion Injury

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OXIDATIVE MEDICINE AND CELLULAR LONGEVITY (2018)

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Large Differences in Small RNA Composition Between Human Biofluids

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Review Peripheral Vascular Disease

Noncoding RNAs in Cardiovascular Disease: Pathological Relevance and Emerging Role as Biomarkers and Therapeutics

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MicroRNAs in pathophysiology of acute myocardial infarction and cardiogenic shock

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Association of MIR-499a expression and seed region variant (rs3746444) with cardiovascular disease in Egyptian patients

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ACTA CARDIOLOGICA (2018)

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Review Cardiac & Cardiovascular Systems

Role of miRNAs on the Pathophysiology of Cardiovascular Diseases

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ARQUIVOS BRASILEIROS DE CARDIOLOGIA (2018)

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Circulating microRNAs strongly predict cardiovascular death in patients with coronary artery disease-results from the large AtheroGene study

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Platelet microRNA for predicting acute myocardial infarction

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JOURNAL OF THROMBOSIS AND THROMBOLYSIS (2017)

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miR-23a Regulates Cardiomyocyte Apoptosis by Targeting Manganese Superoxide Dismutase

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MOLECULES AND CELLS (2017)

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Circulating miR-155, miR-145 and let-7c as diagnostic biomarkers of the coronary artery disease

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SCIENTIFIC REPORTS (2017)

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Article Cell Biology

Potential Involvement of MiR-30e-3p in Myocardial Injury Induced by Coronary Microembolization via Autophagy Activation

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CELLULAR PHYSIOLOGY AND BIOCHEMISTRY (2017)

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Article Cardiac & Cardiovascular Systems

Failed Downregulation of Circulating MicroRNA-155 in the Early Phase after ST Elevation Myocardial Infarction Is Associated with Adverse Left Ventricular Remodeling

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CARDIOLOGY (2017)

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Article Cardiac & Cardiovascular Systems

miR-941 as a promising biomarker for acute coronary syndrome

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BMC CARDIOVASCULAR DISORDERS (2017)

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Review Cardiac & Cardiovascular Systems

Circulating Noncoding RNAs as Biomarkers of Cardiovascular Disease and Injury

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CIRCULATION RESEARCH (2017)

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Circulating MiR-19b-3p, MiR-134-5p and MiR-186-5p are Promising Novel Biomarkers for Early Diagnosis of Acute Myocardial Infarction

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Article Cardiac & Cardiovascular Systems

Circulating miR-122-5p/miR-133b Ratio Is a Specific Early Prognostic Biomarker in Acute Myocardial Infarction

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Article Cardiac & Cardiovascular Systems

Consequences of implementing a cardiac troponin assay with improved sensitivity at Swedish coronary care units: an analysis from the SWEDEHEART registry

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Article Cardiac & Cardiovascular Systems

miRNA-93-5p and other miRNAs as predictors of coronary artery disease and STEMI

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INTERNATIONAL JOURNAL OF CARDIOLOGY (2016)

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Review Cardiac & Cardiovascular Systems

Cardiac-specific miRNA in cardiogenesis, heart function, and cardiac pathology (with focus on myocardial infarction)

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JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY (2016)

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Review Cardiac & Cardiovascular Systems

MicroRNAs in Cardiovascular Disease

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JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY (2016)

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Decision-making microRNAs (miR-124,-133a/b,-34a and-134) in patients with occluded target vessel in acute coronary syndrome

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Stratification of ST-elevation myocardial infarction patients based on soluble CD4OL longitudinal changes

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TRANSLATIONAL RESEARCH (2016)

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Article Cardiac & Cardiovascular Systems

MicroRNA-155 aggravates ischemia-reperfusion injury by modulation of inflammatory cell recruitment and the respiratory oxidative burst

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BASIC RESEARCH IN CARDIOLOGY (2015)

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Article Cardiac & Cardiovascular Systems

Expression of circulating miR-486 and miR-150 in patients with acute myocardial infarction

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BMC CARDIOVASCULAR DISORDERS (2015)

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Article Cardiac & Cardiovascular Systems

Circulating MicroRNA-146a and MicroRNA-21 Predict Left Ventricular Remodeling after ST-Elevation Myocardial Infarction

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CARDIOLOGY (2015)

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Review Peripheral Vascular Disease

MicroRNA Biomarkers for Coronary Artery Disease?

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CURRENT ATHEROSCLEROSIS REPORTS (2015)

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Letter Cardiac & Cardiovascular Systems

Prognostic value of microRNAs in acute myocardial infarction: A systematic review and meta-analysis

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INTERNATIONAL JOURNAL OF CARDIOLOGY (2015)

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Article Cardiac & Cardiovascular Systems

Release kinetics of circulating miRNA-208a in the early phase of myocardial infarction

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MicroRNA-208a Dysregulates Apoptosis Genes Expression and Promotes Cardiomyocyte Apoptosis during Ischemia and Its Silencing Improves Cardiac Function after Myocardial Infarction

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MEDIATORS OF INFLAMMATION (2015)

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miRNA-197 and miRNA-223 Predict Cardiovascular Death in a Cohort of Patients with Symptomatic Coronary Artery Disease

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Prediction of long-term outcome after acute myocardial infarction using circulating miR-145

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Article Medicine, Research & Experimental

Clinical impact of circulating miR-26a, miR-191, and miR-208b in plasma of patients with acute myocardial infarction

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Article Cardiac & Cardiovascular Systems

A signature of circulating microRNAs differentiates takotsubo cardiomyopathy from acute myocardial infarction

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EUROPEAN HEART JOURNAL (2014)

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Article Biochemistry & Molecular Biology

Circulating miR-208b and miR-34a Are Associated with Left Ventricular Remodeling after Acute Myocardial Infarction

Pin Lv et al.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2014)

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Article Cell Biology

Predictive value of circulating miR-328 and miR-134 for acute myocardial infarction

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MOLECULAR AND CELLULAR BIOCHEMISTRY (2014)

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Article Multidisciplinary Sciences

MicroRNA-208a Increases Myocardial Fibrosis via Endoglin in Volume Overloading Heart

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PLOS ONE (2014)

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Article Cardiac & Cardiovascular Systems

An emerging role for the miR-26 family in cardiovascular disease

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TRENDS IN CARDIOVASCULAR MEDICINE (2014)

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Review Immunology

MicroRNA-146a: a dominant, negative regulator of the innate immune response

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FRONTIERS IN IMMUNOLOGY (2014)

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Article Cardiac & Cardiovascular Systems

Circulating cardio-enriched microRNAs are associated with long-term prognosis following myocardial infarction

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BMC CARDIOVASCULAR DISORDERS (2013)

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Article Cardiac & Cardiovascular Systems

Mechanical stretch via transforming growth factor-β1 activates microRNA208a to regulate endoglin expression in cultured rat cardiac myoblasts

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EUROPEAN JOURNAL OF HEART FAILURE (2013)

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Article Cardiac & Cardiovascular Systems

Release Kinetics of Circulating Muscle-Enriched MicroRNAs in Patients Undergoing Transcoronary Ablation of Septal Hypertrophy

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JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY (2013)

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Article Multidisciplinary Sciences

Correction: A Panel of 4 microRNAs Facilitates the Prediction of Left Ventricular Contractility after Acute Myocardial Infarction

Yvan Devaux et al.

PLoS One (2013)

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Article Cardiac & Cardiovascular Systems

Relation of circulating MicroRNA-133a concentrations with myocardial damage and clinical prognosis in ST-elevation myocardial infarction

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AMERICAN HEART JOURNAL (2012)

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Article Biochemistry & Molecular Biology

A subset of circulating microRNAs are predictive for cardiac death after discharge for acute myocardial infarction

Sen Matsumoto et al.

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2012)

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Article Cardiac & Cardiovascular Systems

MicroRNA-101 Inhibited Postinfarct Cardiac Fibrosis and Improved Left Ventricular Compliance via the FBJ Osteosarcoma Oncogene/Transforming Growth Factor-β1 Pathway

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Use of Circulating MicroRNAs to Diagnose Acute Myocardial Infarction

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CLINICAL CHEMISTRY (2012)

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Early assessment of acute coronary syndromes in the emergency department: the potential diagnostic value of circulating microRNAs

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EMBO MOLECULAR MEDICINE (2012)

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Article Biochemistry & Molecular Biology

Human Circulating MicroRNA-1 and MicroRNA-126 as Potential Novel Indicators for Acute Myocardial Infarction

Guangwen Long et al.

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MicroRNA 21 Inhibits Left Ventricular Remodeling in the Early Phase of Rat Model with Ischemia-reperfusion Injury by Suppressing Cell Apoptosis

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INTERNATIONAL JOURNAL OF MEDICAL SCIENCES (2012)

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Article Cardiac & Cardiovascular Systems

A translational study of urine miRNAs in acute myocardial infarction

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JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY (2012)

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Article Cardiac & Cardiovascular Systems

MicroRNA signatures in total peripheral blood as novel biomarkers for acute myocardial infarction

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BASIC RESEARCH IN CARDIOLOGY (2011)

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Article Cardiac & Cardiovascular Systems

Cardiospecific microRNA Plasma Levels Correlate with Troponin and Cardiac Function in Patients with ST Elevation Myocardial Infarction, Are Selectively Dependent on Renal Elimination, and Can Be Detected in Urine Samples

Olof Gidlof et al.

CARDIOLOGY (2011)

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Article Cardiac & Cardiovascular Systems

Increased MicroRNA-1 and MicroRNA-133a Levels in Serum of Patients With Cardiovascular Disease Indicate Myocardial Damage

Yasuhide Kuwabara et al.

CIRCULATION-CARDIOVASCULAR GENETICS (2011)

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miR-499 regulates mitochondrial dynamics by targeting calcineurin and dynamin-related protein-1

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NATURE MEDICINE (2011)

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Characterization of extracellular circulating microRNA

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NUCLEIC ACIDS RESEARCH (2011)

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Review Physiology

MICRORNAS IN DEVELOPMENT AND DISEASE

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PHYSIOLOGICAL REVIEWS (2011)

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Article Cardiac & Cardiovascular Systems

MicroRNAs Add a New Dimension to Cardiovascular Disease

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CIRCULATION (2010)

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Article Cardiac & Cardiovascular Systems

Circulating MicroRNAs in Patients With Coronary Artery Disease

Stephan Fichtlscherer et al.

CIRCULATION RESEARCH (2010)

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Plasma MicroRNA 499 as a Biomarker of Acute Myocardial Infarction

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CLINICAL CHEMISTRY (2010)

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Article Medicine, Research & Experimental

A translational study of circulating cell-free microRNA-1 in acute myocardial infarction

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CLINICAL SCIENCE (2010)

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Article Cardiac & Cardiovascular Systems

Circulating microRNAs are new and sensitive biomarkers of myocardial infarction

Yuri D'Alessandra et al.

EUROPEAN HEART JOURNAL (2010)

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Article Cardiac & Cardiovascular Systems

Circulating microRNA: a novel potential biomarker for early diagnosis of acute myocardial infarction in humans

Guo-Kun Wang et al.

EUROPEAN HEART JOURNAL (2010)

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Article Cardiac & Cardiovascular Systems

MicroRNA-320 Is Involved in the Regulation of Cardiac Ischemia/Reperfusion Injury by Targeting Heat-Shock Protein 20

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CIRCULATION (2009)

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Article Cell Biology

被撤回的出版物: The muscle-specific microRNAs miR-1 and miR-133 produce opposing effects on apoptosis by targeting HSP60, HSP70 and caspase-9 in cardiomyocytes (Retracted article. See vol. 124, pg. 3187, 2011)

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JOURNAL OF CELL SCIENCE (2007)

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Article Cardiac & Cardiovascular Systems

Biomarkers in acute cardiac disease - The present and the future

Allan S. Jaffe et al.

JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY (2006)

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The role of microRNA-1 and microRNA-133 in skeletal muscle proliferation and differentiation

JF Chen et al.

NATURE GENETICS (2006)

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An extensive class of small RNAs in Caenorhabditis elegans

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SCIENCE (2001)

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